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» LymeNet Flash » Questions and Discussion » Medical Questions » zyprexa---- Who has used this for emerg sleep needs.

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Author Topic: zyprexa---- Who has used this for emerg sleep needs.
Camber
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hi wondering who has used this for sleep?

Anyone who has usual sensitivities with drugs have extra problems with this.


I have traveled and like a lot of lyme patients i have mental health issues when i don't sleep and my body and mind cant regulate.
I am playing with the idea of taking this to catch up on sleep and get a pattern.. As sleep is most important for me to handle my condition. Just not sure how long this will stay in my system and if its really toxic or too toxic for me and my liver.

Posts: 92 | From ri | Registered: Aug 2009  |  IP: Logged | Report this post to a Moderator
rks
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I have sleep problems as well. Have you tried Sleep Tonight and melatonin? The combination may help.
I have not tried what you mentioned, but would do a little research before trying anything.
Good Luck!

Posts: 217 | From Earth | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
Keebler
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As many patients with lyme have trouble with the liver's Cytochrome P450 liver detox pathway, it seems that this would be an unsafe drug for anyone who has such liver considerations.

Use of drugs on the C- P450 list increase liver stress and toxicity, partially a result of (but not necessarily limited to) increased porphyrins which are toxic in excess (see links below).

Reactions can range from mild "hang-over" effect to more serious. For me, nothing could even constitute an emergency that would warrant the taking of a drug that would cause me more toxicity. Even if no sleep is possible, aggressive rest would still be better than this.

If it has increased risk of death from stroke in elderly patients, it probably is also more risky for anyone with compromised health. If it's not safe for Grandma, I don't want it, either.

Some might think a lower dose would be fine but if it triggers a reaction in the liver, side-effects can still be harsh. It's only partly about dose as once a chemical reaction gets going, that can be hard to stop. This is seen in those with multiple chemical sensitivities. Even a whiff or a slight exposure can trigger very serious reactions that can take days to resolve.

The long list of side-effects of zyprexa is a concern for anyone, of any age. This can raise blood glucose, so those with diabetes or blood sugar problems should take note.

===================================

http://en.wikipedia.org/wiki/Zyprexa

Olanzapine (trade names Zyprexa, Zyprexa Zydis, Zalasta, Zolafren, Olzapin, Rexapin or in combination with fluoxetine Symbyax) is an atypical antipsychotic, approved by the FDA for the treatment of schizophrenia and bipolar disorder.[2] . . .

. . . Citing an increased risk of stroke, in 2004 the Committee on the Safety of Medicines (CSM) in the UK issued a warning that olanzapine and risperidone, both atypical antipsychotic medications, should not be given to elderly patients with dementia. . . .

. . . In the U.S., olanzapine comes with a black box warning for increased risk of death in elderly patients. . . .

. . . Olanzapine is metabolized by the cytochrome P450 system isoenzymes 1A2 and 2D6 (minor pathway). . . .

. . . Side effects, adverse reactions [listed] . . .

. . . On January 15, 2009 Eli Lilly plead guilty to a misdemeanor charge of illegally marketing Zyprexa for off-label use, and agreed to pay $1.4 billion.[42] . . . .


- Full article at link above, with citations listed for further study.

===========================

This relates to drugs that need the Cytochrome P450 liver detox pathway and what happens when that pathway is dysfunctional, as is frequent for those with toxic infections such as lyme and Cpn. Elevated porphyrins cause much damage. More about that here:
--------

http://www.cpnhelp.org/secondaryporphyria

SECONDARY PORPHYRIA

-----------------

http://flash.lymenet.org/ubb/ultimatebb.php/topic/1/91842

PORPHYRIA thread

============================

http://flash.lymenet.org/ubb/ultimatebb.php/topic/1/89790

Topic: NATURAL SLEEP - Links to articles & supplements
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[ 05-02-2010, 04:37 PM: Message edited by: Keebler ]

Posts: 48021 | From Tree House | Registered: Jul 2007  |  IP: Logged | Report this post to a Moderator
MazzyStar
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I used it for sleep, worked great. Im trying to taper off of it, but sometimes I need it.

--------------------
Lyme, Babs, Ehrlichia


www.mommalyme.com

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Camber
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quote:
Originally posted by Brandimc:
I used it for sleep, worked great. Im trying to taper off of it, but sometimes I need it.

i hear you about the toxicity, my main concern.

but when you take it periodically do you feel ****ty for days?

How do you handle other drugs?

Posts: 92 | From ri | Registered: Aug 2009  |  IP: Logged | Report this post to a Moderator
kday
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If you have anxiety from Lyme/Bartonella, be careful with anti-psychotics!

Geodon gave me several trips to the E.R. for IV tranquilizers. I've had a lot of scary experiences, but that was the scariest experience through this journey (or perhaps my life).

I had a practitioner teach me how to muscle test. For the heck of it, I muscle tested the Geodon last night, and it tested very bad. I had a sample of Zyprexa, so I muscle tested that, and suprisingly, it was much worse. Glad I never took it.

Posts: 967 | From A deserted island without internet access | Registered: Sep 2009  |  IP: Logged | Report this post to a Moderator
Camber
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my chiropracter muscle tests me, i dont know how to do it. Is there a u tube on it or could you explain how someone can do it to me.

i was given zyprexa in the hospital once, but i was so phycostic from not sleeping and being freaked out that i was in there..( before i knew i had lyme)

that i just remember sleeping for awhile and feeling out of it so its hard to gage.

i do need a good nights rest though. As i missed a few days of sleep accumilitiely in the past week.. and in a new country.

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Keebler
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Most sleep drugs actually work against us in the long run. Have you gotten some of the herbal remedies suggested in the Sleep Thread? Is your B-6 intact adequate? B-5, too?

Is your adrenal support in place? Exhausted adrenal function will make sleep nearly impossible, even with crushing fatigue.

I'm not sure what country you are in but most countries have these available. Also remember that it takes at least 3 weeks for the body to acclimate to time change. There are ways to work with that. Melatonin helps many with this.

You might consider getting a massage or seeing an certified herbalist if you can find one who has good recommendations from trusted local connections.
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Posts: 48021 | From Tree House | Registered: Jul 2007  |  IP: Logged | Report this post to a Moderator
   

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