posted
Yes. We need to take D3 to help our immune systems.
I'm tested almost monthly for it.... that important to my LLMD.
-------------------- Lyme, Babs, Fry Bug..... Whatever it is, may a treatment be discovered to make us all whole again! Posts: 941 | From AZ-MT | Registered: Oct 2004
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posted
i just posted about mine being borderline and now high........wonder why it affects vit D....
-------------------- Oct 09 Positive CDC Western Blot Jan 10 Positive Babesia Duncani Jan 10 Cd57 28 Mar 10 EBV, IgM, IgG HHV-6 IgG Posts: 739 | From NC | Registered: Oct 2009
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TF
Frequent Contributor (5K+ posts)
Member # 14183
posted
Here is an article that calls low vitamin D levels among Americans a "growing epidemic."
More and more people are being told by their doctors to take vitamin D supplements since they test low. All of these people don't have lyme. My husband is one of them. I am another. (I got rid of lyme and coinfections over 5 years ago.)
So, low vit D could be linked to people avoiding the sun, poor diet, etc. The vitamin D level of Americans is evidently declining. I don't think they figured out why yet.
In my research, I have read that as people age, their skin is not as efficient at converting sunlight to vit D, so their vit D levels go down. I believe that explains it for many people. But, I know I no longer sunbathe either, so I get very little sun compared to when I loved going to the beach and swimming pools all the time.
If you are avoiding the sun, that can be enough to make your vit D go too low.
Posts: 9931 | From Maryland | Registered: Dec 2007
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posted
My doc was saying it's because the inflammation that the Lyme's provokes lower Vit-D levels.
Posts: 131 | From PA | Registered: Aug 2007
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lymie_in_md
Frequent Contributor (1K+ posts)
Member # 14197
posted
there are many many minerals reduced due to lyme and company. Zinc and manganese are some of them. Also, using ABX weekens the flora in the body. The flora in the body produces most of the vitamin k2 (not k1 -- you can get k1 from plants) vitamin k2 is essential for utilizing vitamin D. So you could potentially be getting plenty of sun but still not convert the vitamin D. K2 is a very important vitamin, and you could easily draw the conclusion that k2 would drop with ABX use. But even if you don't have lyme, intestinal flora is always under attack.
I'll suggest, all those who take the supplement nattokinase made from natto (natto is fermented soybeans and the highest source of vitamin k2) feel much better. I believe in part to vitamin k2.
-------------------- Bob Posts: 2150 | From Maryland | Registered: Dec 2007
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posted
My Vit D was very low and I also started K2, just not sure how much I should take. I did notice i felt better.
Posts: 847 | From upstateNY | Registered: Dec 2007
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lymie_in_md
Frequent Contributor (1K+ posts)
Member # 14197
posted
How long ago, and are you taking a good fish oil for the vitamin A?
-------------------- Bob Posts: 2150 | From Maryland | Registered: Dec 2007
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posted
The topic of Vitamin D deficiency often comes up in threads; most will report improvements with supplementation, and if they don't notice improvement when taking supplements, they will notice deterioration when stopping. There are some however, who have a problem with the vitamin D cycle in their metabolism and will develop odd symptoms or worsen on vit D. Exactly what it does is a clue, though, and if properly interpreted can aid in correcty defining the path to recovery.
Posts: 442 | From Biddeford, ME | Registered: Nov 2007
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
http://www.ncbi.nlm.nih.gov/pubmed/20951967 2010 Oct 21 Cholesterol Lipids of Borrelia burgdorferi Form Lipid Rafts and Are Required for the Bactericidal Activity of a Complement-Independent Antibody.
Borrelia burgdorferi, the agent of Lyme disease, is unusual as it contains free cholesterol and cholesterol glycolipids.
It is also susceptible to complement-independent bactericidal antibodies, such as CB2, a monoclonal IgG1 against outer surface protein B (OspB).
We find that the bactericidal action of CB2 requires the presence of cholesterol glycolipids and cholesterol.
Ultrastructural, biochemical, and biophysical analysis revealed that the bacterial cholesterol glycolipids exist as lipid raft-like microdomains in the outer membrane of cultured and mouse-derived B. burgdorferi and in model membranes from B. burgdorferi lipids.
The order and size of the microdomains are temperature sensitive and correlate with the bactericidal activity of CB2.
This study demonstrates the existence of cholesterol-containing lipid raft-like microdomains in a prokaryote, and we suggest that the temperature dependence of B. burgdorferi lipid raft organization may have significant implications in the transmission cycle of the spirochetes which are exposed to a range of temperatures. --------------- Vitamin E is proven to reduce Cholesterol. Doc is right. We don't know much except we know we have to have Cholesterol to metabolize Vit. D...And by our deficiencies---I would say they need it more...
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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It is my assertion : vitamin D is very important but synergistically just as important is vitamin K2 -- not K1 -- K1 can be found in vegetables not the same thing. If you need to supplement vitamin D you need K2 as well. K2 is used to regulate calcium as well, an overload of calcium could go on to create inflammation as symptom of two much free floating calcium. You also need other supporting vitamins specifically vitamin A and E. A good fish oil might help.
from the link above:
Abstract The nuclear receptor steroid and xenobiotic receptor (SXR) is a transcriptional regulator activated by various biological and xenobiotic substances. We have recently shown that SXR is expressed in bone and that this receptor is critical for bone metabolism, particularly in osteoblastic cells. Vitamin K2, one of the critical nutrients in bone metabolism, has been demonstrated that it is a potent SXR agonist and modulates the expression of various bone-related genes in osteoblastic cells. Using microarray analysis, we identified novel SXR target genes that were activated by vitamin K2 in osteoblastic cells. Among them, a small leucine-rich repeat proteoglycan, tsukushi, has been shown to contribute to collagen accumulation, and the protein may interact with another vitamin K2-inducible SXR target, matrilin-2, a member of the matrilin family that functions as collagen adaptors. Besides functioning as a xenobiotic biosensor, our findings show that SXR is also a vitamin K2 target and an important transcriptional factor that regulates bone homeostasis in bone cells.
-------------------- Bob Posts: 2150 | From Maryland | Registered: Dec 2007
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METALLlC BLUE
Frequent Contributor (1K+ posts)
Member # 6628
posted
I get sick when I use Vitamin D supplements. It never improves either, even after 6 plus months. Being off Vitamin D makes me feel better, even though my numbers are supposedly low. My numbers were 25 Vit, (26), and 1,25 (66)
-------------------- I am not a physician, so do your own research to confirm any ideas given and then speak with a health care provider you trust.
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