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» LymeNet Flash » Questions and Discussion » Medical Questions » Butter is better - some saturated fats are good

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Author Topic: Butter is better - some saturated fats are good
Marnie
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Saturated fatty acids are those

loaded with hydrogen.

Virgin coconut oil contains SATURATED MEDIUM CHAIN fatty acids. The acids in VCO are loaded with hydrogen.

We've been told saturated fats are bad for us.

Well...not ALL of them:

"If saturated fatty acids were of no value or were harmful to humans, evolution would probably not have established within the mammary gland the means to produce saturated fatty acids--*butyric*, caproic, ***caprylic***, capric, lauric, myristic, palmitic, and stearic acids--that provide a source of nourishment to ensure the growth, development, and survival of mammalian offspring.

Goat milk contains the highest percentage of caprylic acid, at 2.7% of milk fat and
Both caprylic acid and capric acid have antiviral activity, and when formed from capric acid in the animal body, monocaprin has antiviral activity against HIV (76, 77).

Caprylic acid has also been reported to have antitumor activity in mice (78). Negative effects of these fatty acids on CAD and cholesterol have not been a dietary issue.

Because saturated fats enhance HDL concentrations, saturated fats are potentially important in protecting against bacterial LPS toxicity.

http://www.ajcn.org/cgi/content/full/80/3/550 American Journal of Clinical Nutrition, Vol. 80, No. 3, 550-559, September 2004

Who here remembers talking about raising goats? Their "smell" is because of caprylic acid. Capricorn...goat. Goat cheese...whew!

"Caprylic acid, octanoic acid, CH3(CH2)6COOH, (in sting of whip scorpions!)"

Caprylic acid appears to be the active component(a particular saturated medium chain fatty acid) in the AD "medicinal food" called Axona.

How it works is amazing (!):

http://www.neurologyreviews.com/ADs/Axona_newsletter.pdf - pay attention to ATP

And here:

http://www.drugs.com/drp/axona.html

Pay attention to HMG CoA!

***If HMG-CoA is reduced
to mevalonate, cholesterol is the only product that can result.***

(Statins inhibit HMG CoA reductase as does Mg. That is to say, HMG CoA is NOT reduced to mevalonate.)

That is the route Bb takes i.e., the "mevalonate/cholesterol pathway" to build his cell walls.

HMG CoA reduced to mevalonate -> cholesterol OR HMG CoA to BHB (ketogenesis) Chart here:

http://en.wikipedia.org/wiki/HMG-CoA

Read more:

http://www.cliffsnotes.com/study_guide/HMG-CoA-Reductase.topicArticleId-24594,articleId-24507.html#ixzz0ggPw8U2P


Keep in mind when reading the above that ATP (increased) turns off PFK1 (phosphofructokinase 1 - rate limiting enzyme for glycolysis).

Guess "who" needs PFK1...Bb.

More...

Short-chain fatty acids, such as propionic, n-butyric, n-valeric, isovaleric, n-caproic, and ***n-caprylic acids***,

***induce alkaline phosphatase activity***

in cultured mammalian cells. Long-chain fatty acids have no similar effects.

http://www3.interscience.wiley.com/journal/109900573/abstract

Alkaline phosphatase removes phosphates from nucleotides, ***proteins***, and alkaloids. The process of removing the phosphate group is called dephosphorylation. (By definition)

Low levels of alkaline phosphatase is seen here:

Hypophosphatasia, an autosomal recessive disease

Postmenopausal women receiving ***estrogen*** therapy because of osteoporosis

***Men with recent heart surgery, malnutrition, magnesium deficiency, hypothyroidism *** or severe anemia

Children with achondroplasia and cretinism

Children after a severe enteritis

Pernicious anemia

Aplastic anemia

Chronic myelogenous leukemia

(Wikipedia)

Okay...if caprylic acid can increase alkaline phosphatase which removes phosphates from proteins, the question is...can it remove phosphates from the SALP 15 protein and render it harmless?

SALP 15 is a protein that Bb cloaks itself in to avoid immune detection. Apparently Bb's OspC protein binds to that protein. It picks up this protein in the saliva of the tick. This protein
-> immunosuppression = low CD4 T cell activation.

We don't know if Bb continues to utilize that protein.

Back to milk...

There is a huge difference in the % of nutrients in mom's milk compared to cow's milk and goat milk. Chart here:

http://goatconnection.com/articles/publish/article_152.shtml

In fact, goat milk has been proposed to give to *children* allergic to cow's milk.

There is even goat milk soap which supposedly:

"Milk has been used for centuries as a cleanser and skin conditioner.

Now scientists believe that goat milk soap has a pH level that is closest to the skins own pH level.

(Our skin is slightly acidic...first barrier for protection.)

The milk contains Caprylic Acid, which assists in reducing the alkalinity of the soap bar.

Cosmetic chemists are calling goat's milk "Nature's Liposome". Goat milk soap is easily absorbed into the skin, bringing with it

***moisture***

and restorative proteins, minerals and Vitamins."

http://www.rainbowridgefarm.net/talk_story.html

By definition:

A liposome is a tiny bubble (vesicle), made out of the same material as a cell membrane. Liposomes can be filled with drugs, and used to deliver drugs for cancer and other diseases.

More info. on goat's milk here:

http://askdrsears.com/html/3/t032400.asp

Taking goat's milk during lyme herxes:

http://www.lyme-disease-research-database.com/coping_with_a_herx.html

While there is conflicting information on the internet re: the presence of Bb (spirochete) OR the presence of Bb's DNA

in breast milk

and what THAT might mean -

what happens if foreign DNA is "given" to a infant who does not have a developed immune system?

Since breast milk contains SOME caprylic acid, it would appear that caprylic acid may not destroy Bb DIRECTLY, but perhaps in some other indirect way (caprylic acid -> BHB -> more ATP
-> less PFK1).

And re: DNA...I couldn't access the entire NEW article that says we DO have a way to ultimately rid foreign DNA from our bodies...

Feb. 10, 2010...

"Cellular defence: Human cells clear foreign DNA "

That may blow away the theory of others who believe we incorporate foreign DNA into OUR own DNA.

I wish I had access to the entire article to see if NEWBORNS have the ability or...not to clear foreign DNA IF Bb's DNA is accidentally transmitted to them in breast milk.

(Note if taking VCO: lauric acid impacts NFkB and IL-8 differently than caprylic acid!)

Note too caprylic acid impacts Na in certain cells:

"Caprylic acid, a medium chain saturated fatty acid, inhibits the sodium inward current in neuroglioma (NG108-15) cells"

Finally...does caprylic acid impact the "export channel protein" called TolC that gram neg. pathogens use to get rid of/export antibiotics, etc.?

In other words, could caprylic acid "potentiate" abx. use OR

What is the impact of HBO on TolC?

(Because high hydrostatic pressure looks to make a difference!!!)

Interesting:

Thus, the deeper one descends under water the greater the pressure. This pressure is called hydrostatic pressure.

Backtracking:

We show that the BesC protein is necessary for B. burgdorferi to establish infection in mice and is involved in

antibiotic resistance.

Furthermore, we determined the biophysical properties of the channel formed by BesC and generated a model of the putative

efflux apparatus.

http://www.plospathogens.org/article/info:doi%2F10.1371%2Fjournal.ppat.1000009

BesC = TolC = a porin.

The crystal structure of TolC, one of the most mysterious *proteins* in the outer membrane of Gram-negative bacteria, suggests a mechanism for its role in

secretion of proteins and efflux of toxic chemicals.

http://www.nature.com/nsmb/journal/v7/n7/full/nsb0700_527.html

Two concentric membranes, the cytoplasmic (or plasma) membrane and an outer membrane fenestrated with protein-based pores, surround Gram-negative bacteria, with an aqueous compartment termed the periplasmic space between the two membranes.

Due to the nature of these membranes, the trafficking of proteins and nutrients in and out of Gram-negative bacteria is much more complex than if only a single membrane were present."

http://www.nature.com/nsmb/journal/v7/n7/full/nsb0700_527.html


Looks like Bb has protein (forming channels) on the outer membrane, water in the middle and then a plasma membrane help to protect this gram negative pathogen. Bb looks to use the multiple layers (with water in the middle) to import and export what "he" needs or doesn't need.

HBO + abx? Pycnogenol/EPA (OmegaBrite) nec. in addition?

As always...all treatments look to impact the friendly bacteria too, so probiotics...lots...always. Vary them.

To the best of my ability.

We WILL find a way.

Posts: 9424 | From Sunshine State | Registered: Mar 2001  |  IP: Logged | Report this post to a Moderator
   

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