LymeNet Flash: Explain Igenex Bart. IGM/IGG please

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»	LymeNet Flash » Questions and Discussion » Medical Questions » Explain Igenex Bart. IGM/IGG please - Decline times?

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Topic: Explain Igenex Bart. IGM/IGG please - Decline times?

susank
Frequent Contributor (1K+ posts)
Member # 22150

posted

I still cannot make sense of the revised interpretation as of 2011.
-----------
As stated:
IGM <20 negative IGG <40 negative

IGM 20 or IGG 40 to 160
May or may not indicate active infection. In patients with previously high titers, such titers indicate resolving infection.

IGM or IGG >160
Suggests active infection with B. Henselae.
***Titers rise during the first 2 to 4 weeks of illness and decline over 6 to 12 months***.

*** mine to highlight
----------

I wish Igenex had separated the interpretation for IGM vs IGG.

It is understood that most illnesses the IGM decline or disappear after weeks or within a few months.

What about IGG?
Who knows if anyone had previously high titers by the time they first test?

***
The "rise and decline" interpretion makes sense for IGM. But I don't think so for IGG.

So what is one to think of a result of:
IGM <20 and
IGG 40?

Since 2011 how many here have gotten a result of IGG 40? How many with IGG higher than 40?

--------------------
Pos.Bb culture 2012
Labcorp - no bands ever
Igenex - Neg. 4 times
With overall bands:
IGM 18,28,41,66 IND: 23-25,34,39
IGG 41,58 IND: 39
Bart H IGG 40

Posts: 1613 | From Texas | Registered: Aug 2009 | IP: Logged |

Lymetoo
Moderator
Member # 743

posted

quote:
Originally posted by susank:

It is understood that most illnesses the IGM decline or disappear after weeks or within a few months.

-
MOST illnesses... but NOT in Lyme disease.

I have not seen the new test.

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96222 | From Texas | Registered: Feb 2001 | IP: Logged |

jackie81
LymeNet Contributor
Member # 27031

posted

I got IGG 1:40 and was told its a low positive bc its right on the cutoff

Posts: 574 | From Out there somewhere | Registered: Jul 2010 | IP: Logged |

susank
Frequent Contributor (1K+ posts)
Member # 22150

posted

My questions are about Bart.

Since 2011 were the interpretations for the other co's revised? Seems like they had a different explanation/cut-off then Bart in the past.

Pre 2011 < or = 1:40 was said to be negative for Bart. on IGG.

--------------------
Pos.Bb culture 2012
Labcorp - no bands ever
Igenex - Neg. 4 times
With overall bands:
IGM 18,28,41,66 IND: 23-25,34,39
IGG 41,58 IND: 39
Bart H IGG 40

Posts: 1613 | From Texas | Registered: Aug 2009 | IP: Logged |

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