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» LymeNet Flash » Questions and Discussion » Medical Questions » Berkley finds B bissettii(UK) in CA ticks.

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Author Topic: Berkley finds B bissettii(UK) in CA ticks.
Pinelady
Frequent Contributor (5K+ posts)
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http://www.ncbi.nlm.nih.gov/pubmed/21177909

2010 Dec Department of Environmental Science, Policy and Management, University of California, Berkeley, California, USA.

Abstract
In North America, Lyme borreliosis (LB) is a tick-borne disease caused by infection with the spirochete Borrelia burgdorferi.

We studied the genetic diversity of LB spirochetes

... in north-coastal Californian residents.

Spirochete DNA was detected in 23.7% (27/114) of study subjects using a PCR protocol optimized for increased sensitivity in human sera.

Californians were most commonly infected with B. burgdorferi ospC genotype A, a globally widespread spirochete associated with high virulence in LB patients.

Sequence analysis of rrf-rrl and p66 loci in 11% (3/27) of PCR-positive study subjects revealed evidence of infection with an organism closely related to B. bissettii.
=================
This spirochete, heretofore associated with LB only in Europe,
=================
is widely distributed among ticks and wildlife in North America.

Further molecular testing of sera from residents in LB-endemic areas is warranted to enhance our understanding of the geographic distribution and frequency of occurrence of B. bissettii-like infections.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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