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» LymeNet Flash » Questions and Discussion » Medical Questions » Can someone please post the Igenex WB interpratation? I can't find it when I search

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Author Topic: Can someone please post the Igenex WB interpratation? I can't find it when I search
BackinStOlaf
Frequent Contributor (1K+ posts)
Member # 23725

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thank you in advance

--------------------
First Symptom 9/09
Multiple docs, negative Labcorp test
LLMD: 1/10
Positive Igenex/CDC test
Treatment 2/10
2/10-8/10 Amox, ceftin, zith, flagyl
Currently: Bicillin, Minocycline, still dealing with severe breathing issues

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Posts: 1121 | From New York, New York | Registered: Dec 2009  |  IP: Logged | Report this post to a Moderator
Keebler
Honored Contributor (25K+ posts)
Member # 12673

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www.igenex.com

IGENEX

=================

Dr C's Western Blot explanation is discussed here:

http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=042077

"With most infections, your immune system first forms IgM antibodies, then in about 2 to 4 weeks, you see IgG antibodies. In some infections, IgG antibodies may be detectable for years.

Because Borrelia burgdorferi is a chronic persistent infection that may last for decades, you would think patients with chronic symptoms would have positive IgG Western blots.

But actually, more IgM blots are positive in chronic borreliosis than IgG. Every time Borrelia burgdorferi reproduces itself, it may stimulate the immune system to form new IgM antibodies.

Some patients have both IgG and IgM blots positive. But if either the IgG or IgM blot is positive, overall it is a positive result.

Response to antibiotics is the same if either is positive, or both. Some antibodies against the borrelia are given more significance if they are IgG versus IgM, or vice versa.

Since this is a chronic persistent infection, this does not make a lot of sense to me. A newly formed Borrelia burgdorferi should have the same antigen parts as the previous bacteria that produced it.

But anyway, from my clinical experience, these borrelia associated bands usually predict a clinical change in symptoms with antibiotics, regardless of whether they are IgG or IgM."

- (for direct source citation, contact the poster at that thread.)

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Posts: 48021 | From Tree House | Registered: Jul 2007  |  IP: Logged | Report this post to a Moderator
BackinStOlaf
Frequent Contributor (1K+ posts)
Member # 23725

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thank you keebler

--------------------
First Symptom 9/09
Multiple docs, negative Labcorp test
LLMD: 1/10
Positive Igenex/CDC test
Treatment 2/10
2/10-8/10 Amox, ceftin, zith, flagyl
Currently: Bicillin, Minocycline, still dealing with severe breathing issues

 -

Posts: 1121 | From New York, New York | Registered: Dec 2009  |  IP: Logged | Report this post to a Moderator
JunkYardWily
LymeNet Contributor
Member # 24271

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yeah thanks a lot i just spent the last two hours reading about bands [Smile]

--------------------
sick since 9-09
igg, 18,23,41 reactive
igm, 41 reactive

Posts: 436 | From Kansas City | Registered: Jan 2010  |  IP: Logged | Report this post to a Moderator
   

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