Our daughter has been on 100mg of mino and 600mg of Rifampin.
three month into treatment her Alt was normal (Sept), now her Alt is 104( dec. labs) -- normal being 0-35.
Dr.'s office said ASt and GGt are normal. I think the Rifampin is the cause.
They do not seem worried. I am!!! She is nauseaous lately too.
I asked in beginning of treatment about adding Milk thistle and the LLMD said he does not use it.
She had watery stools two days before labs. i wonder if that may have caused elavation?
Doctor's office said to increase probiotics for nausea and stay at half dose of antibiotics.
She has had more nausea lately. Had to stop antibiotics for over a week due to diarrhea last month.
Now having trouble getting back up to full dose. Dr. had her at half dose due to increased nausea. Now the labs results and the nurse is not concerned as Ast , etc are normal.
I think I need to research and see if she can take Milk thistle with Rifampin.
I am so worried now.
[ 01-12-2010, 06:41 PM: Message edited by: Jane2904 ]
Posted by B4LYME (Member # 23222) on :
I took mino for 2 weeks and had to stop because I was dizzy, nauseous, moody, etc. I heard from someone else here that they had the same experience. I stopped the mino and did feel better.
Now I'm on biaxin, im rocephin, im bicillin and added doxy a few weeks ago. I thought I'd have more problems with the biaxin but I didn't.
The doxy has been kicking my butt I think. I have rocky mountain spotted fever and some other coinfections. My theory with doxy is that it is active against lyme and many of the coinfections and so hitting all of that at once can do a job on you. Mino can affect all those coninfections at once too and is thought by some to be even stronger on some than doxy.
I take milk thistle, dandelion and just started N acetyl cysteine to support my liver. I think it's mepron you don't take milk thistle with, but hopefully someone else will respond to that.
I also take nystatin 3x a day for yeast and sometime diflucan.
As for the nausea, I use ginger capsules and they work well for me. I take them in the morning before my meds. I also take the doxy after my stomach has something in it for a little while in the mornings. In the evenings, my meal is bigger and I can take it right after I eat.
I hope this helps some and that others can help more.
B4LYME
Posted by street129 (Member # 23472) on :
i take milk thistle, and dandelion tea for my liver also, i believe i should get a liver cleanse.
got to look into N acetyl cysteine, i dont know what this is for....i'll google.
Posted by Jane2904 (Member # 15917) on :
Thank you B4Lyme and Street.
Hope you both feel better too.
Posted by Jane2904 (Member # 15917) on :
any one else have high alt on Rifampin?
Posted by Stacyb (Member # 13084) on :
I had high AST from Rifampin and took Milk Thistle and NAC and ALA to get mine to come back down to normal range. I also used Zhang's Hep-F #2 caps for liver support.
![[Frown]](frown.gif)