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» LymeNet Flash » Questions and Discussion » Medical Questions » Need help reading igenex results !!!!!

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Author Topic: Need help reading igenex results !!!!!
Semia
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Igenex IGM results

**23-25 kda IND
18 kda -
28 kda -
30 kda -
**34 kda -
**39 kda -
45 kda -
**31 kda +
41 kda IND
58 kda +
66 kda -
**83-93 kda -

Igenex IGG results

18 kda -
**23-25 kda -
28 kda -
30 kda -
**31 kda -
**34 kda -
**39 kda -
**41 kda +
45 kda -
58 kda -
66 kda -
83-93 kda -

Anyone know what to make of this??
For IGG it does say that presence of only one double starred band may indicate clinical significance. and 41 is double starred.

But at the top of these pages it says I am negative for Lyme.
Could this just be one of the 27 reasons we get false negatives ??? Any help is greatly appreciated.

Posts: 123 | From New jersey | Registered: Oct 2015  |  IP: Logged | Report this post to a Moderator
TF
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So, you have a + (positive) on band 31 and a + on band 41 and a mild positive on band 23 (Indefinite (IND) is the same as a slight positive). A lyme specialist would say that is enough to treat for lyme.

Here is what Burrascano says:

"Western blots are reported by showing which bands are reactive. 41KD bands appear the earliest but can cross react with other spirochetes. The 18KD, 23-25KD (Osp C), 31KD (Osp A), 34KD (Osp B), 37KD, 39KD, 83KD and the 93KD bands are the species-specific ones, but appear later or may not appear at all. You should see at least the 41KD and one of the specific bands." (page 7)

And, here is what another lyme doc says (Doctor C.):

"In my clinical experience, if a patient has symptoms suspicious for borreliosis, and has one or more of the following bands, there is a very high probability the patient has borreliosis.

These bands are 18, 22, 23-25, 28, 30, 31, 34, 37, 39, 41, 83, and 93.

[---- from DR C's update from 2005 ---
----The significant antibodies, in my opinion, are the 18, 23-25, 28, 30, 31, 34, 39, 58, 66 and 93.----]

This is true regardless of whether it is IgG or IgM."

http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=1;t=042077;p=0

You do not meet the CDC criteria for lyme and you also do not meet the Igenex criteria for saying you are positive for lyme. That is why it says on your test result that you are negative for lyme. This is not the same as a false negative.

A false negative would be no positive results on the double starred bands at all, but yet the person has lyme.

Your test results show evidence of lyme. However, a doctor who is not a lyme specialist would just go by the word "negative" and tell you that you are negative for lyme. Unfortunately, he would be incorrect.

Try to read through Dr. C's entire explanation of the Western Blot so that you understand the significance of your results. They are significant. A good lyme doctor would understand that you must have lyme to have these results. Band 31 is especially significant.

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Semia
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Thank you for your help. I see my LLMD tuesday so hopefully she goes by what you said. Thank you so so much.
Posts: 123 | From New jersey | Registered: Oct 2015  |  IP: Logged | Report this post to a Moderator
Keebler
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-
Glad to see TF's excellent reply. If that doctor is a true LLMD and is ILADS minded, they will assess you in person, and consider that band #31 for certain.
-

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Semia
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Thank you ! Also next to henselae IgG it says 80.
The form says that anything > or = 40 suggests active infection.

So this means im positive for bartonella right ?

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Lymetoo
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quote:
Originally posted by Semia:
Thank you ! Also next to henselae IgG it says 80.
The form says that anything > or = 40 suggests active infection.

So this means im positive for bartonella right ?

-
Sounds like it.

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 95826 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
   

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