LymeNet Flash: Flucanazole.. (diflucan) kills lyme or just yeast?

This is topic Flucanazole.. (diflucan) kills lyme or just yeast? in forum Medical Questions at LymeNet Flash.

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Posted by niki (Member # 7720) on :

I am starting abx treatment for lyme next week hopefully. Bit twenty years ago just diagnosed. I have nuero lyme and have been on Flucanazole for almost two months for systemic yeast that I now know was caused by lyme. I have felt pretty crappy while on it. Started taking it after four months of anti yeast diet and lots of nystatin. Started on it because I wanted something that would go into my brain.

So now I am wondering if it Kills lyme bacteria as well. I know it is used in treatment but as a candida sufferer I know getting rid of yeast can improve lyme symptoms.

So is it used to just clean up the body after abx?
Is that why symptoms improve and people herx and have die off?
Just from the yeast alone?

I would love to have some report that it kills lyme because that would mean I started treamant two months ago and not in a week! Any one have any more info on this?

Posted by Lymetoo (Member # 743) on :

I agree with Lyme ED....exactly. And I too, had yeast problems caused by Lyme and began my yeast treatment several months prior to beginning abx.

I think the Diflucan works mostly on the yeast, not the Lyme, but that's simply an opinion. I think alot of folks THINK they don't have yeast.....so when the Diflucan makes them better, they think it's killing keets. [Those would be people who are on abx that I'm talking about.]

It is a known fact that Diflucan and other anti-yeast drugs and natural products DO cause die-off, with similar symptoms to Lyme.

Candida elimination: http://flash.lymenet.org/ubb/Forum1/HTML/021412.html
Lyme symptoms list compared with yeast symptoms http://flash.lymenet.org/ubb/Forum1/HTML/021202.html

Either way, you're way ahead of the game, niki!

------------------
Do not take anything I say as medical advice. I am not a doctor, but I DID stay at a Holiday Inn Express!
oops!
Lymetutu

Posted by burnbitter (Member # 7088) on :

I didn't find that the diflucan helped at all. It did seem like it caused some additional side effects, but at the point I added that on as a daily med I was on a lot of things so it's hard to tell.
It didn't make me magically better. I don't feel I had much of a yeast problem.

Posted by jloisu (Member # 7538) on :

Ok...so here's what I know. As far as Diflucan is concerned, I have had great luck w/it helping my GI problems. That aside, there is the reseach done by Schardt, who through his research has found that Diflucan blocks some pathways needed for Lyme to reproduce (from what I remember). I can send you the paper (I have it in pdf form only).

Anyone who is interested in reading this paper please email me and I will pass it along as I don't know how else to post it since it is a pdf that was sent to me by Dr. S. T. who is working w/Diflucan here in Iowa.

jloisu

[This message has been edited by jloisu (edited 31 August 2005).]

Posted by bg (Member # 46416) on :

Lois, I just sent you a private email asking you for the paper that Scott wrote. Been on diflucan since 3-05.

bettyg, Iowa

Posted by Corgilla (Member # 4066) on :

Hi jloisu,

I sent an email too.

My LLMD said that diflucan works on the same pathway that Ketek does. Would be interested in the paper to check that out.

Thanks,

Corgilla

Posted by jloisu (Member # 7538) on :

I will get this paper out to you ASAP.

jloisu

Posted by Nancy2 (Member # 95) on :

My niece's LLMD, the great Dr. P of CT, is very excited about its use, and is beginning to use it with his patients, altho he wants one off of ALL ABX when taking it!

NANCY

Posted by GiGi (Member # 259) on :

Maybe Oxygenbabe can post her interview with Dr. Schardt. It is of a more recent date and a 50 day treatment period.

Eur J Med Res. 2004 Jul 30;9(7):334-6. _Related Articles,_
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Display&dopt= pubmed_pubmed&from_ uid=15337633)

Clinical effects of fluconazole in patients with neuroborreliosis.
Schardt FW.

Betriebsarztliche Untersuchungsstelle, Bayerische Julius-Maximilians-Universitat, Wurzburg, Germany.
[email protected]

Eleven patients with neuro-borreliosis had been treated with 200 mg fluconazole daily for 25 days after an unsuccessful therapy with antibiotics.

At the end of treatment eight patients had no borreliosis symptoms and remained free of relapse in a follow-up examination one year later.

In the remaining four patients, symptoms were considerably improved. At the end of therapy immune reactivity (IgM+) disappeared in three patients.

Since borrelia spp. are almost exclusively localised intracellular, they may depend on certain metabolites of their eucaryotic host cell.

Inhibition of P450 and other cytochromes by fluconazole may incapacitate Borrelia upon longterm exposure.