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» LymeNet Flash » Questions and Discussion » Medical Questions » Anyone try SAM-e?

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Author Topic: Anyone try SAM-e?
Neko
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HELLLO,

I had the MTHFR test done and found I'm heterozygous for the mutation. Thus on paper my enzyme pathway would be operating at ~50% in theory.

I had a methylation test done and found out I am indeed under methylating. My doc recommended sam-e, methyl folate and a form of b-6.

Has anyone else tried this? I have suffered from chronic low grade depression my whole life so the Sam-e supplement sounds promising. I went off my antidepressants so I'm able to do a high dose of Sam-e and it has helped my mood a bit. I know you need to be careful taking Sam-e and SSRIs due to serotonin sickness.

But I haven't head much about sam-e here and it might be useful for some Lyme sufferors and those with mild to moderate depression that aren't being treated with antidepressants.

Anyone try it?

The price if Sam-e is a little outrageous though!

Posts: 133 | From North Shore | Registered: Sep 2015  |  IP: Logged | Report this post to a Moderator
MichaelTampa
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I took it some years back, before I started getting some decent lyme treatment (before I was diagnosed with lyme). I felt it was pretty good.
Posts: 1927 | From se usa | Registered: Mar 2010  |  IP: Logged | Report this post to a Moderator
Rumigirl
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I've taken it for years; it is good.

Now brand, or Life Extension, has cheaper prices. I think Now is cheaper. It's still not cheap, but relatively cheaper.

You can also take TMG, which is cheap, which is supposed to turn into Sam-e. I do both. That way, you can get away with a little less Sam-e.

Watch out for getting too hyper if you take too much of either, though.

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bluelyme
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Ya helped depression but anxiety was up ...like a person with out arms i just couldnt hang ...

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