Who else is on IV Clindamycin?
Posted by Melanie Reber (Member # 3707) on :
Hey AP,
I'm not on it now but did quite a bit a couple of years ago.
M
Posted by 5dana8 (Member # 7935) on :
Not on it now but did it on Iv 3 years ago.
Herx's from hell and made me deeply depressed.
But I feel it did help turn me around.
take care
Posted by AP (Member # 8430) on :
Did it give anyone really bad gas? If so, how the heck did you get rid of it?
Posted by robi (Member # 5547) on :
How do you get rid of really bad gas???
Umm welll, you go to another room .......
I must think I am funny ..... my mom used to tell me that ...... "you must think you're funny!" she was not smiling when she said it.
Just in a goofy mood, robi
Posted by LYMESCIENCE (Member # 9259) on :
I'm a bit split on this drug. While it could theortically be an excellent cyst buster. I think its a very bad drug to give unless a person either has been well treated previously for Babesia, or does not have Babeisa.
If those conditions are met, then I think it has lots of potential.
Posted by char (Member # 8315) on :
My hunch us it is related more to the recent GB removal. Sent pm.
Char
Posted by Melanie Reber (Member # 3707) on :
Lyme Science,
Will you please explain further your thinking on that?
AP,
I don't remember having that reaction to Cleocin. I do remember it effecting me in other ways though. It made me very cold as I infused, and very tired. It also caused a bit of a racing heart.
At the time, I was also on IV Rocephin, then switched to IV Zith...along with allot of other stuff.
Robi,
Thanks for the smile- you really ARE funny no matter what your mom says.
M
Posted by AP (Member # 8430) on :
Robi, at some point, we run out of rooms, or if you run too fast, it follows. It's pretty bad when the dog is the first one out the door.....
I don't have any coinfections.
My hands get unbearably cold when I infuse. I normally wrap myself in a big cozy blanket, and infusion only takes 30 minutes or so, but with this new pediatric PICC infusion can take up to an hour (per drug, currently on Primaxin and Clindamycin). They might as well send me to antarctica.
Posted by LYMESCIENCE (Member # 9259) on :
Ahhh AP, so you are at seeing Dr. J in NC. I feel ya. If I were you, I'd delete that no co-infections comment. Its more than likely not factually based. But, you'll discover this to be true in this course of your therapy. Live and learn, and then get Luvs, as the commercial for diapers says. For Lyme it might as well be Live and Learn, and then realized you were co-infected:)
Posted by AP (Member # 8430) on :
quote:Originally posted by LYMESCIENCE: Ahhh AP, so you are at seeing Dr. J in NC. I feel ya. If I were you, I'd delete that no co-infections comment. Its more than likely not factually based. But, you'll discover this to be true in this course of your therapy. Live and learn, and then get Luvs, as the commercial for diapers says. For Lyme it might as well be Live and Learn, and then realized you were co-infected:)
And WHO are you?
Posted by LYMESCIENCE (Member # 9259) on :
Melanie Reber,
Sure, I'll explain my reasoning. First as a cyst buster. One of the postulated reasons why Tindamax and Flagyl work is that they are highly anerobicly active. The thought is that these cysts are aneraerobic gram negative bacteria. Since Tinda/Flagly are active against almost all gram neg and gram + anerobes, the thought is that this is their mechanism of action.
Clindamyacin is a highly effectly antibiotic against anerobic gram negative bacteria. While it does not have the range of activity into gram positve anerobes found in Tinda, its activity against gram negative anerobes is in many cases stronger than Flagly or tinda.
However, the cyst activity of Clinda is assuming that the cyst is a gram negative anerobe. I don't think anyone really knows if its gram neg or gram pos.
Borrelia, in its spiral form, is traditionally stained very weakly with a gram stain producing results consistant with a gram negative bacteria.
However, scientists have found that the antibiotic sensitivity of Borrelia B. is highly inconsistant. Its behavior in the face of antimicrobials is unilike any other gram negative bacteria known to man.
For example, Borrelia Burgdorrferi is highly susceptable to Vancomyacin. This should be nearly impossible as Vancomyacin was designed to work almost exclusivly on gram positve bacteria.
Scientists still have no idea why Vanco, a drug exclusivly for gram pos infections (except in very rare cases) works on Borrelia Burgdofferi.
So, that comes the question, is the cyst gram negaitve, and even if it is, does that even matter. It may not be susecptable to Clinda even if it is a gram negative.
Posted by Melanie Reber (Member # 3707) on :
Thanks Science,
I understand your reasoning on the pos-neg effects of Cleocin with Bb...but am even more curious about this statement:
"I think its a very bad drug to give unless a person either has been well treated previously for Babesia, or does not have Babeisa"
What does that have to do with treating Babs?
M
M
Posted by 5dana8 (Member # 7935) on :
Hey AP
I do feel for you with the gas problem. I couldn't even stand to be around myself!
Just a thought on the gas issue. Are you taking enough pro-biotics? Anti-yeast diet?
Intestional gas can mean different causes for different people.
When it got to biblical proportions and really foul this was a tip off for me of yeast and that the abx was killing off too many of my good flora too.
I like theralac now. I take it every other day and mix it up with my other probiotics.
I also think the kefir and yogurt are helping too.
In the past intestional gas was a sign for me of yeast.
The only over the counter remady I found to work for me was Phazime (sp?)
Usually 2 weeks diflucan cleared it up.
hope you can feel better soon
Posted by AP (Member # 8430) on :
Thank you Dana... I take lots of probiotics, I've been told you can't take enough.
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