Single IgG titers of 1:64 and greater against Borrelia hermsii are considered presumptive evidence of infection by Borrelia.
A fourfold or greater change in titer between acute and convalescent sera provides evidence of recent or current infection.
Acute sera generally show specific IgM titers > or = to 1:16 while patients with manifestations of later stages of disease display elevated IgG titers only.
Crossreactivity is shown with other Borrelia species and Treponema; therefore, positive specimens should be assayed in parallel against these antigens when possible to identify the specific species causing infection.
Posts: 200 | From Nevada | Registered: Dec 2008
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/