posted
Do any of you know if grapefruit seed extract, like grapefruit juice, can be problematic for the liver?
I know that grapefruit juice is processed via the P450 pathway and that it can interact with a lot of meds. But I can't find any definitive answers regarding GSE...
I am wondering because, after 3 weeks on GSE and working up to 12 drops twice daily, I am having some slight pains around my mid right flank and back, the same place that periodically aches when I take Diflucan for a few weeks. Other than that, I haven't noticed much in the way of a herx or improvement.
Thanks for any insight!
-------------------- Increasingly ill over past 10 yrs; treating since October '08. Posts: 180 | From Philadelphia, PA | Registered: Oct 2008
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posted
Thanks ninjaphire - dieoff would be a positive reason for the discomfort!
Today, in fact, I started feeling more of what seems like a herx: stronger headache, fatigue, feeling out of it. I take lots of liver support - milk thistle, schizandra, NAC, beta carotene, among others. Maybe I need to reduce my dose a bit...
-------------------- Increasingly ill over past 10 yrs; treating since October '08. Posts: 180 | From Philadelphia, PA | Registered: Oct 2008
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posted
I am no dr or expert but my nutritionist, that works with my lyme dr, told me that GSE messes with the detox pathways of the liver and that it can be problematic when taking liver-stressing abx as well.
I stopped taking it daily but still take it once a week (10 drops/twice a day) on the weekends. Helps me with yeast issues. I alternate that OLE and Oil of Oregano.
Just thought I'd share what she told me...
Posts: 114 | From Atlanta, GA | Registered: May 2009
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quote:Originally posted by landerss: Today, in fact, I started feeling more of what seems like a herx: stronger headache, fatigue, feeling out of it. I take lots of liver support - milk thistle, schizandra, NAC, beta carotene, among others. Maybe I need to reduce my dose a bit...
Or you could pulse your dose. I take GSE on weekends, and amoxi on weekdays. (With other abx)
Posts: 330 | From Colorado, USA | Registered: Nov 2008
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posted
bncrump, that's really affirming to hear; I was wondering why I was feeling so toxic on GSE. I have had problems with Diflucan and Rifampin in the past, and my experience on GSE was feeling similarly.
The pulsing/alternating ideas are great - that's what I'm going to do. I already take Oregano Oil and OLE daily - and taking GSE just on weekends sounds like a good plan.
You guys are awesome!
Lynne
-------------------- Increasingly ill over past 10 yrs; treating since October '08. Posts: 180 | From Philadelphia, PA | Registered: Oct 2008
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