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» LymeNet Flash » Questions and Discussion » Medical Questions » Cipro & Plaquenil Question

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Author Topic: Cipro & Plaquenil Question
17hens
Frequent Contributor (1K+ posts)
Member # 23747

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Can anyone help me with this?

I have Lyme and Bartonella at the very least.

I just found an LLMD. First visit was great, second visit was not so good.

At first visit he put me on Andrographis (awesome herb, highly recommend it, cleared my head in a week.) and 2000mg. daily of Amoxy. He had me ramp up so I've been on the full Amoxy for 3 weeks now.

At second visit he told me that this monday i am to start Plaquenil and Cipro for Bart & lyme.

So I'm reading the pharmacy papers and they say that Plaquenil is a malaria drug.

Then I'm reading the booklet, "Lyme Disease and Assoc. Diseases, The Basics" put out the Lyme Disease Assoc. of Southeastern PA. In it, it says Babs (not Bart) is closely related to malaria.

So is he treating me for Bart or Babs? Who's right here? I hate to question my LLMD, but the second appointment really shook me and now I'm not so sure about him. Not a good place to be unfortunately. I wish I trusted him completely by now.

--------------------
"My flesh and my heart may fail, but God is the strength of my heart and my portion forever." Psalms 73:26

bit 4/09, diagnosed 1/10

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Haley
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It could have an effect on Babs but it also changes the Ph in the cell. This allows the medicines to be absorbed better and work better.

I have taken Plaquinel with Zith and I do think it helped the effects. I had some GI issues so I decided to stop it after a while.

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17hens
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Buump!

I guess my question is, "is it bart or babs that's treated with malarial drug?"

Any responses would be appreciated!

--------------------
"My flesh and my heart may fail, but God is the strength of my heart and my portion forever." Psalms 73:26

bit 4/09, diagnosed 1/10

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Beachinit
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Plaquenil is antimalarial but is not anti-babesial. It is used to enhance lyme Bb treatment(usually by giving it along with a macrolide like clarithromycin or azithromycin).
I suspect due to its lysosomal alkalinization
effect it would enhance treatment of bartonella
as well. Quinolones eg levaquin (cipro maybe) is classic for bartonella. While this combo would not likely be lethal for babesia it
probably would put babesia into dormancy for
awhile eg static but not cidal for babesia.
What puzzles me is why give plaquenil with
cipro? Why not clarithro or zithro + plaquenil?

Re: Cipro and Bart:, , ,

Differential phenotypic characteristics of the case isolate compared to those of representative strains of other Bartonella species orsubspeciesa
J Clin Microbiol. 1999 August; 37(8): 2598-2601. PMCID: PMC85292

Copyright � 1999, American Society for Microbiology
Isolation of a New Subspecies, Bartonella vinsonii subsp. arupensis, from a Cattle Rancher: Identity with Isolates Found in Conjunction with Borrelia burgdorferi and Babesia microti among Naturally Infected Mice
The isolate(bartonella) displayed in vitro susceptibility (MIC < 0.5 μg/ml) to ampicillin, penicillin, cefotaxime, ciprofloxacin, chloramphenicol, erythromycin, clarithromycin, and tetracycline. The MIC of gentamicin was 3.0 μg/ml.

Sounds like your MD wanted to attack Bb quick and
short then go right after Bart. Are you having
Bart symptoms?

Barts away,

Beachinit.

--------------------
Ideas not advice.

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17hens
Frequent Contributor (1K+ posts)
Member # 23747

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Yes, almost all of my symptoms are Bart.

--------------------
"My flesh and my heart may fail, but God is the strength of my heart and my portion forever." Psalms 73:26

bit 4/09, diagnosed 1/10

Posts: 3043 | From PA | Registered: Dec 2009  |  IP: Logged | Report this post to a Moderator
   

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