posted
Does anyone know if there is a link between MTHFR and lyme disease?
Does having this mutation make you more susceptible to lyme?
Does it make it more difficult to treat?
If you do not have MTHFR, are you less likely to have lyme?
Any info or links to research would be greatly appreciated.
Thanks!
Posts: 91 | From USA | Registered: Apr 2014
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dbpei
Frequent Contributor (1K+ posts)
Member # 33574
posted
My previous LLNP told me that 80% of people who have lyme disease test positive for this genetic mutation. If this is true, it certainly indicates the need for lots more research in this area.
I have the mutation. I have found the following sites helpful.
Razzle
Frequent Contributor (1K+ posts)
Member # 30398
posted
Lyme is known to shut or slow down methylation...
Toxins from Lyme die off can overwhelm the body's ability to produce enough glutathione.
Lyme also produces a fair amount of ammonia, which can use up our BH4 (needed for part of the methylation cycle).
I personally believe everyone with Lyme needs basic methylation support, but that's a personal bias...I have a number of methylation cycle genomic variants, and it is a huge deal for me.
posted
The 23andme.com saliva spit genetic test can show you which genetic polymorphisms you have - ie genetic difficulty with specific enzymes.
We can send the results to geneticgenie for explanation, and then on to a doctor who understands how to support the poorly functioning methylation pathways.
This way you can get specifics of what your body's like genetically.
Posts: 13117 | From San Francisco | Registered: May 2006
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posted
I actually have already been tested and I do not have MTHFR, but everyone else in my family does have the single gene mutation.
Several of them also have lyme disease. I do not have any symptoms of lyme, so I have not been tested because it is so expensive and insurance won't cover it.
That is why I am so interested in knowing if there is a connection between the two.
Posts: 91 | From USA | Registered: Apr 2014
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GretaM
Frequent Contributor (1K+ posts)
Member # 40917
posted
My brother, who does not have lyme, has more mutations than me.
All the mthfr and mthrr plus pretty much hetero of all the others.
When I put his through genetic genie it was all yellows and reds.
Mine still had some green.
Posts: 4358 | From British Columbia, Canada | Registered: Jun 2013
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