This is topic Extreme sleepiness on Rifampin--side effect or herx? Does it go away? in forum Medical Questions at LymeNet Flash.


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Posted by Hoosiers51 (Member # 15759) on :
 
I have recently upped my Rifampin to 600mg (a couple days ago) and I am sooooo sleepy. I think I read this can be a side effect, but I also read that on Rifampin you can expect improvement on the second or third week.

I am SO sleepy that it is scary. All I want to do is sleep. I am too drowsy to prepare food, make phone calls, etc. At any given moment, I could sleep.

To Rifampin users--did this get better for you? At what point? Like around the 3 week mark? Did it get better for anyone beyond 2 months? (just so i would know so i wouldn't stop it too early)

Thanks!
 
Posted by lymephobic (Member # 17556) on :
 
This hasn't happened to me on Rifampin. I hope it stops for you soon though.
 
Posted by lymeinhell (Member # 4622) on :
 
I seem to recall getting hit with the 'OMG, I have to lay down this second I'm so tired' kind of sleepiness in the early months. It would just hit out of nowhere.

I can't recall exactly when the sleepies stopped hitting me.

Expecting results after 2 or 3 weeks is just setting your hopes a bit too high.

If you haven't had a full blown herx yet, you could be in for some tough days. Keep a symptom calendar - you may find your herxing cycle is at exact time periods (such as every 28 days).

But, I do recall Month 4 seemed to be the turning point for me on it. The monthly herxing in months 1, 2 and 3 were pretty brutal, but I do recall after month 2 seeming just a teensy bit better after the herx.

Stick with it if you can. Remember to detox and take milk thistle, as Rifampin is hard on the liver.

BTW - I did get better on it and have my life back.
 
Posted by Rianna (Member # 11038) on :
 
Rifampin can change your SHBG (sex hormone binding globulin) my doc told me to ensure i got mine checked pre and post rifampin.

If it effects your SHBG it can make you very tired so its worth getting it checked out

Rianna
 


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