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» LymeNet Flash » Questions and Discussion » Medical Questions » NADP -> NAD as a result of photon transfer - please don't be afraid to read

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Author Topic: NADP -> NAD as a result of photon transfer - please don't be afraid to read
Marnie
Frequent Contributor (5K+ posts)
Member # 773

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Okay...I get it.

Neat way to block the "cholesterol pathway"!

"each electron extracted from H2O requires

***two photons to be donated to NADP***"

"The Coin of Life: "NAD+ and ATP are the energy currency for the cell.

Money is a medium of exchange. People assign work for us to do, we receive money for doing it, and we convert that money into things we want or need.

The cell takes its energy source, converts it into NAD(H) and ATP, and then uses them to perform needed tasks in the cell.

NAD+ and ATP are not the only carriers of energy, but they are the major ones."

"NAD is a coenzyme facilitating the process where sugar (pyruvate) transforms to lactate. The heart muscle only uses lactic acid as its major source of energy. Two well-known factors reduce NAD in the body and that is alcohol (part of the liver detox process)

and exercise."

"Nicotinamide Adenine Dinucleotide (NAD) is most important for energy. If you have too little NAD, some of your enzymatic reactions do not function and then you cannot produce energy. You cannot produce ATP."

***NAD+ is an oxidizing agent.***

"The coenzyme NAD+ is not itself currently used as a treatment for any disease. However, it is potentially useful in the therapy of neurodegenerative diseases such as Alzheimer's and Parkinson disease."

(My note: add to that list Lyme disease.)

"While the Staphylococcus aureus and Borrelia burgdorferi CoADRs exhibit strong preferences for NADPH and NADH, respectively"... PMID: 18399646

So...the above...Bb needs NADPH...

Follow this...

"Whereas many gram-negative bacteria employ the nonmevalonate pathway (26), humans, other eukaryotes, archaea, gram-positive cocci, and the spirochete Borrelia burgdorferi utilize the enzymes and intermediates of the mevalonate pathway" (That is also called the cholesterol pathway.)

Go here and SEE where NADPH and NADP fit in:

http://ukpmc.ac.uk/articlerender.cgi?tool=EBI&pubmedid=15028676

Neat way to interrupt the cholesterol pathway!

And then give MgCl (Mg ALSO inhibits HMG CoA reductase).

Brilliant!

[ 04-25-2009, 07:10 PM: Message edited by: Marnie ]

Posts: 9424 | From Sunshine State | Registered: Mar 2001  |  IP: Logged | Report this post to a Moderator
   

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