This is topic Grapefruite or grapefruit seed extract in forum Medical Questions at LymeNet Flash.


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Posted by mag (Member # 8920) on :
 
Hi Everyone and the Grapefruit lovers

There was a recent post on this ... and all the
preservatives added, etc.,

I usually herx a bit after eating a whole grapefruit ---seed and all. So I know it works for me..

This information describes the process for extraction and the natural benzyl chloride .....


http://www.itmonline.org/jintu/grapefruit.htm

Grapefruit seed Extract...it is synthesized from the polyphenolic (flavonoid) compounds found in the mixture of grapefruit seeds and pulp that is left over from production of grapefruit juice. The manufacture is described as follows:

Grapefruit pulp and seed is dried and ground into a fine powder.
The powder is dissolved in purified water and distilled to remove the fiber and pectin.

The distilled slurry is spray dried at low temperatures forming a concentrated flavonoid powder.

This concentrated powder is dissolved in vegetable glycerine and heated.
Food grade ammonium chloride and ascorbic acid are added, and this mixture is heated under pressure.

The main active components in the finished product are a group of quaternary ammonium chlorides, including benzethonium chloride or a compound nearly identical to it, that make up about 8-17% of the product.

Benzethonium chloride is a well-known synthetic antiseptic agent; it is not added to the grapefruit extract, but is formed from the original grapefruit flavonoids by the ammoniation process

mags
 
Posted by 5dana8 (Member # 7935) on :
 
Thanks Mag for posting the info on GSE [Smile]

I'll have to try eating the whole grape fruit if my tummy will allow me some citrus.

This may sound like a whacky question but
do you eat the skin too as well as the seeds?

I pulse the GSE every month & the only side effect other than usual herxing synptoms are worse dry eyes. Do you get this too?

Blessings [Smile]
Dana
 
Posted by mag (Member # 8920) on :
 
hi 5dana,

just had one of those grapefruits -

i eat the pulp and seeds ( you can split the seeds out of the shell) some of the white part too although it is bitter!

I has not bothered my stomach -
I have the GSE too- but do not take it -


mags
 
Posted by mag (Member # 8920) on :
 
And more on the grapefruit

"The juice of grapefruit is an excellent remedy for influenza as it helps in reducing the acidity in system and its bitter properties arising from a substance called `Marin gin, tones the system up. It quenches thirst and removes the burning sensation of fever."

"It contains natural `quinine' and hence is valuable in the treatment of malaria. This `quinine' is also beneficial in feverish colds. It can be extracted from fruits by boiling a quarter of a grapefruit and straining the pulp. It is beneficial in the treatment of fatigue. Taking a glass of grapefruit and lemon juice in equal parts is an excellent way of dispelling fatigue and general tiredness after a day's work."

mags
 
Posted by Dave6002 (Member # 9064) on :
 
Mag,

Good information.

I'd like to try it using a blender to liquefy the seeds and pulp of a grapefruit.

I found that I can get very strong garlic juice: I can barely tolerate 3 or 4 clovers of garlic.

I may need to reduce to 2 coves.

Dave

[ 04. March 2007, 05:21 AM: Message edited by: Dave6002 ]
 
Posted by mag (Member # 8920) on :
 
dave

Juicing the grapefruit doesn't taste as good as
eating with a spoon

do you use the pulp from the garlic ?

mags
 
Posted by groovy2 (Member # 6304) on :
 
Hi All

I tried brushing my teeth with
straight GSE --LOL

It was a BIG mistake --OUCH---

Also --
If you are taking Doxi --
the GSE (Citrus)can cause bad Photo Toxic reaction--

No Citrus of any kind should be eaten
while taking Doxi--

I know I am starting to sound like a
broken record but I dont want anyone to
go thew what I did--

It was Horriable--Not Kidding --Jay--
 
Posted by catalysT (Member # 10786) on :
 
Yes LymeED, grapefruit contains potent CYP3A4 Inhibitors, such as quercetin, bergamottin, etc.

Cyp3a4 is a metabolism enzyme..

You can find a decent list of CYP3A4 Inducers, Inhibitors, and Substrates on wikipedia.

http://en.wikipedia.org/wiki/CYP3A4

Also note that there can be CYP3a4 in different parts of elimination, liver, etc?

Taking a cyp3a4 inhibitor or inducer, with a substrate (drug that is dependant on cyp3a4 for its metabolism) can be dangerous, or render the drug ineffective.

I think provigil may be a cyp3a4 inducer, not sure.
 
Posted by Dave6002 (Member # 9064) on :
 
Mag, yes, I take everything when I use a blender to liquefy garlic.

Eating grapefruit seeds may not taste good either unless you swallow them like pills, which may not be effective.

My point is that liquefied grapefruit would be much more effective.

So artemisinin is metabolized by CYP3A4?

cause some say grapefruit can greatly enhance the effectiveness of Arte.

Dave
 
Posted by clairenotes (Member # 10392) on :
 
I think it would be good to throw in as much of the white part of the grapefruit as possible. The inside of the rind is so rich in bioflavonoids. Wonder if the skin has some value, too?

Claire
 


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