This is topic my doc is pulsing Mepron for babs in forum Medical Questions at LymeNet Flash.


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Posted by mtnwoman (Member # 8385) on :
 
We are going to start empiric tx for babs after a year of other abx with so-so improvement.

He recommends Mepron 1 tsp 2x/d + Zith 500mg 2x/d, 3 weeks on (only Mon thru Fri) and then the 4th week is off all meds. In 3rd week add tinidazole 500 mg bid. Repeat x 3 cycles of this.

Has anyone done a similar protocol and improved? Any concerns re the one week rest week after 3 weeks on?

thanks in advance for your comments!
 

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Posted by AliG (Member # 9734) on :
 
Anyone else hear of this?
Sorry, I haven't, not sure what to think.
Hope it works for you.
 

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Posted by 5dana8 (Member # 7935) on :
 
I had to pulse my babs meds including the mepron-for stomach issues.

Herxed hard enough & did seem to get rid of alot of my babs symptoms. Specially it finally got rid of my low grade fevers that I had had for 20 years.

Good luck with your treatment
Hugs & healing
Dana
 

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Posted by mtnwoman (Member # 8385) on :
 
Re. taking week four off after 3 weeks on Mepron (as advised by my LLMD) I see that it does have a long half life:

quote:

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The half-life of atovaquone was 62.5 � 35.3 hours after IV administration and ranged from 67.0 � 33.4 to 77.6 � 23.1 hours across studies following administration of MEPRON Suspension . The half-life of atovaquone is long due to presumed enterohepatic cycling and eventual fecal elimination.

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