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» LymeNet Flash » Questions and Discussion » Medical Questions » Meningiomas/Lyme/lupus

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Author Topic: Meningiomas/Lyme/lupus
me
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Hi! Does anyone have any info regarding connections between meningiomas, Lyme and lupus?

Thank you.

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Tincup
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In this study a Lyme diagnosis was discarded (even with many symptoms and positive history) due to negative Lyme test. As we all know the Lyme tests are terribly faulty, so could the two be related??? Note the date of the report.


Przegl Lek. 1999;56(10):682-3.

[The coexistence of an intracranial tumor and a positive epidemiologic history of Lyme borreliosis as the reason for diagnostic problems--case report].
[Article in Polish]

Biesiada G1, Kalinowska-Nowak A.
Author information

1Katedry i Kliniki Chorób Zakaźnych Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.

Abstract

The authors present the case of a patient treated in the Department of Infectious Diseases at CMUJ in Cracow.

The patient's full clinical picture suggested the possibility of the development of neuroborreliosis and disguised the symptoms of a developing intracranial tumor.

Neuroborreliosis was suspected due to epidemiologic history (a tick bite, erythema migrans), general symptoms (fatigue, hypersomnia, apathy, dysmnesia, concentration disorders) and neurological symptoms, seropositive tests for Borrelia burgdorferi in serum and cerebrospinal fluid (IgG), increased protein concentration in cerebrospinal fluid.

Owing to the fact that the serologic criteria of neuroborreliosis were not fulfilled, and other symptoms (loss of consciousness) appeared, CT was done.

The CT showed the presence of a tumor in the longitudinal fissure of the brain, which, after intraoperative and histopathological examination, was defined as meningioma.
PMID: 10695387 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/10695387

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Tincup
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One of the worst places to have Lyme and go to. Also note the date of the report and the arrogance dripping off the authors- as if they know everything. Fat chance!


J Neuroophthalmol. 1997 Jun;17(2):108-21.
Neuro-ophthalmic manifestations of Lyme disease.
Balcer LJ1, Winterkorn JM, Galetta SL.

Author information

1Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, USA.

Abstract

Lyme disease is a multisystem disorder caused by infection with the Borrelia burgdorferi spirochete. The diagnosis of Lyme disease usually is based on several clinical criteria, with supportive data from laboratory testing.

The presence of the bullseye skin lesion, erythema migrans, is the single pathognomonic criterion. In the 20 years since the initial description of Lyme disease in the United States, B. burgdorferi has been implicated as an etiologic agent in numerous ophthalmic and neuro-ophthalmic syndromes, involving most structures from the cornea to the cranial nerves.

Neuro-ophthalmic and ocular manifestations of Lyme disease include meningitis with papilledema, cranial neuropathies, follicular conjunctivitis, nummular keratitis, and intraocular inflammation.

Although an association with Lyme disease has been purported for numerous other syndromes, a definite causal relationship has not been proved in many cases. During a period of rapidly increasing awareness of Lyme disease, a high index of suspicion and poorly defined criteria for its presence have resulted in over-diagnosis of Lyme disease.

In the authors' experience, the incorrect diagnosis of Lyme disease initially has been made in patients with allergic conjunctivitis, keratoconus, morning glory syndrome, craniopharyngioma, meningioma, CNS lymphoma, paraneoplastic syndrome, multiple sclerosis, sarcoid, syphilis, and functional illness.

Nevertheless, this treatable infection must be an important consideration in the differential diagnosis of certain ocular or neurologic diseases.
PMID: 9176782 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/9176782

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Tincup
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Inflammation can cause cells to go berserk, forming tumors, cysts, cancer, and other abnormalities. Lyme causes inflammation. Here are some cancer/doxy studies that may be of interest.

https://sites.google.com/site/marylandlyme/lyme/cancer-doxycycline-studies

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me
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Thanks so much, TIncup!!!I will pass this info along.
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Tincup
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Referring you to someone who may be able to assist.

[group hug]

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