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» LymeNet Flash » Questions and Discussion » Medical Questions » Cross reacting antibodies to lyme Elisa test-

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Author Topic: Cross reacting antibodies to lyme Elisa test-
rosespetalzzz
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Member # 26358

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I am trying to find information on what antibodies/autoimmune/related diseases can cross react with the lyme elisa test.

I am trying to make heads or tails of whats going on w me.

I had lyme, 2.07 elisa, 2igm, 7igg, treated, failed, 1igm, 7igg, + spinal tap- IV antibiotics.
Been holdign my own since with a few pitfalls but no antibiotics since 2002.

Current illness and severe lyme like body pains and exhaustion sought out another series of lyme tests. now my elisa is 6.80, and my IGM totally negative- no bands- and my IGG is 5 bands. Referring back to my old tests of 7IGG, they co-incide yet I've lost 2 bands but am still cdc positive.

All other b/w normal except elevated lymphocytes% up some, no inflammation- negative c reactivce protien, normal sed rate. had normal brain mri few months ago for other reasons, but good to know its normal!

Who knows what cross reacts w lyme elisa to make mine so freakishly high- IF its not lyme related?

Gotta play devils advocate always- so I need some reasearch and stuff to read- who knows?? anyone? thanks.

Posts: 11 | From NJ | Registered: Jun 2010  |  IP: Logged | Report this post to a Moderator
Tincup
Honored Contributor (10K+ posts)
Member # 5829

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Hey there..

I can't answer your questions as you have asked them... but here are some thoughts to consider.

What you describe seems normal for Lyme that was treated but not adequately. A "relapse" if you will, and/or combined with a new exposure.

Your ELISA being high means your body IS fighting the Lyme.. it is trying at least. That is a good sign.

Your IgM being "negative"... you must realize first of all they only tested a small amount of blood. The past or new exposure might not have been picked up on any given day... and/or...

The IgM can be negative if you've had Lyme for a good while... or negative for no reason at all. Luck of the draw.

The IgG is normally positive for folks who have had active Lyme for a year or more. % or 7 bands.. makes no difference.

Keep in mind 75% of folks are missed using the testing method you are using... so you are fortunate to have positive results leading you in the right direction.

You could have ten more tests ... for example, one weekly.. and get many different results with each test.

The IMPORTANT point here is the tests show you have Lyme, you have a history of Lyme and you have the symptoms to match.

If it looks like a skunk, smells like a skunk, it most likely IS a skunk.

You may want to check out some of the coinfections while researching.

Go to www.MarylandLyme.com

Click on the Tick Borne Disease link on the left sidebar and check them out. Maybe it will give you some ideas?

Hope that helps and remember this is only my opinion and I am not a doctor.

[Big Grin]

--------------------
www.TreatTheBite.com
www.DrJonesKids.org
www.MarylandLyme.org
www.LymeDoc.org

Posts: 20353 | From The Moon | Registered: Jun 2004  |  IP: Logged | Report this post to a Moderator
   

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