posted
I recently had another western blot test (quest - so they only reported the CDC bands) that showed IGG band 58 was "reactive". Everything else was negative.
Is it possible that this is indicative of something other than Bb?
Thanks!
-------------------- "Sometimes trouble just follows a man" - Clint Eastwood as Josey Wales Posts: 40 | From Pittsburgh, Pennsylvania | Registered: Aug 2007
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posted
Also should mention that IgM was all negative too
-------------------- "Sometimes trouble just follows a man" - Clint Eastwood as Josey Wales Posts: 40 | From Pittsburgh, Pennsylvania | Registered: Aug 2007
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posted
I just read Dr. C's revised bands that he says are significant (antibodies) in 2005. He included band 58 at this time.
However, band 58 is listed as one that can be cross-sensitive with other bacterial protein. Many docs want this removed from the CDC IgG criteria list.
Any help or thoughts would be appreciated here. Too bad your tongue doesn't turn black or something easy to identify like that.
-------------------- "Sometimes trouble just follows a man" - Clint Eastwood as Josey Wales Posts: 40 | From Pittsburgh, Pennsylvania | Registered: Aug 2007
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Hoosiers51
Frequent Contributor (1K+ posts)
Member # 15759
posted
Ha, good point with the last statement. Too bad indeed.
Yes, unfortunately from what I understand, 58 cannot point to Lyme only.
However, sometimes bands will not show up in testing for whatever reason (bad tests, Lyme not prevoked enough before testing, immune system not recognizing it), so because of that, physicians will sometimes treat clinically, on suspicion of Lyme.
A better lab like Igenex or Stony Brook might catch more bands for you. Or, sometimes more bands will come back positive after taking antibiotics, or later in treatment.
However, what you have in the bloodwork you've done so far is not enough to come to any definitive conclusions, on its own. Posts: 4590 | From Midwest | Registered: Jun 2008
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
I would take Quest with a grain of salt.
I would do a challenge and retest with Igenex.
My first quest was one band migrating in IgG region unable to identify in 07. Sick for over 2
years and could have found it a lot sooner if I had known.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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-------------------- "Sometimes trouble just follows a man" - Clint Eastwood as Josey Wales Posts: 40 | From Pittsburgh, Pennsylvania | Registered: Aug 2007
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
You take a short course of antibiotics wait 10 days
and draw and ship to Igenex. It has been found that
way in patients who are immuno compromised by
killing some of it where by the immune system
produces antibodies to the dead/dying Borrelia
where before it did not see them. No antibodies
means no detection. I think this explains it.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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