posted
My husband and daughter catch the occasional cold and flu when they seem to be 'going around'. I don't.
I only get a few "bad" days and maybe a sore throat and I think I'm catching it, but it never progresses into the sniffles and coughs, etc., that the rest get.
Either my immune system is awesome or just not working much at all. Which is it?
Posts: 161 | From vancouver island | Registered: Feb 2012
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Razzle
Frequent Contributor (1K+ posts)
Member # 30398
posted
Most symptoms of colds/flu are from the immune response to the bug rather than the bug itself. Therefore, I'd suspect immune suppression to be more likely in the setting of Lyme/coinfections.
-------------------- -Razzle Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs. Posts: 4166 | From WA | Registered: Feb 2011
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
Read the abstractin the link above (scroll down to it)...especially the very last sentence...the last few words.
Th17 cells are implicated in MS.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
The immune system is NOT suppressed in lyme, but is harmed/wounded/damaged and is forced to go in a wrong direction.
The pathway to destroy Bb is the lectin pathway which would totally chop him up into tiny bits and pieces.
And the other pathway called the classic pathway involves our antibodies. Our antibody to Bb's OspB is damaged. And in chronic lyme, OspB reigns.
All that is left is the alternative pathway.
What happens is this...
The classic pathway and the lectin pathway and the alternative pathway all "meet" at C3 - an area to chop up Bb's proteins.
But...the classic and lectin pathway work "upstream" and cleave/chop C1, C2 and C4
BEFORE
getting to C3.
Which means...we don't/can't fully cleave Bb's proteins...which are antigens that we constantly react to.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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lyme in Putnam
Frequent Contributor (1K+ posts)
Member # 11561
posted
I haven't gotten a cold in years.
-------------------- He took u to it, He'll you through Posts: 2837 | From NE. | Registered: Apr 2007
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posted
Thanks for the information, Marnie. Very informative as always!
I must say that an immune system that is harmed/wounded/damaged and forced to go in a wrong direction is an immune system which is quite effectively suppressed!
I'm pretty sure that the reason some of us don't catch colds in the classic sense (sniffles et al), is because our immune systems are either; a) overloaded, b) suppressed, c) watching Friends reruns, or d) All of the above.
Posts: 161 | From vancouver island | Registered: Feb 2012
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