This is topic Band 63 in forum Medical Questions at LymeNet Flash.


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Posted by Robin61 (Member # 5470) on :
 
What does Band 63 stand for in the western blot? Thanks, Robin
 
Posted by Mathias (Member # 5298) on :
 
Have never heard of band 63 being relevant to lyme disease. 60 and 66 are more commonly looked at and 66 is one of the 10 bands for CDC IgG criteria.

[ 05. March 2006, 10:15 PM: Message edited by: Mathias ]
 
Posted by Gretchen P (Member # 8403) on :
 
Here is the Western Blot result interpretation:

WESTERN BLOT

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

I hope this helps you I always pay particular attention to the lyme specific bands. Peace!
 
Posted by Robin61 (Member # 5470) on :
 
Thanks everyone!Robin in Houston
 


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