annxyzz
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Dr Lawrence Klapow did a controlled study with Harvard and found a LARGE majority of them infectted with cryptostrongylus pulmoni - a rondworm that is also a lungworm . It can affect multiple organs .
Personally , I question if this is also not a common lyme patient issue , as many of us have breathing , lung , and asthma isssues. If you google " lungworm CFS treatment " you will find patients on other health forums with CFS and lyme who are also reporting testing positive with strongyloides parasite or with the lungworm. Most state they are treated with ivermectin, praziquantel , or albenzadole .
Is this a missing link for those of us here ? I do not know and am not a medical professional. I do have to marvel at the discovery and the fact that thousands of lyme patients have taken multiple rounds ( YEARS ) of ABX , often with little benefit . ABX alone will never eradicate parasites as we know.
I am sharing this because it may spur others here to do their own research . If anyone has anything else to add ,please do .
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sparkle7
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Yes - I don't know why there was only one study about this & everything seemed to "crawl back into the woodwork"... I looked.
The suspicion was that the lungworm came from SE Asia when veterans from the VietNam War came back from the war... Who knows?
In any case - good to do an anti-parasite protocol if you are having trouble getting well.
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annxyzz
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I also found a site that indicated some lyme patients had tested positive for lung worm . If you google "lung worm lyme disease " you may find it .
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sparkle7
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The testing, in general, seems very inadequate. I believe that you have to test the mucus from the lungs to see if there is lungworm present.
So, in many cases - we really don't know what we are fighting. The only way to tell is if something actually works to make us feel better. This is why I don't think long term abx are a good idea. If we keep taking larger & larger doses of something that isn't working in the first place - it can cause alot of damage to the biome.
We need an intact biome to help fight whatever it really is - if it's not actually Lyme or the co-infections. Abx can also cause other problems, too.
I'm not saying people shouldn't take abx - I just think you have to carefully observe whether they are actually working. It's not easy to differentiate between a herx & an adverse side effect.
More & more abx can cause whatever bug it is to encyst, as well - then, you are back at square one when you stop.
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annxyzz
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Sparkle , I think people are being treated with albendazole and ivermectin from what I have read at other health boards . I wish you would post the article about Dr Klapow and lungworm and CFS . Some lyme patients are also testing positive according to other haealth boards I checked .
I do not know how to post the article or I would do it myself .
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annxyzz
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There is an interview I read online with Dr Klapow . He suspected a parasite with lungs because so many CFS people ( like lyme people ) had mycoplasma pneumonia and chlamydia pneumonia. Breathing problems were regularly a part of the disease . ( Sounds familiar to me . Wonder if it may also be a big part of lyme disease . )
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sparkle7
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CFS Radio Program Jan. 16th, 2000. Roger G. Mazlen, M.D. Host with Dr. Larry Klapow.
Dr. Mazlen: Dr. Larry Klapow was a guest on this past Sunday's CFS Radio Show and gave a very important and very informative report of the work he has been doing. Dr. Klapow has been finding a new roundworm type of parasite in CFS patients called "Cryptostrongylus pulmoni".
I found this show to be of particular interest to me because I have been found to have this particular parasitic infection and was very interested to learn of the immunologic dysfunctions that it can cause. I truly think that this important work definitely plays a part in the complex puzzle that is known as Chronic Fatigue Syndrome.
Dr. Mazlen To kick off the new millennium with a good show that you'll find of great interest and great importance, I'm talking today with Dr. Larry Klapow, a Ph.D. in Invertebrate Biology who's in Burlingame, California near San Francisco. Good morning Larry, welcome to our show.
Dr. Klapow Good morning, Roger, I'm glad to be here.
Dr. Mazlen Can you tell our audience something about the this suspected new parasite that you've found in a percentage of patients with Chronic Fatigue Syndrome? How'd you find it?
Dr. Klapow Well, Roger, it came about as a result of a conversation I was having with an immunologist friend of mine, Dr. Vincent Marinkovich, here in Redwood City, California. He was treating a CFS patient we thought might have a roundworm infection. The patient had a low grade eosinophilia and some unusual rashes on the torso that suggested the possibility of threadworm disease.
Antibody tests and stool tests were negative. I thought about this for a while and I know that some chronic parasites migrate between the digestive tract and the respiratory tract and some of them are coughed up in sputum. So I looked at the sputum and that's where I found it. I called the new parasite "Cryptostrongylus pulmoni", that's a provisional name and it means "the hidden lung worm".
Dr. Mazlen That's pretty appropriate in terms of what you say.
Dr. Klapow It definitely is, Roger. It's very difficult to find. And I hope other people will start looking for it. In fact, I've put together some material that I think can help them.
Dr. Mazlen You recently completed a small blinded study in cooperation with a small number of CFS doctors including Dr. Anthony Komaroff in Harvard. You're now doing a larger blinded trial and you're also trying to develop a clinical test for the parasite. But for these other investigators and clinicians, can you tell us what does the parasite look like and how can they find it?
Dr. Klapow You can identify the parasite, the female by its mouth parts and the male by its very intricate reproductive structure. This parasite is very small. The female is less than a millimeter long and the male is about a third that length. So, in addition to being small there's also a lot of difficulties. The specimens I usually pick up are naturally expelled in sputum and they're usually very decayed and rare and because of this you need very specialized imaging techniques to find them.
They're not expensive techniques, they're just specialized. In any case I wanted to help people look for this parasite and so I put together a website which describes how to find it in great detail. It also includes anatomical drawings. I can give you the website address if you like.
Dr. Mazlen Yes, give us the address right now, that'll be great.
Dr. Klapow OK, I'll give you my own email address and then I can post the other rather longer address for people who contact me. My email address is [email protected].
Dr. Mazlen Now, this is really important because this introduces a whole new dimension about Chronic Fatigue Syndrome and its possible relationship to roundworm infestation. Can you tell us so far, at least, as you've been looking, what percentages of Chronic Fatigue Syndrome patients are turning out to be positive for this worm?
Dr. Klapow Yes, I find the parasites in about 40% of three-day sputum samples from CFS patients. However, I have to tell you that yields are very low. In fact, they're so low that I think I'm probably missing as many positive patients as I'm finding. The problem here is that over 80% of the positives I get are represented by only one identifiable specimen. So just by chance it looks like I'm missing a fairly high percentage.
Dr. Mazlen So, the prevalence can be a lot higher and this, of course, stirs some very great interest in terms of causation and etiology which we'll go into later. Can you tell us anything about the blinded trials so far?
Dr. Klapow Yes, I did a small blinded trial in cooperation with a number of doctors including Dr. Anthony Komaroff at Harvard and here are the results. I think they're interesting but you judge for yourself. 5 of the 11 patients were positive while all 6 controls were negative. Now, it's a small trial but if you were trying to do as well by guessing, say by just tossing a coin, you'd only do as well as I report here in about 1 in a 100 tests, so it's a very hard thing to do by just guessing.
The results of this small trial can be used to devise an experimental design for a large trial that could give a statistically significant result and going through that exercise suggests that between 50 and 80 samples will be needed. Now, it may take some time to process these samples microscopically.
It's now taking me somewhere between 50 and 100 hours to find a single positive patient so I think the progress will be slow, that is unless we can get something more rapid going in the form of a PCR test.
Dr. Mazlen Well, I certainly congratulate you though for the effort that you're making because this is totally important to patients for their prognosis and recovery ultimately. There's a lot more to learn and, of course, we're going to go into that and you mentioned the PCR test and that you have some arrangements whereby this can be developed and hopefully you'll get some funding to help this along soon.
If anybody in the audience is interested in helping in this regard they can reach me at [email protected] which is my email address and I'll forward it on to Dr. Klapow. Larry where do you think these parasites might be coming from?
Dr. Klapow Well, Roger, they have some specialized anatomical structures that suggest that they're related to parasites of animals that live in the jungles of Southeast Asia.
In fact, there's been somewhat of a history of hard to diagnose parasites coming out of that area and being brought back to "Western" countries after periods of warfare. It happened in the Victorian era when French soldiers were returning from this area and brought back the chronic parasite Strongyloides stercoralis to Europe where it was first diagnosed in 1894.
It also happened again in World War II. This time British soldiers became infected while they were imprisoned in Burma returned to England and 30 years later, in 1974 they were diagnosed with chronic parasites they had gotten while they were in prison. It's kind of a testament to how difficult some of these parasites are to find and treat. I would like to look at people who've been to Southeast Asia and I think I plan to do that as soon as I finish with the large trial I'm doing on CFS patients now.
Dr. Mazlen It's a natural sequitur because you're going to be having a chance to look at all of the veterans of the Viet Nam era who either served in Viet Nam or Cambodia or neighboring areas.
Dr. Klapow That will happen, I think, rather quickly if I can get the PCR test going.
Dr. Mazlen You say it might be coming from this source and that's a possibility. How is it contracted? How do you get it then?
Dr. Klapow I'm really not sure. What I can tell you is this. I've never seen a fresh transmissible stage of the parasite in any sputum sample I've seen so far. I've done a couple of hundred samples at this point. So I don't think there's any evidence right now of casual transmission.
But roundworm parasites are typically acquired by eating contaminated food, but an outbreak of Cryptostrongylus infection, if it were transmitted in this way, would look very different then a typical food poisoning incident where people get sick within a couple of hours after eating.
Dr. Mazlen That's due to the long latency that you mentioned.
Dr. Klapow Cryptostrongylus is very small but it produces a larvae which is very large so there's an implication here that it must be reproducing very slowly and possibly has a very long latency time. Of course, we know that the outbreak of Chronic Fatigue Syndrome usually take place over several months and in some cases a couple of years and that I think would be consistent with the possibility of a food borne infection with a very long latency period.
Dr. Mazlen Well, now we're going to turn to the clinical side. Most of the time that doctors are looking for parasitosis, they look to see elevated eosinophil and serum IgE, or immunoglobulin E, levels in patients. Isn't this usually the case?
Dr. Klapow Yes, but that's the first question that I get from doctors when I tell them that I found what I think is a new species of roundworm parasite. Where's the elevated IgE? And the answer is elevated IgE is mainly apparent in acute roundworm infections.
With time, the chronic parasites are able to suppress the IgE response and many of them produce a clinical picture where the patients either have normal or lower than the normal average level of IgE and, in fact, that's the picture you see in CFS and in all the studies I've reviewed, IgE is lower in CFS patients than in healthy control populations.
Dr. Mazlen Here I want to interject that I'm part of the new study looking into C.pulmoni in CFS patients and one of the things that prompted me to call you and talk to you about getting involved is the fact that I had been seeing low IgE levels, low eosinophile counts in patients that I thought were inappropriate.
Dr. Klapow In fact, there was a paper that's a few years old in the Journal of Chronic Fatigue Syndrome that indicates that if you correlate IgE and eosinophil levels with the number of symptoms the patients report, the sicker they are the lower the IgE and eosinophil counts and that's a statistically significant relationship.
Dr. Mazlen And I see it and it seems to be borne out. Now, what do you think is suppressing IgE in this CFS or Chronic Fatigue Syndrome patients? What's the mechanism?
Dr. Klapow Well, I think the mechanism may involve the cell marker CD23 which suppresses IgE. There are a couple of other things that activate CD23, the IgE suppresser and those are active herpes viruses and some of the TH1 cytokines, particularly interferon-gamma and the 2'-5'A, the activator of the latent RNase enzyme.
Both herpes viruses and 2'-5'A, as you know, are highly elevated in CFS patients. In fact, it looks like some roundworms may be using chronic viruses as cofactors to help perpetuate their own survival.
Dr. Mazlen That certainly rings true from what I've seen clinically and that leads us to another question. If a lot of Chronic Fatigue Syndrome patients have allergies, they should have elevated IgE levels but a lot of them, as we were just saying, don't. It seems to fit the model you propose of a suppresser.
Dr. Klapow Yes, there are some doctors, in fact, that think allergy is a risk factor for getting a roundworm infection and that's because patients who tend to produce too much IgE to non-specific stimuli, harmless things, may not have enough reserves left over to fight off the parasites so they get a foothold,
and in fact, initially, you can even see patients who report increased allergies, but later on when they're diagnosed with CFS and the presumptive parasite, if we may go so far and speculate, has suppressed their IgE response and the values come out clinically low.
Dr. Mazlen Now, this brings us to a leading question, which, obviously is a speculation, but that's all right because that's what this show is about. We want to raise issues and have other people contribute to answering them as well.
There seem to be many infectious agents that have been proposed as being possible etiological agents for Chronic Fatigue Syndrome. None of them have held up specifically as a single causative agent. What do you think about this roundworm infection, c.pulmoni, is it a primary infection or is it just another opportunistic organism?
Dr. Klapow Well, I don't know if it's a primary cause of CFS. We'll just have to have to go through the rules of Koch's postulates and see how far we can get. I think it's an interesting candidate for a possible primary agent.
I don't think it's an opportunistic infection. Opportunistic infections are usually airborne and are present everywhere. They're just waiting for our immune systems to be weakened before they establish a chronic infection. Cryptostrongylus doesn't seem to be ubiquitous. If I'm right about the taxonomy, it looks like it's coming out of a particular geographic area.
They're are also a number of things that I think can connect roundworm infection to the major physiological systems that malfunction in CFS. And they have to do with the wide variety of physiologically active agents roundworms are able to secrete.
Dr. Mazlen We're going back now and talking about the hormones that these roundworms secrete, namely vasoactive intestinal polypeptide, which is known as VIP, and hippocampal cholinergic neurostimulatory peptide which is known as HCNP, and what they do and Larry, what do these hormones cause? What do they do?
Dr. Klapow Well, VIP is involved in regulating blood pressure and blood flow. It's important in regulating blood flow to the brain. It's believed to be implicated in orthostatic intolerance from which a number of CFS patients suffer.
And, it also controls hypothalmic CRH, a hormone that's ultimately responsible for the level of cortisol in the blood which is suppressed in CFS and it's also suppressed in chronic roundworm infections. And the other one, HCNP, is a limbic system neuropeptide and it's believed to be involved in memory and immune function.
When it goes wrong in areas that have Alzheimer's lesions, there are cognitive symptoms. In fact, some doctors have suggested that CFS looks in some respects like a reversible form of Alzheimer's.
Dr. Mazlen It seems like that sometimes.
Dr. Klapow Well, the bad news is that it bare's any resemblance to that disease. *What good news there is, is that the cognitive symptoms come and go, without apparently doing permanent damage. I think it is a reasonable hope that increasingly effective treatments for CFS will be found in time to substantially help most of those who now suffer from this difficult and often misunderstood disease.
Transcribed by Carolyn Viviani
*Added to transcript by Dr. Klapow after the show.
Source: Transcribed by Carolyn Viviani; [email protected]. (Note: The CFS Radio Show has once again lost its sponsor so this will be the last show until a new sponsor can be found.)
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annxyzz
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Thank you Sparkle VERY MUCH!! This is informative and shows that we need to consider all varieties of pathogens .
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sparkle7
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I've been observing that after taking the Raintree A-P - I've been coughing up small amounts of mucus - sorry about the TMI factor...
It's not really enough to cough out so it gets swallowed. I think this may be part of the lifecycle of the hidden lungworm...? Just an observation... It migrates between the lungs & gut from what I have read.
I know this has a pretty high "yuck" factor but it's something I've been observing.
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sparkle7
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I tried to repost it but there was a problems with the HTML & parentheses...
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annxyzz
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Thank you SPARKLE!!! I do wish there was a test but I agree with his idea of testing for parasites by RESPONSE to ivermectin . That is logical.
I have been on this board about 8 years and read so many posts about people never really getting well with ABX . I took them 3 years with little improvement at all . I did not think parasites were credibly part of this disease and believed it sounded too hokey or far fetched . But after my response to ivermectin and pyrantel , I have to wonder if the reason we do not get well after years of ABX combos is because many of us have parasites! And taking ABX for most parasites is probably as effective as treating a migraine with a VIT C tablet or a slice of bread . ZILCH applicability to pathogen.
In my own experience I had BAD herx with ivermectin (!!!) then slowly started having MORE energy than I had in years .I NEVER had improvement in energy with ABX in 3 years. When I stopped ivermectin all symptoms came back . I can see why KLapow says it is a long term issue and that eradication may be unrealistic . I am going to pursue this avenue because it seems very logical and very little risk is assoc with these meds if rotating and also using herbs. Thanks VERY much Sparkle!!!
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kelmo
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My daughter's illness really started to spiral down when she started with breathing problems. It was diagnosed as mycoplasma at the time, which most doctors just write off as a transient virus.
However, all through her treatment (six years) she has been coughing up green stuff.
I often wonder if it was a bite of a vendor taco in Tiajuana when she was a year old. We had run out of her food, and she was starving. We ate the tacos and did okay.
It could be all kinds of things. But, I developed bad lungs after a serious bout with pneumonia that they never figured out what caused it.
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CD57
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I always have blown off parasites as possible treatment because I have no GI symptoms or pain and haven't traveled to dicey countries. Also my symptoms have always been neurological (tremors, twitches, brain stuff) and heart/tachycardia, and read like laundry list of bart and Lyme symptoms.
Can parasites even cause neurological symptoms that sound like Dr B's list of bart?
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annxyzz
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From all I have read - yes .
-------------------- annxyzz Posts: 1178 | From East Texas | Registered: May 2009
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annxyzz
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It appears that most people who take albenzadole or ivermectin herx miserably . Many of us who take pyrantel pass hundreds of seed or tiny egg looking articles. Several members here are FEELING BETTER ( though most felt worse for a while ) which indicates parasites are not just a problem in third world nations. Logic would say we can not ignore the possibility .
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CD57
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Annyzz -- I know you have been researching this like crazy also. Thanks for responding. Are the Ivermectin herxes also brain ones or just passing stuff? that I can handle.
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annxyzz
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My brain is never great so I can not judge a brain herx . For me the ivermectin was as intense as taking my first doxycyline tablet when I started treating lyme - a sick all over feeling . I still have to take it every other day or I can not function because of intense die off . I never had diarrhea and did not pass weird things at first . But I felt chilled and fluish and sick all over.
After three months ai started feeling better, but stopped because i was not sure how long it was safe to take . I actually had an improvement in energy level. After stopping , I went downhill. ( I never had energy improvement on ABX !) I have restarted and am herxing some again , and I have a hard time with the die off . I believe it contains a bacteria that can make you ill - called wolbachia (?) . I think I am allergic to it . However I am perservering because I do believe parasites are not a hokey far fetched notion . There are others here who are seeing some beneficial results .
One friend has been ill for years severely w lyme/ morgellons. She has been taking fenbendazole and feeling much better and having a more normal life .
If you google: "morgellons lymebusters fenbendazole" you will find many other people on boards treating parasites and sharing they tested positive for ascaris , lung worm , or strongyloides . Some just tested by trying meds and had a big herx and were more inclined to consider parasites as a LYME or CFS problem . I do not mean to overstate the issue , but our theory that parasites are not in the US , a developed nation, is not accurate .
I thin Gael was right , they may well be a part of different common chronic illnesses .
Hope this helps someone .
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lymielauren28
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This is all very good info! Both my husband and I have been dealing with lung/breathing issues for about 8 months now. I've been dealing with Lyme and co's for several years, but this past October we both came down with an acute respiratory "something", and we've yet to get rid of it.
After contracting this "something" we both started on a downward spiral. We've been on abx for several months now as well as antimalarials, and while most of our symptoms are much better - our lung/breathing problems are not.
Symptoms are extreme shortness of breath, chronic cough and coughing up copious amounts of sputum. I know that's gross, sorry. Whatever it is though it's impervious to flagyl, Zithromax, doxycycline, rifampin, minocycline, bactrim, biaxin, malarone and artemisinin.
We've spoken in depth to our LLMD about it and he's as perplexed as we are. He advised us to see a pulmonologist and to have a culture of our sputum to see if anything could be identified. The day before my last appointment I coughed up what honestly looked like a piece of tissue or flesh. It FREAKED me out!! I took a picture of it but not really sure what good that will do me...
I'm going to speak to him at my next appointment about starting ivermectin and see what he says.
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annxyzz
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MORE INFO: If you google "lymebusters ivermectin improvement " or "lymebusters albenzadole improvement " you WILL find a variety of people across US sharing their experience treating parasites and their doctor's particular plan . Pretty interesting !
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nefferdun
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Protoyixzoa is a blood parasite and it causes a dry cough and hoarse voice. Ivermectin has made a huge difference for me. I ran out of stromectel, the human version, and had to use horse wormer which I don't tolerate as well for some reason.
So I cut back and was using it every other day instead of every day. I began to have minor symptoms return like headaches at night, frequent urination and mild pain in one knee.
I don't know how safe ivermectin is. The wormer says it is not for human consumption and do not give it to horses intended for human consumption (horrible thought). I wish I could get more information on safety.
But I feel better than I have in years so it is working.
There are other things I am doing to - the low fat veganish (vegetarian) diet, LDN and methyl cycle supplements. But I can't cut back on the stromectol without symptoms creeping back in so that is important.
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annxyzz
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Ivermectin is used in other countries for long periods , and is generally safe . From what I am reading many start feeling better and then feel worse if they stop. That is my experience also .
From reading other boards I am gathering people find treatment has to be a long time and many rotate drugs and herbs , or pulse the drugs off and on . Many lyme morgellon people post they see improvement , but must continue the treatment to feel better . These have lived and reproduced in us for years and will not die in a short time.
ALL ANIMAL MEDS say : "not for humans "! My phrarmacist says that is bec pharm mfg want you to pay more on human version. If the drug is safe for a human , then the animal version is most likeley the EXACT drug . Do your research , but vet meds are made to strict lab standards and are NOT inferior products . I have used many Thomas Labs products successfully . Also , I have no problem with horse ivermectin and it is cheap ! I plan to continue and take it every other day .
I have afriend who has been improving on fenbendazole aafter no good results with ABX . Fenben has been used primarily for animals . Lots of lyme morgellons people are using iver and fenben from reading other boards . Parasites may have to be treated forever on some sort of basis as Gael has conjectured .
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annxyzz
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Lymie Lauren , You might want to check out posibility of lung flukes , which can be transmitted through fruits and veggies . Google the protocol at : "curezone fluke drug protocol ICU "
It employs albenzadole and praziquantel . I think cats and dogs get these flukes as well as humans . The flukes are in lungs and in gut .
-------------------- annxyzz Posts: 1178 | From East Texas | Registered: May 2009
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Dr Eva Sapi has discovered Onchocerca worms in Lyme ticks in US. Elena
"Recently, Dr. Eva Sapi, Ph.D wrote a fascinating article about the role of parasites in chronic Lyme � similar to the role of biofilm the parasites hide and protect the spirochetes from antibiotics, herbal treatments and our own immune systems.
Dr. Eva Sapi Ph.D. is an Associate Professor of Biology and Environmental Science at the University of New Haven, where she combines teaching with research, leading graduate students in developing a higher level of understanding of Lyme disease. . She has organized three national Lyme disease conferences in the last several years and has taken over much of the research that Dr. Alan MacDonald conducted over the last 30 years regarding the importance of biofilms in eradicating Lyme disease.
In her research, Dr. Sapi also investigates the presence of different formations (spirochete, round bodies and biofilm) of Borrelia burgdorferi, the Lyme disease bacteria which has been highly controversial since it was first released by Dr. Alan MacDonald in Vienna in 1985 when Dr. MacDonald stunned the medical world with a special slide show on neo-natal tissue that he had amassed over years of autopsying stillborn babies as the pathologist at South Hampton Hospital. Using a darkfield microscope technique to capture the images on film, Dr. MacDonald presented his shocking hypothesis to the world at the Second International Symposium on Lyme Disease and Related Disorders. Unfortunately he was ridiculed at the time. As the years have passed, evidence continues to mount validating the tedious and detailed work by Dr. MacDonald and his associates such as Dr. Sapi. When Dr. MacDonald developed Alxheimers, scientists and medical researchers rushed to continue his important work � in many cases directing their research into other areas using his important groundreaking work.
For instance, Dr. Sapi also studies resistance of these different forms of Borrelia burgdorferi to antibiotics and natural agents.It has been proposed that certain parasites could also be a factor in Lyme disease. European doctors have already incorporated Ivermectin, an antihelminth drug, into their Lyme disease protocol with surprising success. Ivermectin is well known for its effectiveness against filarial nematode infections and is often used by veterinarians to eradicate parasitic infections.
Can Lyme disease patients have filarial nematode co-infection and can they acquire this infection from ticks? The only evidence reported of filarial worm presence in ticks was from a study by Burgdorferi� in 1984 where thirty microfilarial worms (species not identified) were found in one adult Ixodis dammini tick in Shelter Island, NY.
Black flies have already been identified as vectors of filarial nematodes. Interestingly, ticks can also be used as an in vitro experimental vector system to study the transmission of filarial nematodes and it was shown that the infected nymphal stage could transmit the filarial worms. If filarial nematodes could be a tick-borne co-infection of Lyme disease patients, their eradication would require additional treatments using specific filaricidal drugs, which could explain why standard antibiotic based protocols often fail in some chronic Lyme disease cases.
Preliminary research data on the potential presence of filarial nematodes in ticks from the University of New Haven research group, suggested that Ixodes tick could harbor filarial nematode DNA sequence and these sequences have high similarity to one of the filarial nematode species called Onchocerca.
Filariasis infects more than one hundred and twenty million men, women, and children throughout the world. There are a number of nematode species that use mosquitoes as their vectors, causing different lymphatic filariasis infections. Onchocerca volvulus, for example, is responsible for river blindness.
However, it is very possible that the species we have found in deer tick is a novel Onchocerca species due to that there are only being partial similar to known Onchocerca species. A phylogenetic approach is being used now to determine the exact filarial genus and species similarity.
Identification of this potential novel tick-borne pathogen could help to design more specific tests and treatment for patients with a tick bite history and could provide a novel therapeutic target for physicians to explore for those chronically ill Lyme disease patients, not to mention the smaller percentage of people who contract Lyme from biting flies, fleas and mosquitoes."
-------------------- Justice will be ours. Posts: 786 | From UK | Registered: Oct 2007
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annxyzz
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Thank you for this article. It is valuable and may explain why multiple rounds of antibiotic combinations never eradicate the sickness assoc w/ lyme .
-------------------- annxyzz Posts: 1178 | From East Texas | Registered: May 2009
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sparkle7
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kelmo- It doesn't make sense to try to figure where these bugs come from. We just don't know. It could be so many things that we would go mad just trying to count them all.
IMHO - just try to treat them as best as you can.
Thanks for the info about the vet meds, annxyzz. I was a bit concerned but my intuition was saying that they were probably the same as the human ones. Maybe they are even better? LOL
I've been just taking the Raintree A-P. It still seems pretty strong to me. I'm achey all over & it's been like that for most of the month. I think it's doing something.
CD57 - I believe that parasites can cause neuro symptoms.
Please read it. The bugs can have all kinds of symbiotic relationships to other bugs, viruses, fungi, etc. They burrow into tissue & can travel freely throughout the body... Sounds like a nightmare, huh.
Posts: 7772 | From Northeast, again... | Registered: Oct 2006
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annxyzz
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Sparkle - great info here . He answers an important question I had . He states some of the CFS patients that tested positive for lungworm ALSO were lyme positive patients . I also read on another thread that some lyme people had tested positive for lungworm ( I think it was cure zone and prohealth ) as well as HOOKWORM and strongyloides . I can see why some people improve on antiparasitical drugs after no improvement with ABX .
The tests are often not reliable , so it is a miracle anyone gets a correct DX. I read a post that one man at another site was told by his doc that there were no parasite issuesin the US . He insisted on a test from metametrix and was positive for HOOKWORM . You have to wonder how many other CFS ers and Lyme people are staying sick because of parasites that docs believe only exist in Kungabooland .
After reading about this lungworm parasite and the FL 1953 protozoa, and seeing people improve with ivermectin or salt C , I am more convinced that the issue is bigger than most imagined .
-------------------- annxyzz Posts: 1178 | From East Texas | Registered: May 2009
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sparkle7
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Yes. I agree! I has a CFS diagnosis many years ago & got well. It wasn't due to any doctor, either.
I can't see how the rest of the world has all these parasites & somehow the Western world doesn't. It's not logical.
There also may be a symbiotic relationship between the parasites & viruses, retroviruses & bacteria (as in a biofilm). According to others - it may be fungus & heavy metals, too. So, we have to think of this stuff as being synergistic & keep chipping away at all of the toxins.
I'm waiting for my modified citrus pectin to arrive.
Posts: 7772 | From Northeast, again... | Registered: Oct 2006
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I believe a falarial worm came out of my nose. I saved it in the freezer. Dr. Sapi is probably correct.
I am wondering if there is a lab that could identify exactly what it is. Do any of you know? I will see my LLMD on Friday and can ask him too.
Posts: 618 | From NC | Registered: Oct 2009
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I am aware of four paediatric Lyme patients who were, to all intents and purposes, cured by the antihelminthic drug Mebendazole. Obviously anything you try should be under the supervision of a Lyme-literate doctor.
I am also aware of a story that one of our most respected and admired LLMDs told a patient in the 1990s that the best treatment for Lyme was the anti-helminthic Ivermectin. He apparently did not explain why. When asked if he could prescribe it, he apparently said he could not. He explained that this was due to 'politics'.
I am not in a position to say for sure whether the story is true or not, but my gut feeling is that it is.
I believe that if is true, this doctor should share his knowledge with the medical and patient community as a whole. 'Politics' should never be allowed to come before lives.
Elena Cook
-------------------- Justice will be ours. Posts: 786 | From UK | Registered: Oct 2007
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annxyzz
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I read a blog called "lyme roller coaster " online that gave the story of a lady (American ) who travelled to South America to visit family . While there she visisited a doctor who gave her ivermectin , which made her IMPROVE . Apparently iver is used in other countries for LYME . I have read it is used for babs in Africa also . This lady takes drops called ivermectina on a maintenance basis . I doubt with many pathogens that reproduce that total eradication is realistic . However, I do believe the lady began improving and having a life . This is an anecdotal story and can be found if you google it . I am not giving advice .
-------------------- annxyzz Posts: 1178 | From East Texas | Registered: May 2009
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