posted
Hello, my doctor is considering treating me with gentamicin for batonella as I have failed all other antibiotic combinations. Gentamicin is one of the only antibiotics which is bactericidal to bartonella while all others seem to be bacteriostatic based on literature. It does have potentially serious side effects, however I am really considering it based on my horrible disabling symptoms which are keeping me out of work and home bound. Has anyone else been treated with this drug for bartonella?
My doctor is very experienced and careful. He worked primarily with HIV patients throughout his entire career and has used the drug over 100 times. He has only had 1 patient with serious side effects who had HIV.
Posts: 70 | From New Jersey | Registered: Aug 2013
| IP: Logged |
bluelyme
Frequent Contributor (1K+ posts)
Member # 47170
posted
Risk vs benifit. .?.mathias who posted here did 3 yrs floroquinalones and resolved his Als like symptoms. Which is thought to be bart /myco .a few questions. ..what have you tried previously?
is your body able to handle the med? What is your quality of life now ?.what are the side effects? serious problems call for serious measures..i am very curious if this works please keep us posted.
-------------------- Blue Posts: 1539 | From southwest | Registered: Dec 2015
| IP: Logged |
posted
bluelyme. I have been on combinations of zithormycin, minocycline, bactrim ds or rifampin, clarithromycin, doxy combinations for 1 year. I have had mild period of improvement, but often debilitating herx reaction and set backs. My quality of life is extremely poor and do not have a life worth living. If it were not for the strong belief and conviction that I can and will get better somehow I would choose not to live.
I think I can handle the med, but do admit I am nervous. Luckily if I have a really strong herx and heart issues like I have before the hospital is right down the street from me.
Posts: 70 | From New Jersey | Registered: Aug 2013
| IP: Logged |
TNT
Frequent Contributor (1K+ posts)
Member # 42349
posted
I would say go for it. If you know without a shadow of doubt with lab-verified results that Bartonella is what is keeping you ill, then definitely go for it.
Gentamycin and Streptomycin are both in the same abx family, and Streptomycin has been used for decades (when necessary) for other infections, even with children.
I know first hand that THE BART GURU would like to use Gent. and may be doing it by now. I've heard him discuss liposomal Gent. before (IV Gent. is supposedly safer liposomally).
If your doc is experienced, it sounds like a safe calculated risk.
Posts: 1308 | From Eastern USA | Registered: Oct 2013
| IP: Logged |
Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- Gentamicin is very ototoxic. Make sure he's got a solid plan for how to protect your hearing. NAC and some of the herbs used for Liver support is a start yet whatever hearing & vestibular system protection plan would include but also go beyond liver support. -
Posts: 48021 | From Tree House | Registered: Jul 2007
| IP: Logged |
Keebler
Honored Contributor (25K+ posts)
Member # 12673
RIFE Machine - Reference LINKS -
Posts: 48021 | From Tree House | Registered: Jul 2007
| IP: Logged |
Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- Regarding ototoxicity: Neil G. Bauman & Timothy Hain, MD are the experts in this field. Each has a very different background, though, and different place in patient education.
Be sure to get Bauman's most recent book, at the end of this thread. Then back up to see relevant posts. Then, you'll have to search to see what's new since this collection was posted.
Sorry it's not more compact yet, some good detail here and ways to help you learn how to research this aspect of it all.
HEARING PROTECTION is also by what you avoid, sound wise.
LIVER & KIDNEY SUPPORT & and several HERXHEIMER support links, too.
Support for hearing and vestibular system included (yet that would also require more searching for the best plan with your LL doctor). -
[ 04-08-2016, 12:12 AM: Message edited by: Keebler ]
Posts: 48021 | From Tree House | Registered: Jul 2007
| IP: Logged |
Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- The work / books / website for Harrod Buhner, too. He is a master herbalist who is exceptionally lyme literate and studied in the area of tick borne and chronic stealth infections.
He has written much about bartonella as part of his larger works. -
Posts: 48021 | From Tree House | Registered: Jul 2007
| IP: Logged |
Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- I could not get the URL to post. Still, this is such a good article that I hope you'll go to his website and find it:
Gentamicin Ototoxicity
Timothy C. Hain, MD Page last modified: December 6, 2015 -
Posts: 48021 | From Tree House | Registered: Jul 2007
| IP: Logged |
TNT - who is the bart guru? Is that the Dr M out of Maryland? He has some great presentations on youtube I know.
Keebler - thanks for your info. I plan on doing a few things to prevent otoxicity. I will be taking high does antioxidant supplements and IV glutathione to prevent / ameliorate this if possible.
If anyone is interested in studies regarding protection from Gent toxicity, I have put together a useful spreadsheet with this information. I am happy to send it to anyone who requests. Just let me know. The studies point to CoQ10,Alpha Lipoid Acid and NAC.
Posts: 70 | From New Jersey | Registered: Aug 2013
| IP: Logged |
TNT
Frequent Contributor (1K+ posts)
Member # 42349
posted
quote:Originally posted by kms1990: TNT - who is the bart guru? Is that the Dr M out of Maryland? He has some great presentations on youtube I know.
That's the one.
quote:Originally posted by kms1990: Keebler - thanks for your info. I plan on doing a few things to prevent otoxicity. I will be taking high does antioxidant supplements and IV glutathione to prevent / ameliorate this if possible.
If anyone is interested in studies regarding protection from Gent toxicity, I have put together a useful spreadsheet with this information. I am happy to send it to anyone who requests. Just let me know. The studies point to CoQ10,Alpha Lipoid Acid and NAC.
Sounds like you are going into this well-informed. I send my well-wishes and blessings and may you get completely well. If this really helps you, please come back and let us know. I've been curious about how this treatment goes for those who need it and do it.
Posts: 1308 | From Eastern USA | Registered: Oct 2013
| IP: Logged |
posted
Thanks TNT. I will report back on my experience. I will be on the medication for 14 days. Likely will also be on Doxy as well.
Posts: 70 | From New Jersey | Registered: Aug 2013
| IP: Logged |
posted
In regard to the bacteristatic vs bactericidal comment above, the distinction in and of itself is of no clinical significance. Both types of drugs characterized in this was from in vitro studies can and are beneficial to patients.
Posts: 360 | From Massachusetts | Registered: Dec 2012
| IP: Logged |
posted
Thank BobG. That makes sense. Its all individual. For me the bacteriostatic meds at high dose were just not doing the job. Someone who has been ill for a shorter period of time, or who has a less compromised immune status may do ok on them. I went at it hard for 12 months with some improvement but not major success.
Posts: 70 | From New Jersey | Registered: Aug 2013
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/
UBBFriend: Email this page to someone!
Printer-friendly view of this topic