posted
could someone tell me the difference between these two drugs when treating severe bart. My daughter was just put on rifampin and I have noticed that she is very moody, like pms all the time. Is this a bad thing, would factive be a better choice?
Posts: 256 | From Boston, mass | Registered: Jan 2008
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posted
Factive is fluorquinolone .Google "fluorquinolone dangers". Rifampine seems to have much milder side effects profile .I dunno about effectiveness though
Posts: 856 | From MA | Registered: Jul 2009
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METALLlC BLUE
Frequent Contributor (1K+ posts)
Member # 6628
posted
Factive is much safer than the other drugs in that family. It's one of the new generation antibiotics.
-------------------- I am not a physician, so do your own research to confirm any ideas given and then speak with a health care provider you trust.
posted
I started Factive tonight. Blue, where do you get your safety data? Thanks!! Kris
Posts: 520 | From Maryland | Registered: Jan 2007
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sammy
Frequent Contributor (5K+ posts)
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posted
How old is your daughter? If she is under 18 she should not take fluoroquinolones (Factive, Levaquin, Cipro, Avelox). This class of antibiotics is known to cause joint and bone problems in young animals so they do not recommend using it in children.
Did your daughter just start treatment with the Rifampin? Remember, when starting new antibiotics we often feel worse before we begin to feel better.
You should give your daughter time to adjust to the Rifampin, if after 4-6wks she is still feeling/acting worse then talk with her doctor about changing meds.
Posts: 5237 | From here | Registered: Nov 2007
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Hoosiers51
Frequent Contributor (1K+ posts)
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posted
In my opinion, you're best to give the Rifampin 6 weeks before calling it quits. I've read in "The Lyme Disease Solution" that you will normally know Rifampin is working, I want to say 3 weeks in....but I'd give it up to 6 to be sure.
I can't remember what he says is normally when the improvements really start to show on Rifampin, but like I said, I think it was 3 weeks. If you'd really like to know, let me know and I'll go look it up.
I did Rifampin for 6 weeks, then ditched it, because it was making me so tired, probably as a side effect. My bartonella responds very quickly to meds, so I know usually pretty soon whether or not it's gonna work.
Bactrim DS can work really well against Bart...that is another one to give a try. Worked much better for me than Rifampin, but everyone's different.
I have tried Cipro (a fluroquinolone), and that didn't help that much, but I'm still interested in eventually trying Factive or Levaquin. So far Bactrim DS is my favorite for Bart.
Posts: 4590 | From Midwest | Registered: Jun 2008
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Hoosiers51
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Member # 15759
posted
ps--to answer your question, the moodiness is not necessarily a bad thing, unless after awhile she fails to improve on the drug.
Just try to be as understanding as you can, because those emotional reactions are rough to go through.
Cipro made me really moody too. It might have helped me a little, but in the end, it felt like it stirred up more, than it actually got rid of symptoms.
Posts: 4590 | From Midwest | Registered: Jun 2008
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posted
I've been on Rifampin for two weeks now and the first 5 days were bad. I was very emotional and moody, also felt somewhat hopeless and had a strong herx as well, but am also on Minocycline and Zithromax as well, so some of that could be related to those abx. Just wanted you to know it did pass and I am actually seeing some improvement in symptoms.
Dr. Singleton says in his book to expect a herx-like reaction the first week and then to see improvement by week two or three.
I'd say try and hang in there and see how it goes after a few days.
Haven't tried Factive so I don't have any input there!
Aimee
Posts: 239 | From Virginia | Registered: Jun 2009
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