What does Band 63 stand for in the western blot? Thanks, Robin
Posted by Mathias (Member # 5298) on :
Have never heard of band 63 being relevant to lyme disease. 60 and 66 are more commonly looked at and 66 is one of the 10 bands for CDC IgG criteria.
[ 05. March 2006, 10:15 PM: Message edited by: Mathias ]
Posted by Gretchen P (Member # 8403) on :
Here is the Western Blot result interpretation:
9 cross-reactive for Borrellia 12 specific for Bb 18 unknown 20 cross-reactive for Borrellia 21 unknown 22 specific for Bb, probably really the 23/25 band 23-25 outer surface protein C (OspC), specific for Bb 28 unknown 30 unknown; probably an outer surface protein; common in European and one California strain 31 outer surface protein A (OspA), specific for Bb 34 outer surface protein B (OspB); specific for Bb 35 specific for Bb 37 specific for Bb 38 cross-reactive for Bb 39 is a major protein of Bb flagellin; specific for Bb 41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia 45 cross-reactive for all Borellia (sometimes people with Lyme who have this band positive also have the co-infection Ehrlichiosis) 50 cross-reactive for all Borrellia 55 cross-reactive for all Borrellia 57 cross-reactive for all Borrellia 58 unknown but may be a heat-shock Bb protein 60 cross reactive for all Borrellia 66 cross-reactive for all Borrelia, common in all bacteria 83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane 93 unknown, probably the same protein in band 83, just migrates differently in some patients
I hope this helps you I always pay particular attention to the lyme specific bands. Peace!
Posted by Robin61 (Member # 5470) on :