I can't believe this is not written on the stickers on the prescription bottles. I also couldn't easily find anything about it on the written
information that comes with the prescrption (although it's very wordy and I didn't read it all).
How do magnesium and calcium interfere with medication absorption?
Posted by btmb03 (Member # 18394) on :
Ali is probably right but I take my biaxin after b'fast with calcium and other supps but not magnesium which I take at lunch.
So far no probs, but the biaxin sure does pack a punch!!
Posted by AliG (Member # 9734) on :
Sorry, too tired right now.
Thought this would be an easy answer & didn't realize I was going to need a full-blown explanation with links & citing of research.
I'll try to research it for you later, if I have any strength.
Maybe someone else has info on minerals & abx handy.
Posted by AliG (Member # 9734) on :
egg on my face
I researched & can't figure out where I came up with that.
I don't know whether it was the product of a conversation with my LLMD or pharmacist and/or perhaps I misunderstood something.
I found interactions for Tetracyclines & Floroquinolones & some ABX can cause an increased uptake of calcium but I don't remember which.
I meant to go back & find it because I thought that it might be good information to know. Maybe tomorrow.
I could swear I got that information from somewhere. Maybe it was an antiquated nursing book or something.
I would think that calcium's effect on the stomach's acidity might effect digestion and magnesium's laxative effect, speeding GI transit time might impact the uptake of the drugs, but I guess I've got nothing to back it up.
I guess I DON'T know what I'm talking about. I think I'll go back to bed & stop answering posts, lest I say something else stupid.
THIS is why it's good to always double-check your sources, especially when some of them may have neurological Lyme.
Posted by Bobidor (Member # 14453) on :
Magnesium and calcium can significantly reduce the bioavailability of several antibiotics.
According to a document from Pacific Frontier Medical http://www.pacificfrontiermedical.com/pdfs/19.pdf , we're not supposed to take multi-mineral supplements or antacids 1 hour before or after taking macrolides abx (Biaxin, Zithromax...)
My LLMD says we should wait even longer (2-3 hours).