Candida infections are the fourth most common cause of nosocomial blood stream infections and are
associated with a significant mortality. Delays in antifungal therapy have been associated with
increased hospital costs of over US$6,000 per patient and overall mortality...
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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posted
It says it only helps lessen the number of mortalities, not improvement in the condition.
-- "There were no differences in duration of candidemia , antifungal therapy or Candida species between the groups. Statins were associated with lower mortality on bivariable and multivariable analyses compared to controls; although, in the latter the protective effect lacked statistical signficance." ---
In my opinion, statins are way overused and cause more harm than good when it comes to cardiac issues.
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96223 | From Texas | Registered: Feb 2001
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bcb1200
Frequent Contributor (1K+ posts)
Member # 25745
posted
Just so everyone is clear..the statin's referenced here are the cholesterol lowering drugs (i.e. lipitor, etc)
It is not Nystatin and other antifungals.
-------------------- Bite date ? 2/10 symptoms began 5/10 dx'd, after 3 months numerous test and doctors
IgM Igenex +/CDC + + 23/25, 30, 31, 34, 41, 83/93
Currently on:
Currently at around 95% +/- most days. Posts: 3134 | From Massachusetts | Registered: May 2010
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-------------------- long road since 2010 abx got me over the hump diet, detox, and herbs have got me to heal Posts: 174 | From CT | Registered: Jan 2010
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
I thought it was very interesting on many fronts.
One people should be aware of the consequences of no prevention,
and 2- One explanation of this effect is that statins in animal models have shown to reduce inflammatory markers, in particular the release of cytokines and cytotoxic effects of neutrophils.---
could this finding be taken into consideration in people that are on them in testing for markers in Lyme, and as others pointed out.
In heart problems it could be that because of reduced inflammatory markers
more cases of infection could be brought to light if they knew about these findings....
http://www.journals.uchicago.edu/doi/abs/10.1086/653675 Background.Blood culture-negative endocarditis (BCNE) may account for up to 31% of all cases of endocarditis. Methods.We used a prospective, multimodal strategy incorporating serological, molecular, and ...histopathological assays to investigate specimens from 819 patients suspected of having BCNE. Results.Diagnosis of endocarditis was first ruled out for 60 patients. Among 759 patients with BCNE, a causative microorganism was identified in 62.7%, and a noninfective etiology in 2.5%.
Thanks all. If these drugs do in fact reduce inflammatory markers. Maybe there are a lot more cases that could be found....
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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posted
Yes, statins reduce inflammation. That is one reason they use them for heart patients.
But what do you mean that they would help Lyme patients' tests come back positive? Is that what you said??
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96223 | From Texas | Registered: Feb 2001
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
No Lymetoo---I am saying the Statins may prevent diagnosis by suppressing the markers....
And since so many people take them they should consider this finding now.
It would be nice if they would clarify if the suppression of the markers can be measured.
If they could avg. the suppression they could automatically add to the tests to say these patients are infected...I know need more money.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- interesting about the masking.
Stress (and the resultant high cortisol) is one major cause of high serum cholesterol. Whether that stress is from infection, endocrine dysfunction or other stressors, rather than statins, if we worked at finding the CAUSE, my guess is no one would need statin drugs that carry such serious side-effects.
This book explains how high cortisol from infection causes high cholesterol, etc.:
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