Jordana
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?
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Keebler
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- Not at all sure what the "tox1" is all about. Still, Yes. Absolutely. Borrelia is extremely toxic - and not just to nerves, IMO.
It can be toxic / destructive to any body organ, function or tissue, from what I gather by articles below and experience. It may not affect each person the same way, of course.
The thing is that many who (who generally discount lyme in general) and "look for it" claim they can't find it because they do not understand the very nature of how borellia works or the ways it can do its damage. For a start:
Biochemistry of Lyme Disease: Borrelia burgdorferi Spirochete/Cyst
by Prof. Robert W. Bradford and Henry W. Allen
Townsend Letter - February / March 2006
Excerpt:
Lyme Disease Toxin
Because many of the symptoms of Lyme disease involve the nervous system, it was speculated that the spirochete produced a toxin that disrupted normal nerve function.
Through the use of DNA manipulations and a database of known protein toxin DNA sequences, a match was made with a selected Borrelia burgdorferi (Bb) gene and a specific toxin in the database.
Protein generated from this cloned Bb gene was examined biochemically and found to have characteristics similar to that of botulinum, the toxin of Clostridium botulinum, a zinc endoproteinase.1
The toxin from Bb belongs to a family of toxic proteins known as "zinc endoproteinases" or metalloproteases, and includes the toxin from the organism causing tetanus as well as those from many other well-known infectious diseases. . . .
The Biology of Lyme Disease: An Expert's Perspective
26 minute YouTube video
Published on Jul 20, 2013
This is a 30 minute video with Dr. Alan MacDonald, a retired M.D. and board certified in Anatomic Pathology and Clinical Pathology. This revealing interview from May 2013 (1 of 3) covers many of the controversies associated with Lyme disease: . . . .
[Dr. MacDonald has many more recent articles / videos so be sure to look those up, too.]
When to Suspect Lyme – by John D. Bleiweiss, M.D. -
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Jordana
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Okay, so it's absolutely been proven that there is a botulism-like neurotoxin that's shed by borrelia?
I'm thrown off by my fave Scary Lady Sarah Vaughter who has insisted there is no proof it exists.
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Is that the neurotoxin that causes "tick paralysis?"
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Keebler
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- Vaughtner is not lyme literate. Her site, alone, is toxic to learning the truth about lyme.
The links in the post above are a good place to learn about the science of lyme.
Also keep in mind that toxicity can be a result of various processes, not necessarily one ingredient. -
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Jordana
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I'm interested in this specifically because I have antibodies for Myasthenia Gravis, which attacks the neuromuscular junction. BBtox1, this toxin, is supposed to block the neuromuscular junction the same way botulism does.
So if it does exist, that gives me another thing to think about while I'm pondering ingesting my covertly-acquired Mestinon.
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Jordana
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p.s keebler, she's over there telling ALS patients how much doxycycline to take...
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Keebler
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- Vaughtner's site is not the place to find truth regaring lyme.
Do you have an ILADS educated LLMD? If so, they would be the person to ask.
Antibodies can "misrepresent" themselves often with lyme, too. Still, a well educated, experienced and successful LLMD or LL ND would be best to consult in this matter.
As well, there are various things we can do to help decrease toxicity in the body. Nutritive liver / kidney support is the base for that. Milk Thistle good to have on board while you sort out the answers. -
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Jordana
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Just bought some and started taking it yesterday on your suggestion.
Yes, I do have an LLMD. I was a little ambivalent about him at first but then I saw he'd actually published on pubmed and felt better.
He said Mestinon was most likely safe to take. The BBTOx angle is just another connection; really I'm thinking about taking it so I can hold my head up without blowing another cervical disc.
Posts: 2057 | From Florida | Registered: Feb 2015
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Keebler
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- One article at PubMed does make an expert. I don't know who your doctor is so its hard to know. Be sure to talk with your local and state - and your neighboring states lyme support groups for reviews on the doctor you see.
And also on the national level, hopefully you've gotten some feedback here. Also post in the LymeDisease.org patient online support to be sure you have the best doctor available to you.
You might also ask him to talk to other LLMDs as to they have had experience with that drug - or other patients with MG issues.
If your doctor is a member of ILADS, there should be an easy way for them to pose that question to others for their input.
It's very important to address the infections, with key support, I think, before chasing any "autoimmune" issue, though. There have been many "autoimmune" issues that have gotten better or even totally resolved when lyme / tick borne / chronic stealth infection are adequately addressed. -
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Jordana
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Thanks, Keebler, I'm on abx. He was actually suggested to me through the Find an ILADS doc service and also the local Lyme support chapter.
He is not very aggressive but he's as knowledgeable I think as most of the docs I've seen online or read about.
I want to try the Mestinon but it still might not work out. It's supposed to stop the breakdown of acetylcholine -- if that means twitching, shaking and trembling( which it does sometimes) so much for that. Low and slow.
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