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» LymeNet Flash » Questions and Discussion » Medical Questions » How much NAC can you take ?

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Author Topic: How much NAC can you take ?
MannaMe
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Is there an upper limit on how much you can take?

Can too much cause any problems?

Posts: 2248 | From USA | Registered: Aug 2011  |  IP: Logged | Report this post to a Moderator
tulips
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I successfully took one with each of my 3 daily meals but felt really weird one day when I took it at the same time as another supplement. I'd recommend allowing about 20 minutes I between taking something else.
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tulips
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I successfully took one with each of my 3 daily meals but felt really weird one day when I took it at the same time as another supplement. I'd recommend allowing about 20 minutes I between taking something else.
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bluelyme
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It can kill off cpn acording to cpnhelp.org. ..

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Blue

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bluelyme
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It can kill off cpn acording to cpnhelp.org. ..

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Blue

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dbpei
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It seems to give me a feeling of low blood sugar a few hours after breakfast (weakness, shakiness and hunger) if I take it in the morning. For that reason, I take it with my lunch, along with other supplements. I seem to tolerate better at this time.

I did not know you were supposed to separate it from other meds. I have never taken more than 1 dose a day.

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Keebler
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NAC: of N-acetyl cysteine

Just stumbled upon this:

http://www.betterhealthguy.com/klinghardt-2016

Dr. K. Conference Notes - compiled by Scott F.
12 July 2016

nearly 2/3 of the way down:

. . . NAC should generally be used only for short periods of time. You can destroy biofilms in the gut and acquire leaky gut from it. It breaks down biofilms, but also impacts the gut as well. High does of NAC are not a good option generally. . . .
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[ 04-02-2017, 04:22 PM: Message edited by: Keebler ]

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Keebler
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NAC: of N-acetyl cysteine

Yet, there are some good considerations to NAC as well.


Yet how NAC can impact the lining of the gut and cause / worsen "leaky gut" is one very important consideration, of course.

Beyond, along with or maybe separate from (?) NAC's properly to help the liver make the ever vital GLUTATHIONE is

NAC's property to help "melt" (my word) BIOFILM. The CpnHelp website and the Stratton / w (sp?) doctors who devised the protocol for Chlamydia pneumonia find that NAC can help lessen BIOFILM in treatment of Cpn . . .

much like BIOFILM issues with lyme (as really many bacteria, maybe viruses, too? - have biofilm protective measures "built in" to their biology so some Rx just can't get to them.

Attending to BIOFILM is really important. But it has to be measured. And - IMO - NO treatment should ever cause holes in our stomach lining.

So some things need to be worked out regardless of WHY one might be considering NAC, all it's properties and propensities must be considered.


Yet, there are some good considerations to NAC as well -- yet not mentioned for those who might not be able to tolerate it's harsh stomach effects or for other reasons is that

there are many other good options for liver support that also help increase / maximize glutathione in the body. Milk Thistle and Dandelion, Bupleurum, etc.

And there may be things that would help the gut be able to better tolerate NAC. Slippery Elm Bark powder / lozenge; DGL; Marshmallow Root are just a few things that come to mind.

For consideration, though:


https://www.tinnitusformula.com/library/nac-for-tinnitus-and-your-health/

NAC for Tinnitus and Your Health

By Barry Keate

For years I have recommend the use of N-acetyl cysteine (NAC) to individuals with recent exposure to loud noise or ototoxic medications for protection against increased tinnitus and hearing loss.

NAC must be taken either before or shortly after such exposures in order to be effective.

I have discussed some of the uses of NAC in an earlier article on antioxidants and brain calming supplements and have featured its benefits in numerous Ask Barry questions.

Until now I have not outlined all the health and protective benefits of NAC in one paper.

NAC is a stable form of the sulfur containing amino acid cysteine.

It is a powerful antioxidant and precursor to glutathione, the body’s primary antioxidant and free radical scavenger.

There are many wonderful benefits of this supplement and we will discuss all of them. NAC is an inexpensive dietary supplement found in most health food stores.


Noise-Induced Hearing Loss and Tinnitus
Researchers have known for many years that high-level noise induces oxidative stress in the cochlea.

*** It does this by causing a decrease in blood flow, releasing excessive amounts of glutamate, a toxic excitatory neurotransmitter, and stressing the mitochondria. ***


[poster's interjection: note the mention of glutamate being so harmful.]


Oxygen free radicals are thereby generated in the cochlea. Free radicals are toxic to the hair cells and neurons in the auditory pathway. (1)

NAC can be used by the body to make glutathione, the body’s own antioxidant defense. When a loud noise occurs, glutathione levels drop because it is trying to counteract those toxic free radicals.

After awhile, glutathione becomes depleted. NAC can be taken up by the body and used to re-synthesize more glutathione, which is then available to act as the natural antioxidant to reduce the stress and neutralize the toxins.

Several studies in both animals and humans have shown the protective effects of NAC against noise-induced hearing loss. . . .


. . . Ototoxic Medications

There are over 200 ototoxic medications, both prescription and over-the-counter, that can damage hearing and cause tinnitus.

[poster's interjection: Neil G. Bauman's more recent book "Ototoxic Drugs" references hundreds more that Keate noted at the time of the writing.]


The mechanism of action seems to be similar to that of noise trauma; the drugs potentiate glutamate receptors in the cochlea that promote degradation of hair cells and neurons.

This in turn leads to a cascade of free radicals, which further destroys the hair cells and neurons.

Once again, NAC is found to be very helpful in reducing the incidence of increased hearing loss and tinnitus if used prior to or very shortly after exposure. . . .

. . . . [Full article at link above. Well worth reading. This is an EXCELLENT article full of all kinds of valuable detail.]
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Keebler
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To help with GLUTATHIONE matters, there are various choices:

http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=3;t=030792;p=0

LIVER & KIDNEY SUPPORT
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Keebler
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To help mitigate "leaky gut" if one choose to take NAC, there are some good links in here.

First, though a GLUTEN FREE DIET is often really important to help the lining of the gut. Whether or not celiac is an official diagnosis, perhaps yet to be determined or not.

Look for the links about SLIPPERY ELM, MARSHMALLOW ROOT, DGL:

http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=1;t=119808;p=0

Topic: Treatment / Support for Gastroparesis

Many great links here
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Keebler
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Oh, no, I just put all those in the wrong thread! This was in reply to a "hearing loss" thread but it still good to have it in this NAC thread for further reference so I'll keep it here.
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willbeatthis
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Hi Keebler- Thanks for the info from Dr. K as I never could take this stuff- ALWAYS hurt my stomach.
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