Topic: When you pulse rocephin, can the 2 doses be taken back to back?
Rumigirl
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posted
Or is it better to take them spread apart as much as possible, as I was assuming? That is, when you are taking it twice a day for 4 days per week. I didn't think to ask the dr when I was there on Friday.
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TF
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You are to try to take each dose about 12 hours apart. You cannot take both doses together.
Posts: 9931 | From Maryland | Registered: Dec 2007
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TF
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Member # 14183
posted
Well, this is from page 16 of Burrascano:
"Treatment with ceftriaxone is dosed at 4 grams daily- given either as 2 grams IV twice daily, or 4 grams slowly once a day, four days in a row each week, usually for 14 or more weeks."
So, maybe you CAN take both doses together if you want to.
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Rumigirl
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Thank you, TF, straight from the "horse's mouth!" (No disrespect intended for the great Dr. B, of course). I didn't even think to look there.
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Hubby recently restarted IV rocephin -- the doc just said to do 2 grams twice a day and I never thought to ask about timing either. We are spacing it close to 12 hours apart.
The doc is using the Weisbren approach (the former IDSA doc who wrote the case study book) and hubby is NOT pulsing but doing the 4 grams daily 7 days per week. Actually the doc mentioned the possibility of increasing the dose to 6 grams daily. Have an appointment next week and will discuss this further as hubby is still running daily fevers of 100.0
I have the book on order, but for now the scrip is for 2 months at the current dose.
Bea Seibert
Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004
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Rumigirl
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Oh, Bea, I hope that his fevers break soon, and that things improve. What you guys have had to endure is beyond the pale. As someone said recently, you are so amazing. You never whine or complain. You just keep on trying to figure out what the next best steps are.
Interesting about the 2 grams daily 7 days a week regimen---and possibly going up to 6 grams. Did he already lose his gallbladder, or he is just doing ok anyway in that department? I lost mine, despite Actigall and umpteen Liver/Gallbladder Flushes (and lots and lots of other treatments to preserve it).
I'll be very interested to hear what comes of this regimen, and possibly upping it. Keep us posted. (I hope you see this).
Posts: 3771 | From around | Registered: Mar 2008
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posted
Most LLMD's don't like to be challenged with dosing but mine has me on 2 grams of rocephin once a day for 5 days each week, plus orals.
I started feeling better around the 3 month period but the past month has been lousy. I have a phone appt tomorrow and don't know how to bring up dosage again without ruffling feathers.
I had to switch my zith to morning because it was interfering with the muscle relaxers I take at night and causing a lot of arrhythmia's.
I found that out online. No one else, either the pharmacy or doctors figured that out.Switching to the am with that fixed that problem but now all meals pour out of me.
I can hardly eat anything without getting a stomach ache. I am always in the bathroom. So fatigue is much, much worse.
-------------------- Faithful
Just sharing my experience, I am not a doctor. Posts: 2682 | From Colorado | Registered: Oct 2009
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Rumigirl
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Hmmm, faithful, that is not a usual dosage at all. I had to do that in the past, but that was of necessity, because my gallbladder couldn't take rocephin any more frequently, in spite of Actigall. Point your dr to Dr. B's guidelines (and surely ILADS Guidelines).
Also, your having the runs is a big concern. Bring it up with the dr. Are you taking Sacharomyces Boulardii, along with plenty of other high quality probiotics? Those are a must---away from abx.
I hate to say it, but your LLMD sounds not up to snuff. Is it Dr. L in VA by any chance?
Anyone else, as to how you dose rocephin---experiences? Or how you dosed it in the past.
Posts: 3771 | From around | Registered: Mar 2008
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posted
I am seeing a good LLNP that usually follows Burrascano guidelines. I take VSL DS #3, theralac and Saccromyces Boulardii. My gallbaldder got taken out last November.
I have trouble eating most everything because it sits in my stomach or GI tract. I don't know how you can have the runs and not clear out but I seem to do that. The only food that doesn't make me sick is the organic eggs I get from my chickens. However, I can't just eat eggs all the time and I love veggies but can't tolerate most of them.
Plus the rifampin has put my thyroid T3 lower than ever. My integrative doctor is upping my cytomel hoping to compensate. My estrogen and progesterone are nuts too. I am in menopause but need bioidentical hormones. Gosh and this is a flagyl week too. Ugh!!
Doing another blood test Saturday. In the past I saw Dr. J in DC and that was a disaster.
-------------------- Faithful
Just sharing my experience, I am not a doctor. Posts: 2682 | From Colorado | Registered: Oct 2009
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posted
Am I the only one here on just 2 grams rocepin once a day for 5 days a week?????
-------------------- Faithful
Just sharing my experience, I am not a doctor. Posts: 2682 | From Colorado | Registered: Oct 2009
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TF
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Member # 14183
posted
faithful, in April when we discussed this, your doc said she would "poll her colleagues" about the currently used dosage.
So, you could bring up that her poll (if she did it) doesn't seem to match the dosage people are reporting on LymeNet. You could send private messages to the posters on this thread to get their doctors' names. Then, you would have that info to tell your doctor also.
Posts: 9931 | From Maryland | Registered: Dec 2007
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posted
TF-I can do that with the two who posted here. My phone appt is tomorrow and the conversation I had with my practitioner was 60 days ago. She has not gotten back to me on that and has been in Europe at a conference for at least part of that time.
Tomorrow is the first time I will speak to her since April.
I just ordered a rife machine. I am hoping that will help.
-------------------- Faithful
Just sharing my experience, I am not a doctor. Posts: 2682 | From Colorado | Registered: Oct 2009
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sammy
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PM sent for faithful, good luck with your appt tomorrow. I hope that you are able to talk with your doctor tomorrow and get your dose adjusted properly.
Rumi, I took the Rocepin both twice daily and all 4g once daily. You can do it either way you prefer and can tolerate.
One of the Infuserve pharmacists explained it to me in detail. That was a long time ago... Basically what I remember is that we need to keep the blood levels high/saturated. So with the Rocephin it does not matter if we take it once a day or twice a day as long as we take it that day. He compared it to adding more water to an already saturated sponge. We don't have to water it twice a day, one big water is enough.
The pharmacist of course told me in much greater detail. I hope that you can get the general idea.
When I was on Rocehin I had a double lumen PICC line. I used this to my advantage and ran both doses of rocephin at the same time. So you could easily run them back to back if you tolerate them well.
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Rumigirl
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Member # 15091
posted
So, sammy, did you/do you take 4 grams daily for 4 days or for 7 days a week?
faithful, good luck, you need to stick to your guns on this one. I hope that you were taking Actigall before you lost your gallbladder. That is usually given to prevent losing your gallbladder, when on rocephin (although that didn't prevent me losing it).
You also need to talk to your dr about your having the runs and about not being able to digest/tolerate much food. Both are serious issues, of course.
Posts: 3771 | From around | Registered: Mar 2008
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sammy
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Member # 13952
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Sorry, I did not make that clear. I took the 2 gram dose once daily 7 days a week for little while.
Then switched to 2 grams twice daily 4 days a week, 3 days off in a row.
Then I took all 4 grams once daily 4 days a week, with 3 days off.
My doctor recommends the Rocephin 4g total daily dose 4 days a week with 3 days off, if patients can tolerate it.
Posts: 5237 | From here | Registered: Nov 2007
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posted
faithful777- that's what im on 2grams/5 days a week in a row then two days off. along with all the orals
Posts: 229 | From Forty Fort, PA | Registered: Feb 2012
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posted
Just got off my phone appt. We are finishing up the Rocephin at 2 grams twice a day but going to clindamycin IV next. Dr. J has had success with using this medication so my LLNP is putting me on this when the Rocephin is gone.
Changing up the orals too. Stopping the Rifampin and Flagyl for a short time to let the GI tract a break.
Clindamycin is cheaper, so if it works, it is a double boost for me.
-------------------- Faithful
Just sharing my experience, I am not a doctor. Posts: 2682 | From Colorado | Registered: Oct 2009
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