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» LymeNet Flash » Questions and Discussion » Medical Questions » Need Help with IGENEX results.

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Author Topic: Need Help with IGENEX results.
sonee123
LymeNet Contributor
Member # 18632

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This is a shame for me that i have been sick for almost 2 years and still don't know if i have a positive Lyme test or not.

Can someone help me figure this out please? I am doubting if i have Lyme now.

Igenex IGG result Negative
18,41,58+
34IND
22,23-25,28,30,31,39,45,66,73,83-93 all (-)

IGM

18,22,28,30,39,45,58,66,73,83-93 all (-)
41+
23-25,31,34,83-93 IND

I am so confused! I remember my LLMD doubted me after this test but i always responded to abx.

Do i have any influence of BB from these results or No?


Also i had a western blot done by Labcorp about 5 months before the Igenex one and the results were

IGG
P93,66,58,45,39,30,28,23,18, all Absent

P41 Present

The results for this was also negative.

Help please!

--------------------
May God Bless you, answer your prayers, relieve you of your pain and make you stronger than what you are today. Ameen.

Posts: 341 | From Columbia, MD | Registered: Jan 2009  |  IP: Logged | Report this post to a Moderator
BackinStOlaf
Frequent Contributor (1K+ posts)
Member # 23725

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That looks positive to me.

Most LLMD's see a IND result as positive.

You have band 18 which is specific for Lyme
No other disease would cause this to be positive
Look at Interpreting the Western Blot

http://www.lymefight.info/files/LymeTests.pdf

--------------------
First Symptom 9/09
Multiple docs, negative Labcorp test
LLMD: 1/10
Positive Igenex/CDC test
Treatment 2/10
2/10-8/10 Amox, ceftin, zith, flagyl
Currently: Bicillin, Minocycline, still dealing with severe breathing issues

 -

Posts: 1121 | From New York, New York | Registered: Dec 2009  |  IP: Logged | Report this post to a Moderator
t9im
Frequent Contributor (1K+ posts)
Member # 25489

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Also looks positive to me.

41 is more significant than what the main street medical MD's imply. It's specific to only a few spirochete bacteria and one can normally rule out the non lyme bacteria via symptoms.

My daughter has been sick for 20 months and she has never been positive on the WB. At best she had 3 positive bands but never at the same time plus a couple of indeterminates.

--------------------
Tim

Posts: 1111 | From Glastonbury, CT | Registered: Apr 2010  |  IP: Logged | Report this post to a Moderator
timaca
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Have you gotten tested for other pathogens? Such as other tick borne ones or viruses? See: http://chronicfatigue.stanford.edu/infections/

Best, Timaca

Posts: 2872 | From above 7,000 ft in a pine forest | Registered: Feb 2005  |  IP: Logged | Report this post to a Moderator
Fuel1212
LymeNet Contributor
Member # 29312

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I would say positive also. See below for more info on specific titers. Your immune system is compromised.

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have
this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

--------------------
IgM- 31,34,39,83-93 IND
IgM- 41+

IgG- 31,34,39,83-93 IND
IgG- 41++

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Lymetoo
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Member # 743

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If that was MY test I would expect to be treated for Lyme disease!

Dr C's Western Blot explanation:

http://tinyurl.com/ffn3x

--------------------
--Lymetutu--
Opinions, not medical advice!

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sonee123
LymeNet Contributor
Member # 18632

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I have been on treatment for about 2 years on and off.

Took abx for about 5 months straight and then took it maybe 5 days in a month.

Now i have a big attack of raging symptoms all at once.

--------------------
May God Bless you, answer your prayers, relieve you of your pain and make you stronger than what you are today. Ameen.

Posts: 341 | From Columbia, MD | Registered: Jan 2009  |  IP: Logged | Report this post to a Moderator
   

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