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» LymeNet Flash » Questions and Discussion » Medical Questions » babesia treatment, side effect question

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Author Topic: babesia treatment, side effect question
MichaelTampa
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I am about to start treatment for babesia, prescribed clindamycin plus malarone.

Burrascano guidelines say that in the past clindamycin plus quinine was used, but many had to stop with serious side effects. Does anyone know if those side effects were from the clindamycin or the quinine? Since I'm about to start clindamycin, I'm naturally wondering about that.

Burrascano's guidelines now say mepron/malarone plus azithromycin/clarithromycin/telithromycin is a good combo, maybe I'm close, but wondering why clindamycin.

Anyone else using malarone/clindamycin combination? What dose are others getting for malarone. I'm getting (at least starting with) 250mg twice a day.

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Tincup
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The quinine was the big problem. It caused hearing problems and other stuff.

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karenl
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Tincup,
I also have to start 250 mg malarone this week. What was the other stuff you got?
I have no babesia.

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beths
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Why are you taking malarone if you dont have babesia?
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karenl
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No idea, but my LLMD did prescribe it - probably as cyst buster.
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Maradona
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Quinine was more of the problem ,clinda has more frequent C.dif then other antibiotix.

What I'm seeing on your meds hope you are not thinking to take all this azithromycin/clarithromycin/telithromycin because they are antibiotics that work in the same way and same spot on baccteria ribosome .

Some books put them in the same group of antibiotics so you just will add toxicity to your body but take one off the 3 and add clindamycin.
Clindamycin is very good drug for some infections like helicobacter and campyllobacter,babesia and some others.

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MichaelTampa
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My doc is not putting me on just clindamycin and malarone. I was noting Burrascano mentioned a few choices for drugs with malarone, but clindamycin was not one of them. So, no, I wasn't planning on taking all those, just noticing it wasn't on Burrascano's list. They do all end in "mycin", so maybe they are similar enough, sounds like you are suggesting that as being in the same group.
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baileypup
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I have been on clindamycin IV for a year and a half with no side effects. The minute I added quinine, had the worst herx ever after one pill!!!

Tried quinine again, and felt like I had the flu for three days.

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Amanda
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Some of the LLMDs are finding treatment failure with the Mepron/zith. And both those drugs are expensive. (though malarone isn't that cheap either, its still not as $$$$ as Mepron).

So maybe your LLMD wants to try the less expensive stuff first. You could always ask the doctor why they choose your combo over mepron/zith

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