Dekrator48
Frequent Contributor (5K+ posts)
Member # 18239
posted
I had this done but I don't think it was necessary because I had other lyme specific bands present as either + or IND.
-------------------- The fibromyalgia I've had for 32 years was an undiagnosed Lyme symptom.
"For I know the plans I have for you", declares the Lord, "plans to prosper you and not to harm you, plans to give you hope and a future". -Jeremiah 29:11 Posts: 6076 | From Pennsylvania, USA | Registered: Nov 2008
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
I did. I think it is useless unless you got the jab.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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posted
I've never seen anyone who tests NEG to it! I think I've read that IgeneX rate is 96% thus leaving a 4% chance of a false positive caused by a virus...on band 31.
seekhelp
Frequent Contributor (5K+ posts)
Member # 15067
posted
Kareamber, I think you're misinterpreting that statistic for this question.
Posts: 7545 | From The 5th Dimension - The Twilight Zone | Registered: Mar 2008
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
I was neg. yet at the same time +++31kDa . WB Igenex pos. I did
not get the jab. It does not mean my kDa band is
caused by something other than Bb. It simply means
it did not show in the sample. But I do think I have some viral load.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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quote: IGeneX also now offers a new 30-31kDa Confirmation IgG and IgM test. If results from the initial Western Blot are positive for bands 30 or 31, it is possible that these could be due to cross-reactivity with several different types of viruses. In this confirmatory test, highly specific recombinant antigens are used to validate that the positive result is not due to cross-reaction with viruses. If ONLY band 31 is positive and no other specific bands are positive, it is recommended to have tests #488 and #489 31 kDa epitope Igm/Igg to make sure borrelia hasn't crossed reacted with several possible viruses....but AGAIN ONLY IF BAND 31 ALONE is positive.
IGeneX website
quote: A positive IgG result with clinical history may be indicative of Lyme disease. Patients with other spirochetal disease and/or who test positive for rheumatoid factor or Epstein Barr virus may have cross-reacting antibodies. A positive response in this, as in any antibody assay, indicates sensitization, not necessarily active disease. 12
quote: because the literature suggests that rheumatoid conditions may lead to false positive IgM antibody responses, an ANA/DNA/rheumatoid factor screen may be ordered to rule out false positive reactions. Patients testing positive with serologic tests for syphilis may also test positive for the Lyme antibody tests.13-15
And, perhaps, the source of "96%" Jyotsna S. Shah article
quote: Using IGeneX criteria, the in-house assay sensitivity increased from 46% to 68% for IgG WB and from 76% to 81% for IgM WB. The specificity decreased from 99% to 96%. However, the overall in-house WB assay sensitivity increased from 76% to 89%.
You will note that the 96% number is specific to specificity!Posts: 426 | From Berkeley, CA | Registered: Feb 2009
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
Just my opinion but I think they use it for
patients who are possible vaccine patients to
prevent treatment for something that isn't really
there? Am I correct? But in any event I am not sure
that would be the case and it would be dependent on
the LLMD to decide? Meaning I do think it is
possible transmission was missed. Heck they
missed it in me for over 2 years.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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posted
Well I haven't had the vaccine, I've been screened for RA several times which is neg, and I'm NEG for Syphilis.
I contacted my LLMD to see again if he thought it was necessary, but I haven't heard back yet. I don't want to scoop out the money if it isn't necessary.
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