Bugg
Frequent Contributor (1K+ posts)
Member # 8095
posted
As I've posted in the past, I've wondered about the most effective way to raise glutathione levels.
Some abstracts will say that the oral administration of methyl ester glutathione can be effectively absorbed. Other types are mainly wasted in the intestinal tract. Some say liposomal glutathione can be absorbed...others say not...
I think, however, it's pretty well-established in the medical journals that orally taking precursers such as NAC is an effective way to raise intracellular glutathione levels.
I have two concerns, and I'll keep repeating these concerns (until hopefully I can find the answer or all of you smart ones on this board figure this out):
1) Are people using the most effective means to raise their INTRACELLUAR GLUTATHIONE LEVELS...ie. those that impact mitochondrial ATP..if they only use IVs occasionally,IMs occasionally, the cream, the nebulized version....or are they mainly increasing their EXTRACELLULAR LEVELS( i.e. blood levels) with minimal intracellular impact....
(this obviously effectuates detox but does it replace depleted glutathione???)
To have the most impact at an intracellular level, do we either need to be taking the precurers such as NAC or methyl esther glutathione...
Can someone ask their doc?
2)Are you mitigating the effects of glutathione if you are trying to replenish your glutathione levels while taking antibiotics?
posted
At my appoint last week, my doc gave me a glutathione push to see if I could see a difference, and whether it would be worth spending money on it.
I di not feel I saw any difference, but my all day trip kills me anyway, so who knows?
Posts: 847 | From upstateNY | Registered: Dec 2007
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posted
My doctor just prescribed it in a cream form. I am having it sent from a compouding pharamacy. I don't detox well and my herxes are frome hell.
He is hoping this will help me. I really am too. Kathy
-------------------- Severe neurological problems. Probably sick for years. Became chronically sick in Aug 2007. Undiagnosed for another 15 months. Started treatment for lyme and bart Sept. 2008. Improving, but very slowly. Posts: 515 | From washington dc | Registered: Aug 2008
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luvs2ride
Frequent Contributor (1K+ posts)
Member # 8090
posted
glutathione has been my miracle medicine. It saved my life.
Initially I received weekly IVs then bi-weekly then monthly. Today I use suppositories. I can't say if they are as effective because today I live a normal life and don't have pain.
A gene test reveals I am very defective in my ability to produce my own glutathione so I will take supplement of it for life.
-------------------- When the Power of Love overcomes the Love of Power, there will be Peace. Posts: 3038 | From america | Registered: Oct 2005
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karenl
Frequent Contributor (1K+ posts)
Member # 17753
posted
Acete glutathione there is a post, please read.
Posts: 1834 | From US | Registered: Oct 2008
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Bugg
Frequent Contributor (1K+ posts)
Member # 8095
posted
Karenl-I'm assuming you are talking about acetylglutathione...if that's not right, please let me know...I sent you a PM.....thanks!
Yes, I'm thinking about trying the Acetylglutathione version...been asking others on this board about their experiences, thus far..
I found, what appears, to be the answer to part of my questions above in an Orthomolecular text which states the following:
1)GSH can be absorbed intact by epithelial cells such as those in the lungs, vessell endothelial cells, retinal pigmented epithelial cells, and cells of the kidney's proximal tube. It can also be directly absorbed into the lungs via an aerosol 2) Brain endothelial cells, nerve cells, red blood cells, and lymphocytes are INCAPABLE of absorbing GSH as the intact tripeptide; it must be synthesized from cysteine.(hopefully the acetylglutathione will suffice in this instance)It appears that exogeneous sources such as IVS or IMs or creams of glutathione would be less effective in this instance????.....
***The book goes onto say that intracellular GSH of lymphocytes dtermine the magnitude of immunological activity
***Chronic viral infections may trigger GSH depletion (I've been reading some studies where they are administering acetyl-glutathione for viruses such as HSV-1 with success)...
Posts: 1155 | From Southeast | Registered: Oct 2005
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TerryK
Frequent Contributor (5K+ posts)
Member # 8552
posted
You may want to look into the glutathione depletion theory regarding methylation cycle issues. This may give you an added direction.
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