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» LymeNet Flash » Questions and Discussion » Medical Questions » List of mitochondria nutrients

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Author Topic: List of mitochondria nutrients
Marnie
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A Pharm. company is developing a combination of low dose Ritalin AND mitochondrial nutrients

to treat chronic fatigue.

The link below (table 2) lists the nutrients and the dosages.

(This is the first link I've ever seen that specifically spells out what nutrients are needed in what amts. by our cells' powerhouses.)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565289/

The "Ritalin" component =

"Amphetamine activates Rho GTPase signaling to mediate ***dopamine transporter internalization*** and acute behavioral effects of amphetamine"

Re: dopamine transporter internalization...hummmm or should I say buzzzzzzzzzz therapy?

http://www.ncbi.nlm.nih.gov/pubmed/22683840

Curious!

Posts: 9426 | From Sunshine State | Registered: Mar 2001  |  IP: Logged | Report this post to a Moderator
Keebler
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Well, we really need to know all this - so thanks for posting it.

We need to know because - once again - they are not looking for the real answers but expensive band aid drugs.

But Amphetamine can destroy an already blasted adrenal dysfunction. Buzzzzzes don't work well for those who have HPA-axis impairment (as most with lyme are hit with as well as those with "CFS" their target audience).

Buzz rather than treat the reason the mitochondria are clobbered in the first place? Infections damage - and also many Rx clobber mitochondria. Address the causes.

My next thought, though, is that food supplies nutrients. Food.
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Keebler
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I highly recommend Terry Wahls, MD book and suggestions for cellular repair.

Although - the * by "recovers" to note she also took minocycline during her process the nutrition discussion in her book is vital.

http://flash.lymenet.org/scripts/ultimatebb.cgi/topic/1/113095?#000000

Topic: Doctor with MS recovers*: shares nutrients & pivotal diet

Focus: "Minding My Mitochondria" by Terry Wahls, MD

"TED Talks" Video and book links.

MYELIN SHEATH & MITOCHONDRIA SUPPORT discussed.


Carol in PA posted elsewhere:

. . . article has a link to an article about repairing mitochondrial function with NT Factor. This helps fatigue.

http://www.prohealth.com/library/showArticle.cfm?libid=15150

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

- by Karen Lee Richards, August 6, 2010
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Keebler
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As for attention span, energy issues, amphetamines pose a risk. Instead, a safer way to address that, in addition to infection attention:

http://flash.lymenet.org/ubb/ultimatebb.php/topic/1/89790

Topic: NATURAL SLEEP & ADRENAL SUPPORT
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Carol in PA
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quote:
Originally posted by Marnie:
The link below (table 2) lists the nutrients and the dosages.

(This is the first link I've ever seen that specifically spells out what nutrients are needed in what amts. by our cells' powerhouses.)


Here is table 2, which lists micronutrients.
Note: there are two columns.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565289/table/tbl02/

Daily dose of magnesium at 200 mg is low.
Iron at 18 mg is too high for post-menopausal women.


Marnie, I don't know if those are actually the right amounts of the right nutrients needed by the mitochondria.
The study states:
"Rather than utilizing a high dosage of a single antioxidant nutrient (e.g. vitamin C, vitamin E, acetyl-L-carnitine, or coenzyme Q-10), a broad-spectrum supplement approach was used in this investigation."

But they don't even use coenzyme Q-10!
And they should be evaluating CoQ10's newest update, MitoQ, because it is so much more effective.


They are trying to get everything but the kitchen sink into one pill.
Trouble is, we need the kitchen sink too, haha.


Editing to add,
By putting a prescription med (Ritalin) into this mixture, they can patent it and make a profit.

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Marnie
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They make a profit with Axona = medicinal food for AD...active ingredient is caprylic acid (in VCO - medium chain fatty acid - saturated = loaded with hydrogen, i.e., "hydrogenated").

Solgar makes "Maximised Caprylic Acid".

We need hydrogen and we need it carried into the cells where...

The mitochondrion itself functions to produce an electrical chemical gradient—somewhat like a battery

by accumulating hydrogen ions in the space between the inner and outer membrane

http://webcache.googleusercontent.com/search?q=cache:5AzRNI_cHPMJ:https://www.trueorigin.org/atp.php


Mito Q is a more bioavailable form of Co Q10 which becomes the antioxidant called ubiquinOL- for those who are wondering. Yes, it helps, but in our mitochondria

to make FMN and FAD in our mitochondria, we need riboflavin, B2...

Once upon a time...

"In the warm seas of the ancient earth, the first living things would have been prokaryotes. The endosymbiotic hypothesis for the origin of mitochondria (and chloroplasts)

***suggests that mitochondria are descended from specialized bacteria***

(probably purple nonsulfur bacteria) that somehow survived endocytosis by another species of prokaryote or some other cell type,

and became incorporated into the cytoplasm."

http://tinyurl.com/b7ym8


I am NOT promoting Ritalin or bee venom therapy, I'm just looking at what they do and see if I can figure out something "safer" that does the same.

"Amphetamine activates Rho GTPase signaling"

Is Rho GTPase = *Rhodopsin* GTPase?

A light receptor to the rescue?

" Light suppresses dopamine responses by upregulating inhibitory dopamine receptors."

http://tinyurl.com/hflufb6

Could Bb do the same as these? Just wondering!

"However, it was found that

either dopamine or noradrenaline

enabled staphylococci damaged by either antibiotic to recover to active growth in less than a day, even bacteria that appeared to have been killed by the antimicrobial.

Clinical levels of dopamine and noradrenaline also facilitated the recovery of P. aeruginosa from tobramycin antibiotic challenge."

http://webcache.googleusercontent.com/search?q=cache:-0PYehu5EfUJ:http://www.hindawi.com/journals/scientifica/2013/361073/

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