[ 01-07-2010, 01:22 PM: Message edited by: emla999/Lyme ]
Posted by pryorka (Member # 13649) on :
Why does he say it's an infection, and then says it's zinc and B6 deficiency just like KPU?
Posted by emla999/Lyme (Member # 12606) on :
Pyroluria and KPU are the same thing. And if I understand the author correctly he is saying that pyroluria (KPU) is not caused by your genetic's but rather it is caused by a bacteria or another pathogen of some sort.
The author also seems to be saying that the bacteria or pathogen that causes pyroluria (KPU) is what really causes the vitamin B6 and Zinc deficiencies that are associated with pyroluria (KPU). And taking more zinc and B6 helps to alleviate the symptoms associated with pyroluria (KPU) but to permanently cure pyroluria (KPU)you need kill the pathogen within your body that is causing the pyroluria (KPU)to begin with.
Posted by SForsgren (Member # 7686) on :
The Klinghardt article in Explore! also suggests that infection can be the trigger for KPU.
Posted by SForsgren (Member # 7686) on :
Thanks for the link to the book btw. It is a topic I am very interested in.
Posted by lymie_in_md (Member # 14197) on :
I am too! Thanks for posting.
Posted by pryorka (Member # 13649) on :
That book is very different from what all the literature on kryptopyrroluria says. I've seen slides of charts dr. k has put together with metabolic flow charts on them showing how KPU affects certain reactions in the body. The author of this book however doesn't seem to understand all the information or even the basic studies done back when KPU was discovered. So something seems very off to me.
Posted by lymie_in_md (Member # 14197) on :
It's probably an evolving protocol. As many patients show progress the doctors who are using the protocol are adjusting and then talking with each other about the adjustments. The latest protocol is the last one written.
Posted by Keebler (Member # 12673) on :
- Thanks for finding that new ebook, Emla.
--
In an attempt to address a question above, porphyria can be genetic OR caused by toxins (from infection or chemicals).
But it's not to be considered an infection itself nor even just a vitamin or mineral deficiency (as that becomes the result of the damage of dysfunction).
However, if infection is present, only by treating infection does the patient have a chance at calming porphyria symptoms or, if lucky, eliminating the propensity of elevated porphyrins that can kill cells in the body.
If vitamin or minerals are deficient, replacement therapy is vital.
Actually, every kind of porphryia is a dysfunction of the liver - either 1) DEFICIENCY or 2) a total INABILITY of the liver to make the very precise enzymes - or group of enzymes- necessary to metabolize certain chemicals.
As there are over 11 kinds of porphyria (and some subsets to those) . . . the type depends on which enzymes are absent or deficient as each enzyme is responsible for different chemical metabolism.
Any porphyria can be genetic (in your genes) or in someone with a liver malfunction from other causes.
Some kinds of porphyria can be acquired from chemical exposure (or even from some medicines) that damages the liver - or from infection that damages the liver's capacity to produce the key enzymes.
This process can affect heme, a part of blood, so to speak. When heme is affected, a cascade of other problems develop and this enzyme/liver/blood dysfunction can also cause so many other things to go wrong.
These very specific enzymes are unlike digestive - or pancreatic - enzymes that can be taken in capsules. These liver enzymes related to porphyria are not available commercially so there is currently no dietary enzyme to correct this.
Still, the researchers focusing on KPU/HPU are onto something, I truly think.
Certian dietary measures, some vitamins and nutritional supplements (and some herbs such as schizandra, milk thistle, etc.) can help the liver to work better, thereby, improving the liver's capacity to make those enzymes again.
If the liver is totally damaged in this regard, replenishing nutrients will still be important but the liver may never regain its ability to manufacture needed enzymes.
Also to keep in mind: some of these "sub-sets" may have developed not necessarily first from liver dysfunction but by poor nutrition. If the liver has not been given the nutrients it needs, it simply cannot do its job. So, in that sense, one might say this or that vitamin or nutrient causes porphryia but it's still really the liver dysfunction that powers the cascade of events.
If the liver is well enough to receive what it needs, the hope is that it will work efficiently again. Unfortunately, for lyme patients, it is very complex since so many medicines are so hard on the liver.
I wish I could explain this as the specialist who taught me so much but I have to stop there, with an incomplete description and wishing that I had a better command of language and a brain not of molasses. But I don't so . . .
. . . for more detail, see the links to the Canadian and American Porphyria groups at this thread: