tricia386
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posted
So I testes Postive for Mycoplasma Pnem. Dont know much about this coinfection can anyone enlighten me??
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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tricia386
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I have no symptoms of it though??? So werid!
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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momlyme
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If the above link doesn't work, use this search in google and you will get several articles on the subject.
site:http://www.immed.org "mycoplasma pneumonia"
-------------------- May health be with you!
Toxic mold was suppressing our immune systems, causing extreme pain, brain fog and magnifying symptoms. Four days after moving out, the healing began. Posts: 2007 | From NY/VT Border | Registered: Aug 2010
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momintexas
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This can be a very stubborn infection to get rid of.
Here's some good info and links about it.
Immune Disruption
"Mycoplasmas can also disrupt the normal orchestration and organization of the host�s immune system. They can cause lymphocytes (white blood cells that bear the major responsibility of the immune system) to secrete inflammatory cytokines (proteins that facilitate cell-to-cell communication), which leads to swelling, inflammation and either stimulation or suppression of the immune system. "
"Mycoplasma are a group of microorganisms which are a cross between a virus and a bacteria. Together with Chlamydia and Rickettsia they make up a family of microorganisms known as Rickettsiae and Pararickettsiae. They are found everywhere, the hosts are usually rodents and the vectors are arthropods (insects with jointed legs) or airborne through dust. Rickettsial organisms have been found in ticks, lice, fleas, mites, meat, milk, stool and dust.
They are the smallest free living organisms. Like viruses, they are intracellular organisms but unlike viruses, they can reproduce outside cells. They lack a cell wall which makes them resistant to many antibiotics. They enter the body through skin, lungs or digestive system. They then spread through the bloodstream to infect vascular endothelium. They multiply within cells until numbers are so great that the cells burst. This then damages blood flow to multiple organs, hence the multitude of symptoms which may occur.
Research by Dr Cecile Jardin (a French surgeon now based in South Africa and specialising in the treatment of chronic fatigue) has shown that the most common symptoms of chronic mycoplasma type infections include:
Symptoms are caused by the release of 3 types of toxins into the blood:
1. Endocytokines that cause inflammation and pain. 2. Neurocytokines that produce neurological symptoms including the demyelinisation found in multiple sclerosis and psychiatric symptoms such as depression and anxiety. 3. Allergens causing allergies.
Mycoplasma infections can be occult. That means they can be asymptomatic and lie dormant until another bacteria, virus, parasite, stress or toxin activates it and causes the symptomatic phase.
Often these chronic conditions improve dramatically and even completely recover once the infection is identified and appropriately treated. In my opinion, everyone with the above conditions should be screened for chronic mycoplasma infection."
"Acute mycoplasma infections can be diagnosed by seeing an elevation in mycoplasma antibodies in a blood test. However, chronic infections often require specialised DNA testing (polymerase chain reaction). Clues to a persistent mycoplasma infection include an elevation in inflammatory markers like C-reactive protein, low white cell count, unexplained elevation of liver enzymes, elevated thyroid antibodies (in 28%) an elevated ESR, elevated rheumatoid factor, elevated antinuclear antibody and an elevated IgM antibody."
"Autoimmune conditions associated with Mycoplasmas include arthritis, Fibromyalgia, myositis, thyroid dysfunction (Hashimoto�s or Grave�s Diseases), and adrenal dysfunction, signs and symptoms of Lupus, Multiple Sclerosis, Lyme,and Lou Gehrig�s Disease.
The Mycoplasma organism has the capacity to invade cells, tissues and blood, producing systemic infections in numerous organ systems. According to Dr. Nicholson, it can penetrate the central and peripheral nervous system. Because it has the ability to damage the immune system by invading the natural killer cells (NK cells) of the lymphocytes, it weakens them, reduces their numbers, and renders them susceptible to viral infections, such as Human Herpes Virus 6 (HHV6), HHV7 or HHV8. It may also explain some of the environmentally sensitive responses that are seen with CFIDS and MCS.
Mycoplasma infection can trigger inflammatory cytokine over-production that is commonly seen in CFS/FMS. With the induction of CD-4+ helper cells of the immune system, an over production of cytokines such as Interleukin-1, Interleukin-6 and Tumor Necrosis Factor-alpha occurs. These elevated cytokines have been implicated in the development of many of the CFS/FMS symptoms, including neurological involvement. They can have specific or nonspecific stimulatory or suppressive effects on lymphocytes, as measured by B and T cell activation.
In addition, the Mycoplasma infection has immune-modulating effects, activating the hypothalamic-pituitary-adrenal axis. This can cause a cascade of limbic system symptoms characteristic of CFS/FMS."
"Due to the lack of a cell wall, all mycoplasmas are innately resistant to all beta-lactams and glycopeptides. Sulfonamides, trimethoprim, polymixins, nalidixic acid, and rifampin are also inactive. Linezolid is the prototype agent of the oxazolidinone class. These agents are much less active against M. pneumoniae than the other agents that inhibit protein synthesis (224). New quinolones such as moxifloxacin, gatifloxacin, garenoxacin, gemifloxacin, and sparfloxacin tend to have somewhat greater in vitro activity than older agents such as ciprofloxacin, ofloxacin, and levofloxacin, although MICs of all fluoroquinolones are severalfold higher than those of macrolides (224, 435-437). Fluoroquinolones have been shown to be bactericidal for M. pneumoniae, whereas macrolides and tetracyclines are primarily bacteriostatic"
posted
The above is a lot of good info - don't have anything to add,
except when I read your heading, I thought it said Mycoplasma Poem. Help! And wondered what THAT was about -
Posts: 13116 | From San Francisco | Registered: May 2006
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posted
Can you describe how high the igg and igm levels are in your tests?
-------------------- My biofilm film: www.whyamistillsick.com 2004 Mycoplasma Pneumonia 2006 Positive after 2 years of hell 2006-08 Marshall Protocol. Killed many bug species 2009 - Beating candida, doing better Lahey Clinic in Mass: what a racquet! Posts: 830 | From Mass. | Registered: Aug 2006
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tricia386
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posted
So how long does it take to clear infection and what meds?
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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momintexas
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Are you high IgG or IgM or both?
How long to clear is a million $ question. A chronic infection can take a very long time.
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tricia386
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im high in BOTH!!!
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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canefan17
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posted
Hard to differentiate between Babs and Myco
Posts: 5394 | From Houston, Tx | Registered: Aug 2009
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posted
Can you post your scores/results? Like how high is high???
PS.. Is your dr concerned about it?? What did he say?
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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tricia386
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posted
I was in the 1400 in one and 1100 in the other...
i just got the test back today and have to fax to my LLMD
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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posted
Myco is so much like lyme disease they're practically indistinguishable. They cause the same symptoms (even the facial palsy and rate of neurological disease!) and replicate equally as slowly. I wouldn't worry about it too much because most drugs that treat Lyme will inadventantly treat Mycoplasma as well. But your doctor will probably make sure of that, now! I'm positive too. On Zithro for Lyme but it treats myco. Was on Doxycycline 400mg for five months and it helped but didn't seem to knock it out, I got pleurisy twice after stopping. I think because it replicates slowly you have to treat it almost as long as you do Lyme disease.
Doxycycline is a great choice because it treats bartonella, myco, and Lyme. Won't eradicate them but it's a good place to start! Right now I'm on the Rifampin and Zithro combo.
-------------------- Myalgic encephalomyelitis, 2002 | Viral onset, following Hep B vaccine Lyme since '06 | Bartonella since '08 (cured) | Mycoplasma pneumoniae since '08 IGeneX: IgM 31IND 34IND 41+ | IgG 39IND 58+ 41+++ IgG deficiencies and MTHFR 677TT mutations Posts: 512 | From USA | Registered: Sep 2010
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posted
Gram negative bacteria can create infections that are similar to one another (e.g. Bb similar in presenting symptoms like mycoplasma pneumonia); given what they do to us humans if they are successful in avoiding our immune defenses and antibiotics. They can and do invade every part of the human body. Most gram negatives (if not all) form both mono and polymicrobial biofilm communities, which contribute to the myriad challenges of both diagnosis & treatment.
From what you describe, you have had this infection for some time, and it is still active (high titres of both igg and igm).
Btw, it could be a coinfection, or picked up in communities, the hospital, etc.
-------------------- My biofilm film: www.whyamistillsick.com 2004 Mycoplasma Pneumonia 2006 Positive after 2 years of hell 2006-08 Marshall Protocol. Killed many bug species 2009 - Beating candida, doing better Lahey Clinic in Mass: what a racquet! Posts: 830 | From Mass. | Registered: Aug 2006
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posted
I tested positive by quest. How high should my number be to know its activated?
Posts: 144 | From Pennsylvania | Registered: Jan 2011
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momintexas
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There should be a range on your test result. Do you have a copy of it?
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posted
My mycoplasma Igg wa 5 which is positive, but my igm was 77 which is very negative. Does that mean I have this? It sounds worse than lyme. Has anyone gotten better from this? In the info above it sounds like it causes fibro and cfs. I am very confused.
Posts: 144 | From Pennsylvania | Registered: Jan 2011
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momintexas
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posted
chootik - I have read Biaxin and Zith but I am hearing more and more stories from parents who say zith is not helping.
Sandim - there should be a range on your test result as far as what #'s are considered positive.
If your IgG isn't very high then some Dr's wont really look that hard into it.
What has your Dr told you?
Posts: 1408 | From Tx | Registered: Nov 2009
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tricia386
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posted
MY Igg is 1456 IGM 1831
Yikes!
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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posted
I have/had myco pneu also...4mo of doxy and 2 rounds of Zith plus 2mo high amox. did nothing. I have had it for years, and still do. As far as I can tel, I do not have any major symptoms of it NOW, but who knows what role it plays...
My Dr. does not seem to be al that concerned with it as he feels that my immune system is simply so wonky I am ust making too many antibodies to alot of things that may not ACTUALLY be issues. He did do 2 rounds of Zith, like I said, but he isn't doing anything else and for now I am ok with that also...
Do you *feel* like you are sick with it?
Posts: 206 | From In the shadow of a mountain | Registered: Feb 2011
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tricia386
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posted
What are the symptoms???
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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momlyme
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posted
I was told (in 1995) that I had "walking pneumonia" and pleurisy. I hospitalized because I was throwing up blood. I was given the z-pack... which was 5 days of abx. I have never had abx since.
Is "walking pneumonia" the same thing as Mycoplasma Pneumonia?
The hospital is long since closed down and I can't seem to track down the medical records.
My son tested positive for Mycoplasma Pneumonia... is this another infection that can be passed from mother to child?
I have read myco. pneu. is airborn also?
Anyone know if dogs can have this and pass it in a dog bite?
-------------------- May health be with you!
Toxic mold was suppressing our immune systems, causing extreme pain, brain fog and magnifying symptoms. Four days after moving out, the healing began. Posts: 2007 | From NY/VT Border | Registered: Aug 2010
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momintexas
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Yes, it is absolutely airborne - it's highly contagious and is very common to find in public places, schools etc.
Please read below from Dr N's website:
ANTIBIOTIC THERAPY FOR CO-INFECTIONS OF CHLAYMDIA AND MYCOPLASMA
"Patients with coinfections of Chlamydia plus Mycoplasma species may not tolerate the initial use of Amoxicillin. The reason for this is that the mycoplasmal infections are not susceptible to amoxicillin, and other antibiotics are recommended, such as doxycycline or minocycline, azithromycin and clarithromycin [1]. These are used singly at first, similar to the amoxicillin regimen above. For Mycoplasma and Chlamydia species infections, 6 months [no break] therapy, then 6-week on 2-week off antibiotic cycles (doxycycline, ciprofloxacin, azithromycin, minocycline, clarithromycin or similar, p.o., work best as capsules without starch fillers). Some patients benefit from combinations of antibiotics, such as doxycycline plus azithromycin or ciprofloxacin, especially if there are limited responses to either antibiotic alone."
Posts: 1408 | From Tx | Registered: Nov 2009
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tricia386
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posted
ugh one more thing to worry about!
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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tricia386
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ugh one more thing to worry about!
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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tricia386
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posted
What are the symptoms of MYCO?
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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tricia386
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posted
I wonder if this could be causing my hives?
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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posted
Funny you should mention that, because it definitely gave me hives! And I don't have an allergy one! I would always get hives a week or two before I got the pleurisy. It was one of my warning signs. I suspect it's because of the elevated eosinophils (an immune cell), which are responsible for fighting parasitic-like infections as well as allergies. This is a clinically significant sign of mycoplasma pneumonia (and bartonella, too) so maybe you can check your recent bloodwork.
little olive
-------------------- Myalgic encephalomyelitis, 2002 | Viral onset, following Hep B vaccine Lyme since '06 | Bartonella since '08 (cured) | Mycoplasma pneumoniae since '08 IGeneX: IgM 31IND 34IND 41+ | IgG 39IND 58+ 41+++ IgG deficiencies and MTHFR 677TT mutations Posts: 512 | From USA | Registered: Sep 2010
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posted
I had hives for weeks, but we assumed that it had to do with an allergy to Mucinex and Penicillan! I am still struggling with after effects of Myco although pneumonia-like symptoms are done.
I'm doing Byron White's Myco A -- just started -- kicking ma patooties!
Good luck,
wiserforit2
Posts: 273 | From Banks of the Hudson | Registered: Nov 2008
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tricia386
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posted
so wait! your hives were caused by myco??? `
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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posted
I honestly don't know if it was the Myco Pneumonia or the Mucinex or the Penicillan, but I stopped all and had hives off and on for almost 6-8 weeks -- which was how long it took to get rid of the cough too. I did two Z-Pacs from a duck. Afterwards, I went downhill with arthritic symptoms and fatigue, which I've been battling since last October. Feels worse than my old Lyme symptoms. I kept thinking it was just detoxing from AI, until I had a Myco test that came up positive as well as muscle testing coming up positive too. Now the Byron White formula is confirming my suspicions about Mycoplasma.
Posts: 273 | From Banks of the Hudson | Registered: Nov 2008
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posted
For mycoplasma and chlamydia pneumoniae information research Prof. Garth L. Nicholson and the lab, Viral Immune Pathologies.
I had chlamydia pneumoniae and was on Doxy, Zithromax 3 times a week and Tinidazole. Mine is gone.
I was treated for 9 months, but I really don't know when the infection was gone. I may have been treated longer than necessary.
Posts: 44 | From New York | Registered: Feb 2011
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posted
You are very lucky, Suzy50, to have responded well to the abx. I can no longer take abx after five years on them constantly. I have needed to follow an alternative regime to address most things. But, I thank you for mentioning Prof. Nicholson.
Best, wiserforit2
Posts: 273 | From Banks of the Hudson | Registered: Nov 2008
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tricia386
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posted
So how long did it take your hives to go away w/treatment
-------------------- Lyme activated in April 2010 by gardasil vaccine. DX: Lyme,Babs,Myco,Bart 11/10 Treatment Started: 3/28/11 Posts: 1752 | From Albany, NY | Registered: Dec 2010
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CherylSue
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posted
up
Posts: 1954 | From Illinois | Registered: Aug 2007
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There is much talk of mycoplasma infection on www.roadback.org, for those with autoimmune components.
There are many kinds of mycoplasma, not just mycoplasma pne. Dr. Nicholson has researched mycoplasma fermentans, and has done extensive studies with CFS and Gulf War Syndrome.
Here's a list of antibiotic suseptibilities from the roadback website:
Susceptibilities of common mycoplasma strains to antibiotics
S=susceptible; R=resistant; M=marginal response; S/R=mixed response M. pneumoniae (respiratory tract) S minocycline S erythromycin S doxycycline R cephalosporins S difloxacin S clarithromycin S azithromycin S/R clindamycin S/R ciprofloxacin M hominis (genitourinary tract) S minocycline R erythromycin S doxycycline S cephalosporins M difloxacin R clarithromycin S azithromycin S clindamycin S ciprofloxacin U urealticum (genitourinary tract) S minocycline S erythromycin S doxycycline S temafloxacin S/R difloxacin S/R clarithromycin S/R azithromycin R clindamycin S/R ciprofloxacin M fermentans (incognitis) (genito-urinary tract & oropharynx) S minocycline R erythromycin S doxycycline S temafloxacin ? difloxacin ? clarithromycin ? azithromycin S clindamycin S ciprofloxacin
Some mycoplasmas, such as M. hominis and U urealticum are often found together and they each are resistant to the antibiotic which eliminates the other.
Usual colony site locations can also be helpful in choosing an effective dose of antibiotic as some sites take a higher dose than others.
Commercial mycoplasma test kits often give a false positive result and are not recommended.
A negative test is not unusual at the start of treatment. A second test approximately 4 weeks later often gives a positive result.
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