posted
Ok, so I was gonna post a big hairy question on here about what's the difference betw the cyanocobalamin B12 and the Methyl B12 that Dr B highly recommends.
bc, as you well know, a regular Dr Rx has given me the former as most Drs will.
So I did a little Google search and found this article rather quickly.
It seems to be hocking the patches, which don't look all that great to me, but the basic information was helpful.
I was Rx B12 injections last June, my PCP recently switched me to sublinqual. I noticed the subling didn't seem to do anything for me.
I noticed the Burr Guide mentioned a different form of B12. Now I know why.
Just wanted to share.
-------------------- KentuckyWoman tired of medical run-arounds
Two roads diverged in a wood, and I, I took the one less traveled by, And that has made all the difference. ~ ~ Robert Frost Posts: 221 | From Kentucky | Registered: Sep 2012
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posted
Thanks..!! Been taking cyano for about 10 yrs .. finally got a script for the methyl a month ago. Too soon to tell how it's working for me!
My doctor is so sweet .. I think he sold it to me at cost.
oh... guess it wasn't really a script... lol
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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nefferdun
Frequent Contributor (1K+ posts)
Member # 20157
posted
Thanks for posting that. I learned something. I knew I was supposed to take hydroxy B12 which is converted to methy B12 but I did not know what cyanocobalamin was - shocked it has cyanide.
-------------------- old joke: idiopathic means the patient is pathological and the the doctor is an idiot Posts: 4676 | From western Montana | Registered: Apr 2009
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posted
Cyancobalamin has to be converted to methylcobalamin before the body can use it. When you are sick with Lyme, you may not be able to convert one to the other.
I have been told to take methyl only. It has made a difference but it may take a while before you notice it. Infuserve has a good price for a 30 ml bottle.
-------------------- Faithful
Just sharing my experience, I am not a doctor. Posts: 2682 | From Colorado | Registered: Oct 2009
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Tammy N.
Frequent Contributor (1K+ posts)
Member # 26835
posted
nefferdun - why hydroxy instead of methyl? (I've had odd reactions to methyl...not sure why, but wondering if hydroxy would be better for me.)
Posts: 2238 | From East Coast | Registered: Jul 2010
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Razzle
Frequent Contributor (1K+ posts)
Member # 30398
posted
Because for those with CBS mutation, methyl may stimulate methylation too much if we don't have support for the CBS mutation in place first.
-------------------- -Razzle Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs. Posts: 4166 | From WA | Registered: Feb 2011
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lax mom
Frequent Contributor (1K+ posts)
Member # 38743
Tammy N.
Frequent Contributor (1K+ posts)
Member # 26835
posted
Hi Razzle - These last few weeks I don't have regular access to my email from home (until we upgrade our system, hopefully this weekend), otherwise I would have emailed you back. Thanks for the info you sent. I can't wait to re-read.
What is it that supports the CBS mutation?
Posts: 2238 | From East Coast | Registered: Jul 2010
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posted
I take 1 - 2,5 mg mythylcobalamin every day, but so far it doesnt make a difference.
Posts: 214 | From Home | Registered: Apr 2011
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Razzle
Frequent Contributor (1K+ posts)
Member # 30398
posted
CBS mutation support includes all of the following:
Low protein diet (preferably vegetarian/vegan)
Low sulfur/low sulfite diet
Avoid taurine, cysteine, methionine in supplements and foods (hence the low protein vegetarian/vegan diet)
Limit Vitamin B6/P5P
Yucca sprinkled on protein foods
Molybdenum
Zinc
Magnesium
Iron (if deficient)
Vitamin B12 - hydroxo-B12 form is most useful initially
Ammonia detox flushes = magnesium + charcoal
Kidney & liver support herbs (Dandelion, Parsley, Nettles, etc.)
Deal with metals, if applicable (chelators & binders; but be careful because most chelators contain sulfur and may not be tolerated well)
Dr. Yasko also has some specific RNA supplements, but these are controversial and not all practitioners use them. I can't get an answer out of the manufacturer as to what all is in them, hence I don't take them either.
-------------------- -Razzle Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs. Posts: 4166 | From WA | Registered: Feb 2011
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posted
Anybody know if there is a difference in the Methyl B12 oral vs injection?
Or is it even available in both forms? I just don't know.
I knew about the conversion process from Cyano to Methyl in the body and wondered w a compromised body if that might be the key. Sounds like it.
Now I've never heard of the hydroxy B12.
I would have to venture to guess that which ever one is the "more natural" one would most likely be the better one for the system. Just following the rule of nature that is.
Thanks for all the great input !! KW
-------------------- KentuckyWoman tired of medical run-arounds
Two roads diverged in a wood, and I, I took the one less traveled by, And that has made all the difference. ~ ~ Robert Frost Posts: 221 | From Kentucky | Registered: Sep 2012
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I'm waiting for my PCP to call so I can discuss this option with her. I'm hopeful I can give this method a try.
-------------------- KentuckyWoman tired of medical run-arounds
Two roads diverged in a wood, and I, I took the one less traveled by, And that has made all the difference. ~ ~ Robert Frost Posts: 221 | From Kentucky | Registered: Sep 2012
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posted
Taking methylcobalamin is not a quick fix. It takes time to work. And, the changes can be small and steady.
My husband and I take it daily and after doing this for 6 months or so, we notice when we miss taking our injection. We are both positive for MTHFR with one allele.
Infuserve will do B12 compounding and so would quite a few pharmacies in VA who mail out to people. You just have to call around, but Infuserve is great with pricing.
-------------------- Faithful
Just sharing my experience, I am not a doctor. Posts: 2682 | From Colorado | Registered: Oct 2009
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posted
Dr Burrascano recommends daily injection for 3-6 mos, but I don't think I could do daily shots either.
I am on Cyano B12 injections 1/wk. My PCP added sublingual, but I can't tell they do anything.
I'm just going to see if she will switch it to Methyl B12 injections and see what happens.
-------------------- KentuckyWoman tired of medical run-arounds
Two roads diverged in a wood, and I, I took the one less traveled by, And that has made all the difference. ~ ~ Robert Frost Posts: 221 | From Kentucky | Registered: Sep 2012
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posted
It certainly helped with the brain fog for me. You just have to get into a routine just like you do with all your other medications.
I do the shot after my shower every evening. A 30 ml bottle really lasts a long time if you are doing 2 ml or 2.5 ml. We did .5 ml of a 20 mg per ml bottle until recently dropped to .3 ml a day.
Oral B12 or sublingual just did not help us at all.
-------------------- Faithful
Just sharing my experience, I am not a doctor. Posts: 2682 | From Colorado | Registered: Oct 2009
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