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» LymeNet Flash » Questions and Discussion » Medical Questions » tigecycline and nausea

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Author Topic: tigecycline and nausea
ThatColorGreen
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did anyone else have really bad nausea with this stuff??

i'm on two anti-nausea meds and nothing is helping. bleh.


~green~

--------------------
...trying to be the coffee bean, not the egg.

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kreynolds
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I was on Tygacil and had bad nausea, but thought that it was the most effective IV ABX I have been on.

I don't fare well with anti-nausea meds...

If you don't mind me asking what are the anti-nausea meds?

For myself Reglan put me in the worst anxiety/depressed state I have ever been in and I recently saw a commercial about the drug....

--------------------
Diagnosed CDC + 6/2007

Quest: + IGG Bands 18,23,39,41,58,66 and 93.

Quest: + IGM Bands
23,39

Quest: + Bartonella (B.Henselea & B. Quintana),+ Babesia, and + Mycoplasma and Lyme-Induced Addisons Disease

+ Biofilm blood test 12/2010

Posts: 1185 | From New York | Registered: Apr 2008  |  IP: Logged | Report this post to a Moderator
Tracy9
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KReynolds, were you able to stay on the med? From what I've heard very few people can tolerate it. I was very interested in it myself but my LLD stopped using it because his patients were having so many side effects.

Has anyone successfully used it long enough to get better? How long have you been on it Jen?

--------------------
NO PM; CONTACT: [email protected]

13 years Lyme & Co.; Small Fiber Neuropathy; Myasthenia Gravis, Adrenal Insufficiency. On chemo for 2 1/2 years as experimental treatment for MG.

Posts: 4480 | From Northeastern Connecticut | Registered: Jun 2005  |  IP: Logged | Report this post to a Moderator
kreynolds
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Tracy9,

Yes, I was on IV Tygacil for 4 months.

I was told that it is even better than Rocephin at breaking the BBB.

The only reason I went off of it was because I felt it wasn't hitting my Co's.

I am on IV Doxy now, but if I had to switch again it would be to the Tygacil, no doubt.

Seemed to help with a lot of Neurological symtoms.

Many people I know that have been on it had to stop it because of the stomach problems, but I just juiced myself with probiotics.

In my opinion, I think it's the best IV ABX out there for LYME....

Don't know how well it hits the Co's, it didn't seem to hit them hard...

--------------------
Diagnosed CDC + 6/2007

Quest: + IGG Bands 18,23,39,41,58,66 and 93.

Quest: + IGM Bands
23,39

Quest: + Bartonella (B.Henselea & B. Quintana),+ Babesia, and + Mycoplasma and Lyme-Induced Addisons Disease

+ Biofilm blood test 12/2010

Posts: 1185 | From New York | Registered: Apr 2008  |  IP: Logged | Report this post to a Moderator
Tracy9
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Wow, good to hear. I was told by my last LLD it was the best, he sent me to the new guy to get it, and the new guy gave me Rocephin instead.

Hmmm. That was working really well for me too though until I had no more line. Still working on that one though.

--------------------
NO PM; CONTACT: [email protected]

13 years Lyme & Co.; Small Fiber Neuropathy; Myasthenia Gravis, Adrenal Insufficiency. On chemo for 2 1/2 years as experimental treatment for MG.

Posts: 4480 | From Northeastern Connecticut | Registered: Jun 2005  |  IP: Logged | Report this post to a Moderator
kreynolds
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Tracy9,

Yeah, I am not a big fan of Rocephin although it has helped many out.

I think the new IV ABX to beat it definately the Tygacil...

--------------------
Diagnosed CDC + 6/2007

Quest: + IGG Bands 18,23,39,41,58,66 and 93.

Quest: + IGM Bands
23,39

Quest: + Bartonella (B.Henselea & B. Quintana),+ Babesia, and + Mycoplasma and Lyme-Induced Addisons Disease

+ Biofilm blood test 12/2010

Posts: 1185 | From New York | Registered: Apr 2008  |  IP: Logged | Report this post to a Moderator
ThatColorGreen
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started the tygacil on wednesday and have had nonstop nausea since then.

i have zofran and medical marijuana (pill form) for my nausea, but either does anything; i swear the Med. Mari. is a placebo.

anyway, yea.. i was reading about tygacil on their website before i started taking it; in regards to its effectiveness against forming resistant strains of bacteria, etc etc

then when my llmd was talking about it, he said pretty much what kreynolds said.

only thing though is i can barely put anything into my mouth after my first dose; so there goes the second dose of my mepron! (which by itself is enough to make you barf)

but yea, haven't even been on it for a week and cannot get rid of this nausea. i'm calling the office tomorrow to see if he has any other suggestions as per nausea meds.

Tracy, the rocephin didn't do much for me when i was on it; then again, that was with the doc who originally dx me. only had me doing 1g/day once or twice a week.. i think i did that for five weeks while on doxy... so yea....

anyway, i'll let you know how this one turns me around. as far as my nausea and emotions are concerned, this one is NO Fun.

...I'll keep you updated :I

xoxo
~The Green One~

--------------------
...trying to be the coffee bean, not the egg.

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Tracy9
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Wow, even my 13 year old 75 pound son takes 2 grams a day of Rocephin every day of the week....can't imagine why yours didn't work.....ahem!

Once I ever get a line in I'll give the Rocephin another try, hopefully soon. Blake is doing very, very well with it.

It did cause me profound fatigue though by the second month, but I've heard the Tygacil is even worse. Does it make you exhausted?

--------------------
NO PM; CONTACT: [email protected]

13 years Lyme & Co.; Small Fiber Neuropathy; Myasthenia Gravis, Adrenal Insufficiency. On chemo for 2 1/2 years as experimental treatment for MG.

Posts: 4480 | From Northeastern Connecticut | Registered: Jun 2005  |  IP: Logged | Report this post to a Moderator
kreynolds
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Tygacil WILL make you exhausted and nauseous.....

I think the pro's out weigh the cons in the long run.

ThatColorGreen,

I know it sucks, but hang in there....

Definatley call your doc to see if you can be put on something, in my opinion stay away from the Reglan......

--------------------
Diagnosed CDC + 6/2007

Quest: + IGG Bands 18,23,39,41,58,66 and 93.

Quest: + IGM Bands
23,39

Quest: + Bartonella (B.Henselea & B. Quintana),+ Babesia, and + Mycoplasma and Lyme-Induced Addisons Disease

+ Biofilm blood test 12/2010

Posts: 1185 | From New York | Registered: Apr 2008  |  IP: Logged | Report this post to a Moderator
dmc
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Was on it 4 months...the nausea does go away...I nibbled on crackers & ginger ale.

Every time I went in kitchen took a few of the cheaper acidopholis/probiotics too.

Other than the first month being tough I too feel it is the best IV treatment for the "tough neuro-muscular cases". Since stopping in Oct.08 (blood clots) I have not backslided.

I did begin to be able to eat while infusing. Stick it out... It's worth it.

Posts: 2675 | From ct, usa | Registered: Jan 2004  |  IP: Logged | Report this post to a Moderator
   

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