lyme in Putnam
Frequent Contributor (1K+ posts)
Member # 11561
posted
I did flagyl for a week . My doc took me off and added mino and iv zithro 2x a week plus my usual rocephin. Sat I restarted iv zithro yesterday was bad,but today was mentally the worst. Could flagyl have lingering effects . My doc wants to do this again after a week of mino. Thanks
-------------------- He took u to it, He'll you through Posts: 2837 | From NE. | Registered: Apr 2007
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TF
Frequent Contributor (5K+ posts)
Member # 14183
posted
I think that each time you start up the zith again, you are herxing. You are getting sick 2 days after starting a "new" med. That, to me, says "herx."
When my doc added flagyl to the antibiotic I was used to taking, I herxed on the second or third day. That is the normal amount of time it takes to herx.
So, when you get sick, look back to two or 3 days before and ask, "What new thing did I do starting on that date?" That will give you the answer as to what is "making you sick" as they call it.
Here's where Burrascano says it takes 2 to 3 days:
"Several days after the onset of appropriate antibiotic therapy, symptoms often flare due to lysis of the spirochetes with release of increased amount of antigenic material and possibly bacterial toxins. This is referred to as a Jarisch Herxheimer-like reaction. Because it takes 48 to 72 hours of therapy to initiate bacterial killing, the Herxheimer reaction is therefore delayed. This is unlike syphilis, in which these reactions can occur within hours." p. 17
48 hours is 2 days and 72 hours is 3 days.
Posts: 9931 | From Maryland | Registered: Dec 2007
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sutherngrl
Frequent Contributor (1K+ posts)
Member # 16270
posted
Not sure what kind of lingering effects you are talking about. I took Flagyl 1 months straight with no lingering effects.
I agree that maybe the zith is causing a herx.
Posts: 4035 | From Mississippi | Registered: Jul 2008
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lyme in Putnam
Frequent Contributor (1K+ posts)
Member # 11561
posted
Thanks for answering me. Doing IV zith 2 days a week, other orals. restarted mino again, flagyl out. Feel good.
-------------------- He took u to it, He'll you through Posts: 2837 | From NE. | Registered: Apr 2007
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posted
Conversely if one takes abx and within 2-3 days with no herx, is that a confirmation that the person has no Lyme? I am still confused with this.
Posts: 822 | From midwest | Registered: Apr 2009
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TF
Frequent Contributor (5K+ posts)
Member # 14183
posted
wtl, the converse does not hold true.
I took antibiotics for 2 years without a herx. But, I was just taking one med at a time.
I had a lot of improvement in those 2 years without herxes. (I definitely had lyme disease for those 2 years--positive through LabCorp and all the symptoms.)
When I switched to a doc who treated me with high-dose amoxi (which I had been taking) AND added flagyl, I had my first herx.
So, evidently if we just kill off smaller doses of germs that our body can handle, no herx.
When we kill large amounts that we cannot get rid of right away, we have the herx. As Burrascano says, it occurs when there is an "INCREASED amount of antigenetic material and possibly bacterial toxins."
Know also that herxes are not just occurring in people being treated for lyme disease. They occur in other diseases also.
Wikipedia lists typhoid fever, syphilis and other diseases (including spirochetal infections and babs and bart) as causing herxes:
posted
Thank you, TF. My wife had seen the doctor you recommended. I will PM you now to let you know how it went.
Sorry for stealing the thread for a brief moment. I was just dying to ask the question.
Posts: 822 | From midwest | Registered: Apr 2009
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