Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
It appears Bb can be a trigger for Parkinson's - ultimately - though other pathogens could do the same.
(Given the speed of Michael J. Fox's onset of PD, I suspect perhaps a virus can do the same faster.)
The emerging role of eicosapentaenoic acid in Parkinson�s Disease
January 18th, 2011
It is well established that DHA is the primary structural omega-3 in the brain, and it is therefore important to prevent DHA loss.
However, because DHA is the most unstable of the long chain omega-3′s, the products of lipid peroxidation derived from DHA supplementation may actually counteract the advantage of DHA in protection against Parkinson�s disease.
In contrast, EPA levels within the brain are low in comparison to that of DHA, but this fatty acid plays an important neuroactive role and may have benefits over DHA in treating Parkinson�s disease.
Firstly, EPA is a natural precursor to the synthesis of DHA and also blocks the production of an enzyme called PLA2, which releases DHA from cell membranes.
By blocking this enzyme, EPA therefore helps to maintain cell membrane integrity within the brain.
EPA is also a potent anti-inflammatory, and, unlike DHA, can directly inhibit the production of inflammatory products from the omega-6 arachidonic acid, which themselves are known to contribute to the progression of Parkinson�s.
EPA, again preferentially over DHA, is also involved in myelinogenesis by stimulating the production of several myelin proteins which are thought to be key to the inhibition of loss of myelin and therefore brain atrophy.3,4
More recently, EPA has been suggested to regulate dopamine turnover and down-regulate genes involved in neuronal cell death pathways, thus further supporting a beneficial role for ethyl-EPA supplementation as both a preventative and therapeutic tool in neurodegenerative disorders.5
DHA is structural - it is a component of our cell membranes...a LOT...esp. our brain
Infant formulas add this Omega 3 nutrient.
EPA is functional - it reduces inflammation, big-time.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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James1979
Unregistered
posted
Does this mean that supplementing with fish oils would help prevent Parkinson's? If so, do the statistics show that Parkinson's has a lower incidence among populations that eat plenty of fish?
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My mom has Parkinson's and I have Lyme. I wonder if Lyme had anything to do with her Parkinsons?? She was also a smoker and was very anxious throughout her life, which is a big factor in getting Parkinsons.
James I would think your conclusion would be right. The question is how much EPA?
Posts: 247 | From Ca | Registered: Feb 2007
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
The makers of OmegaBrite suggest 3 capsules per day all at once with a meal.
That product is very very unique and is NOT THE SAME as Krill oil!
Kid's versions of OmegaBrite are available.
It will take TIME...months.
You know this disease takes time to cure and reverse the damage, right?
OmegaBrite is avail. only over the internet. I have no tie to this product, but it has really helped my son and brought my sis' (lyme) CRP down to its lowest level in years.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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My mom has Parkinsons now! I wonder if it has anything with the lyme??
I'm going to get her tested. By any chance did you father have really bad anxiety? My mom has that and muscle stiffness. She doesn't have the shakes too much.
Posts: 247 | From Ca | Registered: Feb 2007
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