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» LymeNet Flash » Questions and Discussion » Medical Questions » Dextrose in IV Meds a must????

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Author Topic: Dextrose in IV Meds a must????
mandy614
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I haven't posted here in a while. I generally just ask my dr but am getting conflicting opinions. I am doing an IV anti-fungal and they mixed it with DEXTROSE!!!!

Should the anti fungal be more strong than the small amt of sugar?

It's a 5% solution. Can someone tell me if this should be mixed with saline instead, or the molecular structure of sugar needs to bind to the med or something?

I really want to do this right this med is expensive. Thxs!!!

Posts: 348 | From maryland | Registered: Jul 2008  |  IP: Logged | Report this post to a Moderator
lou
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Try googling the information on this drug to see what the mixing instructions are. The package insert, if you have it, will also usually say what it is to be mixed with. Some libraries have the Physicians Desk Reference, a large tome that includes the info.

What is the anti-fungal?

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mandy614
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Hi Lou

I googled and got an assortment of options. I don't want sugar in my anti-fungal. Sending back I hope they'll take it as a return this stuff is crazy $$$.

In the first dose, I can tell my stomach is bloated and other unpleasant side effecst. I don't know if it's from the dextrose or meds.
thxs lou

oh med is IV Vfend [Smile]

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mandy614
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anyone seen docdave on here in a while?
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lou
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The reason I answered is because long ago, I was also given an IV med in dextrose and questioned it for the same reason. Requested saline instead.

There are definitely various options, but you are not required to have dextrose, for the reason you gave. Here is what the package insert says, for you and anyone else who is faced with this problem:

"The reconstituted solution can be diluted with:
9 mg/mL (0.9%) Sodium Chloride USP
Lactated Ringers USP
5% Dextrose and Lactated Ringers USP
5% Dextrose and 0.45% Sodium Chloride USP
5% Dextrose USP
5% Dextrose and 20 mEq Potassium Chloride USP
0.45% Sodium Chloride USP
5% Dextrose and 0.9% Sodium Chloride USP

The compatibility of VFEND I.V. with diluents other than those described above is unknown
(see Incompatibilities below)."

Anyone who gets a package insert should try to read it, maybe skipping the more technical parts. Especially read the interactions with other meds and herbs. This one, for instance, should not be taken with rifampin (taken by some lymies for bartonella). The little thing given by pharmacies typically does not have enough info.

Here is the package insert info for this drug. Easy to find if you google it.

http://www.pfizer.com/files/products/uspi_vfend.pdf

You were very smart to raise this issue.

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mandy614
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Thank you Lou.

They are telling me the dextrose is minimal at 5% and I would have to mix saline to the vfend myself. With dextrose it acts as a preservative.

They are aware of the lyme and sugar but are saying it's such a small amount..

They said I'm at greater risk for infection if I mix myself??? I've been mixing meds for a year now. I think I'm good.

So am ordering another 6 days and mixing saline myself.

Thxs again. I'm still confused...pe usual [Smile]

Posts: 348 | From maryland | Registered: Jul 2008  |  IP: Logged | Report this post to a Moderator
   

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