Topic: That 3rd eye LOCATION (WFL) maybe invaluable!
Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
The Western Fence lizard maybe "unique" in that it has a 3rd eye (pineal gland) in an odd location (in addition to its blue belly which is absorbing the red wavelength).
Some general info first:
When a tick attaches to a lizard, the substance in the lizard's blood enters the tick and kills the Lyme disease bacteria inside the tick. As a result, areas that have lots of western fence lizards have a low prevalence of ticks infected with Lyme disease. Therefore, a large population of lizards reduces the possibility of Lyme disease infection in humans.
The male Western Fence Lizard is typically territorial (Eisen et al., 1997). Nussbaum et al., (1983), and Brown et al., (1995) report on the general behavior of Western Fence Lizards:
They are usually active from after sunrise to dusk and ***sometimes during the night*** depending on the warmth.
In order to be able to see at night, it has to have a lot more rods than cones in its eyes = rhodopsin.
SUPPLEMENTS Reptiles require calcium in their diets and dusting the first dozen insects three days a week with Repcal Calcium will meet that requirement.
It has a gene to export calcium OUT and it has a PKC INHIBITOR (P=protein, K= kinase = transfer phosphate, C= calcium activated).
I think Bb's PKC inhibitor is more specifically, PKCd. Delta.
Back to the Lizard,
"It might be useful here to note the various locations of other animal's pineal glands.
The most popular creature in third eye studies is the Western Fence Lizard-Sceloporus occidentalis.
This little gentleman not only has a fine and functional pineal gland but also a photoreceptive element plainly called a 'third eye'.
The pineal of the Western Fence Lizard is located directly on top of the head.
A small opening (foramen) can be seen in the skull where the 'third eye' actually protrudes. "
"Light-dependent Activation of Rod ***Transducin*** by Pineal Opsin"
These results demonstrate that P-opsin is an efficient catalyst for activation of rod transducin and suggest that the pineal gland may contain a rodlike phototransduction cascade.
� More melatonin can be made and -> increased melatonin functions as an anti-oxidant...and this affords Bb protection against free radical damage?
Then becuase of the toxin, melatonin suppresses macrophage COX-2 and iNOS expression.
-> less nitric oxide made?
Nitric oxide isn't available to destroy Bb?
Link to Ca and NO?
"Ionic calcium is crucial for the synthesis of vasoactive substances in the endothelium as prostacyclin and *nitric oxide*. Recent results suggest that an alteration in the action of NO may be related to a high inactivation by free radical superoxide, secondary to an inflammatory process."
Now, to infect us, Bb, on its way out of the tick, picks up a protein from the tick's saliva called SALP 15.
"The binding of Salp15 protected B. burgdorferi from antibody-mediated killing in vitro and provided spirochaetes with a marked advantage when they were inoculated into naive mice or animals previously infected with B. burgdorferi."
Watch for calcium mentioned:
Salp15 is an Ixodes scapularis salivary protein that inhibits CD4+ T cell activation through the
***repression of TCR ligation-triggered calcium fluxes and IL-2 production.***
We show in this study that Salp15 binds specifically to the CD4 coreceptor on mammalian host T cells.
Salp15 specifically associates through its C-terminal residues with the outermost two extracellular domains of CD4.
Upon binding to CD4,
Salp15 inhibits the subsequent TCR ligation-induced T cell signaling at the earliest steps
including tyrosine phosphorylation of the Src kinase Lck, downstream effector proteins, and lipid raft reorganization.
These results provide a molecular basis to understanding the
immunosuppressive activity of Salp15 and its specificity for CD4+ T cells.
It appears to me that Bb does NOT want calcium to activate nitric oxide.
Which brings me to the "magic five" nutrient supplements that are very helpful in MANY cancers:
ascorbic acid, green tea extract (these would tame down our immune system) and alanine (nitric oxide), lysine and proline.
Tame down the immune system (TNF alpha AND IL 1B) and at the same time, restore the amino acids that Bb depletes?
Bb steals 2 phosphates from 2 serine-proteins and uses them to make glutamic acid which it then metabolizes to GABA. GABA A and GABA C are chloride channels = fast inhibition.) GABA B is not a chloride channel = slow inhibition.
Frontline, to PREVENT lyme in our dogs, blocks chloride channels!
Now the chloride channels are open and in goes NaCl (Bb needs Na for its Na-ATPase and NaCl for motility). Close "second"...in goes Ca... to try to activate PKC, but Bb has no use for Ca and exports it.
NaCl and CaCl are "de-icers". So is MgCl (which is what is really needed), but Na and Ca are more "reactive" than is Mg to make hydrogen.
It would take a LOT of MgCl to displace NaCl and CaCl and it takes ATP to drive Mg back into the cells.
The infected cells are making far too little ATP as they are functioning solely on glycolysis. There is "mitochondrial dysfunction" happening...as Bb is robbing the mitochondria of the nutrients it needs to perform "oxidative phosphorylation" to make a LOT more ATP.
Instead of NaCl and CaCl (or MgCl) as "de-icers"...we can "heat" the cells using sound or light.
Rife/far infrared.
Those cells that are the "coldest" will be the first to be impacted.
I'm pretty sure what the Western Fence lizard produces a lot of to destroy Bb is
transducin
(when light hits the "3rd eye" and activates it - which closes the TRPM8 channel and impacts the
export of calcium.
That lizard NEEDS Ca, Bb does NOT. And Ca helps us to make NO = nitric oxide.
Bartonella and bordetella pertussis both look to bind to Ca as does tetracyclines.
What it looks like we really need is to prevent Ca from LEAVING the infected cells...block the export to counter Bb's PKC inhibitor.
Close the TRPM8 channel which in specific cells like LNCAP (lymph node cancer prostatic) that channel is functioning as a calcium RELEASE channel.
....to the best of my ability.
[ 06-03-2009, 07:10 PM: Message edited by: Marnie ]
Posts: 9424 | From Sunshine State | Registered: Mar 2001
| IP: Logged |
Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Up all you lizard lovers!!!
The WFL holds the key to what destroys Bb.
[ 06-03-2009, 07:11 PM: Message edited by: Marnie ]
Posts: 9424 | From Sunshine State | Registered: Mar 2001
| IP: Logged |
bejoy
Frequent Contributor (1K+ posts)
Member # 11129
posted
Marnie, you are amazing!
I'll be off to Western Fence Lizard land this summer, and hope to commune with the critters. Maybe they'll whisper a little something in my ear.
Probably they'll tell me to soak up the sun, right between the eyes.
-------------------- bejoy!
"Do not go where the path may lead; go instead where there is no path and leave a trail." -Ralph Waldo Emerson Posts: 1918 | From Alive and Well! | Registered: Feb 2007
| IP: Logged |
Wow...some far out stuff on You Tube re: the pineal if you click on a link in the above link.
Now getting into the "hard to believe, but" area.
Theta waves.
Circling back to a CD called "Deep Meditation" (MUST be listened to wearing headphones. About 1 hour long.)
It IS incredibly relaxing..I have it. I "multi-tasked"...listen to it while on a recumbant exercise bike...slow pedalling.
It has a "background" tone throughout the CD if you listen closely...a carrier wave?
Can specific "soundwaves" actually help us to heal?
Of course, light is more powerful, but...
I'm keeping a very open mind.
There are a lot of older cultures who had some very interesting ideas.
Meditation.
Those of you who are near my age ;-) maybe remember:
"Transcendental Meditation". When Yoga first became popular here in the U.S.
About the same time as...the "Age of Aquarius"...
Hippy era.
Remember the Gregorian Chants CDs by Benedictine Monks of St. Michael's?
They were popular many moons ago.
We have everything on this planet we "need"...finding it is key.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
| IP: Logged |
Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Bottom line...in that lizard's blood is a helper protein called *transducin* which looks to "close" a channel called TRPM8 and that, my friends, looks to be absolutely necessary to destroy Bb.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/