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» LymeNet Flash » Questions and Discussion » Medical Questions » Clindamycin Question

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Author Topic: Clindamycin Question
seekhelp
Frequent Contributor (5K+ posts)
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I'm taking this now (330 mg 3x day). I started today and it's knocking me down. Wow, is this possible? I was feeling fairly decent the last 3-4 days and then started this. Within 10-15 minutes after starting, my body feels like all the energy is drained. Not fun. Does it go away? Is it that powerful?

My ID doc started me on this for 10 days for an elevated ASO-strep test.

One more thing...anyone take Clindamycin AND Malarone? My ID doc doesn't think I have Babs so I can't possibly ask him. [Smile]

Posts: 7545 | From The 5th Dimension - The Twilight Zone | Registered: Mar 2008  |  IP: Logged | Report this post to a Moderator
seekhelp
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/\ Bumping. I read historical posts on Clindamycin, but many were Babesia-related.
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KS
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I took clindamycin with plaquenil and definitely can relate to how you are feeling. Can't say for sure whether it was the clindamycin or plaquenil though. I was fine initially and then started feeling the impact within a week.

I believe it is o.k to take with malarone. I did a quick search and didn't see any warnings.

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seekhelp
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Thank you very much. I feel better knowing I'm not losing my mind. Did the drug help you much?
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KS
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Hard for me to say whether the clind/plaq. really helped me or not. By the third week on it I was 10-fold sicker than I have ever been and ended up being hospitalized for almost a week....didn't think I would make it. I believe it was a horrible herxheimer reaction. When I came out of the hospital, I had a PICC line and did IV Rocephin for a month.

After that I did another 2 months of Biaxin/Plaq and didn't experience that degree of a herxheimer reaction again. I certainly have the cycling of symptoms like most on here but this was a very acute reaction for me when originally on these meds. It didn't make me feel better but clearly it was doing something and was probably part of the healing/treatment process.

The one symptom that was unique to this combo of meds for me was the 'gloom and doom'. Didn't feel that prior to treatment or while on other antibiotics. I eventually tried other meds as well and am feeling decent these days. Unfortunately I can't attribute improvement to any one combo of meds. Overall though, clind. is usually well tolerated by most.

Again, my experience may not have been due to the clindamycin alone but also the plaquenil as well. I'd give your body another week to adjust and see how you feel.

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