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» LymeNet Flash » Questions and Discussion » Medical Questions » LACTIC ACIDOSIS SYNDROME AND LYME

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Author Topic: LACTIC ACIDOSIS SYNDROME AND LYME
Al
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.
It is well known that Borrelia create an acid environment in the body. Lactic acidosis seems to be involved .
Dr Cheney (CFS Researcher) has found Lactic acid in the brains of people with CFS. The brain should have 0 lactic acid, Zero !
Note the symptoms below .These symptoms fit well in the lyme picture.
Are the symptoms of lyme actually lactic acidosis syndrome caused by lyme?


The symptoms/signs of lactic acidosis syndrome can be very vague, nonspecific and easily mis-diagnosed. This requires that you and your physician need to be aware of the existence of this syndrome in order to diagnose this early. Symptoms described include nausea, vomiting, abdominal pain, weight loss, malaise, hyperventilation/(dyspnea (air hunger), liver dysfunction, arrhythmias, cyanosis, cold extremities, and lethargy. Perhaps a useful way of looking at these symptoms may be to think of them as those related to liver dysfunction [increased liver function tests, enlarged liver, nausea and vomiting, abdominal pain], those due to making the entire organism chronically ill [malaise, lethargy, weight loss] and symptoms that ensue when the acid-base system is substantially disturbed [hypotension, coma or stupor, hyperventilation/dyspnea as the body attempts to correct the acidosis by exhaling more CO2 in order to normalize the pH in the blood, and arrhythmia due to dysfunction of the cardiac conduction system from the acidosis].

[ 13. September 2007, 12:46 AM: Message edited by: Al ]

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johnnyb
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Very interesting.

I continually demonstrate early lactic acidosis (metabolic acidosis / crossing over the anaerobic threshold early) on a cardiopulmonary stress test, with no explanation (all heart tests, including catheterization are NORMAL).

Finally some correlation with lyme.

- JB

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dontlikeliver
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Interesting...but what would be the treatment for that?
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Itsy_bitsyone
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Where is that from, if you do not mind me asking?

People with lactic acidosis (which is the main function in rigor mortis after death) normally do not live for more than 48 hours without treatment.

What is this syndrome?

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Al
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.
I just stumbled on this connection so I don't have any answers yet. I assume that eliminating the infection would allow the body to correct itself. Maybe correcting this condition would be the key to successful treatment.
Hypoxia is implicated in excess lactic acid and this could explain brain fog in lyme because the brain is not getting enough blood (oxygen) creating chronic hypoxia in the brain. In a state of lactic acidosis the body burns sugar instead of oxygen, This may account for the sugar cravings so common with lyme.
My interest stemmed from a test for Citrate by my Dr. ; My Citrate was the lowest he had ever seen. Citrate is an alkalizing buffer in the body and I was put on Sodium Bicarbonate 3xday to try to stabilize the acid environment.
I just had a test for Lactic acid yesterday (Blood test) and it will be interesting to see what the results are.
I really think I'm on to something here but I don't know yet what this would mean regarding treatment. Maybe lactic acid levels could be useful in monitoring treatment also.
If anyone has a contact for Dr. Donta in Ma.
let me know because he was trying to alkalize the body in his lyme treatment but I don't think he made a connection with Lactic acidosis syndrome.
Al

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shazdancer
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Very interesting, Al. Lactic acid is also a byproduct of exercising, causing muscle soreness. I have noticed in myself becoming overly sore and draggy after exercising when sick, especially flaring two days after, which is unusual. An overproduction of lactic acid could explain it.

Let us know what you find.

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Truthfinder
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This is interesting, Al....

I have never heard of a Citrate Test and can't find it over at the LabTestsOnline website....

...is there perhaps another name for it that you know of?

Tracy

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Tracy
.... Prayers for the Lyme Community - every day at 6 p.m. Pacific Time and 9 p.m. Eastern Time � just take a few moments to say a prayer wherever you are�.

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Al
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This is very interesting because some bacteria utilize Citrate as their sole source of carbon.
I made the mental leap to Borrelia but have no information on this.

.Source, AUSTIN College.
Simmons citrate agar tests the ability of organisms to utilize citrate as a carbon source. Simmons citrate agar contains sodium citrate as the sole source of carbon, ammonium dihydrogen phosphate as the sole source of nitrogen, other nutrients, and the pH indicator bromthymol blue. This test is part of the IMViC tests and is helpful in differentiating the Enterobacteriaceae.

Organisms which can utilize citrate as their sole carbon source use the enzyme citrase or citrate-permease to transport the citrate into the cell. These organisms also convert the ammonium dihydrogen phosphate to ammonia and ammonium hydroxide, which creates an alkaline environment in the medium. At pH 7.5 or above, bromthymol blue turns royal blue. At a neutral pH, bromthymol blue is green, as evidenced by the uninoculated media.

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Monica922
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When I was in the hospital..the last one...unreal...anyway they did puncture my artery and test for this because my initial blood work indicated the same. I was not familiar with this one...we all heard MS, connective tissue disorder, lupus, etc..but this was a new one for me.
By the way, an artery puncture is even more fun than a regular blood test. Curious that it did go away with the artery puncture test? Maybe it comes and goes...like most of the crud on our blood tests. It is very interesting though.

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CaliforniaLyme
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Babesiosis makes the body acidic and can cause acidosis.

TBE viruses need acid environments to be activated!!!!!!!!!!!

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Tincup
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Good info!

And what we do for the lactic acid is to drink lemon water.

Weight lifters and runners often do this to help dilute and remove the lactic acid after exercising.

Don't ask me the chemical junk and stuff.. I only have been suggesting drinking lemon in your water cause as a weight lifter and a forced olympic traineee (YEARS ago).. it was what was used to help prevent the "burn" after a hard workout... which is how our muscles feel after doing even the slightest thing... like repeated strokes while brushing your hair.

Those who HAVE hair I mean.

[Cool]

So drink drink drink that lemon water and notice the difference.

[Big Grin]

Powdered L-Glutamine is also used to rebuild the tissues and muscles. Pharmacutical grade ONLY... with no additives. Can be bought in most health food stores.

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Monica922
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This is very interesting since I did test positive for Babesia in July and Oct. I am not being treated now for the Babesia. I am on IV Roceph 23 days and zith 9 days. The newest Babesia test before the drugs said IGM Babesia 1:40. LLMD thought it might have been treated effectively enough..maybe not!

I was on 3 weeks of mephron/zith in Oct. but then I took prednisone...yeah I know..insane....maybe it is back again with the Lyme...or going like a see-saw.

I do feel better cognitively but the neuropathy is still a joy!

Will they give you IV Rocephin, zith and mephron..or do they wait? Any ideas? Do you get resistant to mephron/zith?

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canefan17
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bump
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canefan17
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babesia related to acidosis?
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