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» LymeNet Flash » Questions and Discussion » Medical Questions » Please help! Question re: possible adverse reaction to Sporanox (Itraconazole)

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Author Topic: Please help! Question re: possible adverse reaction to Sporanox (Itraconazole)
axseptants
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Member # 32296

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All - I posted a similar question a few days ago, but I'm hoping to get a few more responses. I was on sporanox 200 mg. BID for 15 days. I now understand that this is a super high dose. It was prescribed by my OB/Gyn along with diflucan for yeast, which I have suffered with for years. I was not on ABX during the two weeks on the sporanox. He had me do Diflucan once a day for 7 days then one pill once a week for four weeks. Long story short. I take my last dose of diflucant today. I have been off the sporanox for a couple of weeks, but I am still feeling an increase in tingling, numbness, paresthesia, twitching, etc. I felt this withe the first dose of sporanox, but I didn't think much of it. I already have peripheral neuropathy and have for years. What scares me is that the significant increase in tingling, numbenss, twitching, peripheral neuropathy, etc. has not gone away after being off the drug so long. I feel as though low level electricity is pulsing throughout my entire body. I did start back on pulse dose ABX (mino, zith, and Omnicef) this week along with Nattozyme, but I don't think that has anything to do with my symptoms since they pre-dated re-starting the ABX. Can someone please help?? I am scared that this is permanent. I have made an appt with my neurologist, but I can't get into see him until 12/26. I also left messages last week for the nurse at my LLMD's office and my OB/Gyn's office with no word back.

I am grateful in advance for responses. Thank you.

Posts: 52 | From Central VA | Registered: Jun 2011  |  IP: Logged | Report this post to a Moderator
cozynana
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Sometimes I think the drugs stir up the Lyme in our body.

It makes the symptoms worse as we treat them

I took Sporanox too and it seemed to attack my stomach.

Now I have what I think are ulcers from taking it.

If I don't keep something in my stomach I get burning pain that does not let up until I drink a lot of water or eat.

Could you possibly be taking too many drugs at a time.

I seem to do much worse on combinations of drugs.

Posts: 620 | From Ks | Registered: Oct 2011  |  IP: Logged | Report this post to a Moderator
glm1111
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The symptoms you describe sound like you could have a parasitic infection and the sporonax may have stirred things up.

Parasites/worms can be a MAJOR co-infection of Lyme and often overlooked. Google parasite symptoms and check the symptom list at Humaworm.

Gael

--------------------
PARASITES/WORMS ARE NOW
RECOGNIZED AS THE NUMBER 1 CO-INFECTION IN LYME DISEASE BY ILADS*

Posts: 6418 | From philadelphia pa | Registered: Jul 2008  |  IP: Logged | Report this post to a Moderator
glm1111
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[Breaking this up for easier reading

QUOTE]Originally posted by axseptants:
All - I posted a similar question a few days ago, but I'm hoping to get a few more responses.

I was on sporanox 200 mg. BID for 15 days. I now understand that this is a super high dose. It was prescribed by my OB/Gyn along with diflucan for yeast, which I have suffered with for years.

I was not on ABX during the two weeks on the sporanox. He had me do Diflucan once a day for 7 days then one pill once a week for four weeks. Long story short.

I take my last dose of diflucant today. I have been off the sporanox for a couple of weeks, but I am still feeling an increase in tingling, numbness, paresthesia, twitching, etc.

I felt this withe the first dose of sporanox, but I didn't think much of it. I already have peripheral neuropathy and have for years.

What scares me is that the significant increase in tingling, numbenss, twitching, peripheral neuropathy, etc. has not gone away after being off the drug so long.


I feel as though low level electricity is pulsing throughout my entire body. I did start back on pulse dose ABX (mino, zith, and Omnicef) this week along with Nattozyme, but I don't think that has anything to do with my symptoms since they pre-dated re-starting the ABX.

Can someone please help?? I am scared that this is permanent. I have made an appt with my neurologist, but I can't get into see him until 12/26.

I also left messages last week for the nurse at my LLMD's office and my OB/Gyn's office with no word back.

I am grateful in advance for responses. Thank you.
[/QUOTE]

--------------------
PARASITES/WORMS ARE NOW
RECOGNIZED AS THE NUMBER 1 CO-INFECTION IN LYME DISEASE BY ILADS*

Posts: 6418 | From philadelphia pa | Registered: Jul 2008  |  IP: Logged | Report this post to a Moderator
GiGi
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Undoubtedly the worst reaction follows the killing of some fungi/mold/candida. I don't think anything feels as bad.

Fungi/mucor, etc. always involve toxic metals, because our body grows fungi to protect itself from the toxic metals. And parasites are most the time involved and from my experience not just a few. Read my Babuschka Principle post. I have linked it many times, and Dr. K.'s publication of 2004 "Lyme, A Look Beyond Antibiotics"spells out clearly why he treats parasites first. It makes it easier for everyone.

That is why Dr. K. treats parasites first along with the metals and watching out for the fungi. Parasites, toxic metals and chemicals, fungi usually follow in lockstep and it makes treatment of the bacterial and viral infections much quicker and simpler.

Take care.

Posts: 9834 | From Washington State | Registered: Oct 2000  |  IP: Logged | Report this post to a Moderator
Tammy N.
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axs - I posted on your other thread. I think it's parasite related. And like Gigi has posted countless times, as parasites die they release all of the junk they have been holding (viruses, fungi, toxic metals, etc.) All of which can make you feel like hell.

The tingling, buzzing, vibrations were my worst symptom by far.

I hope you feel better soon.

Posts: 2238 | From East Coast | Registered: Jul 2010  |  IP: Logged | Report this post to a Moderator
   

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