I was on cyanocobalamin shots for 2 months with no problem then I switched to Methylcobalamin shots Oct 6th, all of a sudden a few days ago I noticed every injection site i have used in the last 2 weeks has come up bright red, itchy, swollen, hot.....why would that happen???
I was thinking allergy or what else could it be??.............
Posted by cactus (Member # 7347) on :
Ask your LLMD.
I often had bright red spots - like red kool aid under the skin almost, which was just the methylcobalamin itself. Changing the angle of the needle going in helped a bit, but basically - I was spotted while on B-12 shots.
If these spots are very itchy, swollen and hot though - I would ask your LLMD.
Posted by Florence1 (Member # 22960) on :
called the pharmacy and my dr....maybe an allergy to the preservative....going to switch me to preservative free..
i know what you mean about the red metyl under the skin but these are hot, itchy, swollen........7.5cm in size.......
so we think its a reaction........driving me crazy.........
Posted by Lymetoo (Member # 743) on :
I would say it's an allergy. Glad you are being switched to one without preservatives. It is more expensive, darn it!
Posted by Florence1 (Member # 22960) on :
i just paid $100 for the original one...the compounding pharmacy dont file insurance......wonder how much the preservative free will be...........
Posted by cactus (Member # 7347) on :
Oh good - glad you are switching. Can you take some benadryl in the meantime?
I forgot it was available with preservatives - mine were preservative-free also.
Try filing your ins - mine covered a portion. Not all of it, but the majority. So there's hope!
Posted by 'Kete-tracker (Member # 17189) on :
The "preservatives" tend to just be a pinch of salt [NaCl] & a dash of benzyl alcohol. (oh, wait... Halloween's over!) So... why not just go back on/to the "cyano" stuff?
Posted by Florence1 (Member # 22960) on :
he wants me on methyl because of toxicity....so i'll try the preservative free.......first and see how that goes...........
Posted by sk8ter (Member # 8671) on :
If you have the MTHFR gene you should not take Methyl..You should take the hydroxycolobin type. Sublinguals work just as well as shots says the latest info. The company who has a good hydroxy is Perque labs:
I too am on daily injections of methylcobalamin B12 for 30 days. I would not reccomend cyancobal to anyone because it contains small amounts of cyanide!
For anyone advised to take B12, I would suggest ordering from Infuserve. http://www.infuserveamerica.com/ They sell methylcobalamin shots that are pre-filled to the specific dosage your doctor prescribes.
Posted by jwall (Member # 22999) on :
sk8ter, I have the MTHR gene and my Dr. has prescribed the methyl B-12 shots. I also take Deplin which is a prescription folic acid and noticed in the warnings it said not to take it if you have the MTHR gene.
Do you know why? My Lyme Dr. never mentioned it. i feel pretty lousy with deplin, but B-12 shots seem to help me a lot.
Posted by karenl (Member # 17753) on :
I take the preservative free hydroxy and it is normal that I get big red purple stains which stay for 7-10 days. It is the color of the meds. But my stains are generall not itchy.
Posted by resaz (Member # 31131) on :
What is the MTHR gene and how in world do you know if you have it before you take the b12 methyl
Posted by Razzle (Member # 30398) on :
Yes, one can become toxic from the cyano- part of the cyanocobolamin, if one is taking a lot of huge doses. But the body actually does have a detox method for the cyano- part of cyanocobolamin, so smaller doses or sublingual cyanocobolamin shouldn't be a problem for most.
I have no financial connections with any companies/websites/doctors/clinics mentioned in this post.
Posted by Fordace (Member # 14874) on :
Of course being from NY, I could not order this test, such BullS%it....
Posted by Razzle (Member # 30398) on :
You might be able to order it through your doctor from Genova Diagnostics. They have several genetic profile tests, such as the DetoxiGenomic test, that may show the MTHFR gene. See http://www.gdx.net/product/10038 (I have no financial connections with this company or website).
Posted by scorpiogirl (Member # 31907) on :
quote:Originally posted by sk8ter: If you have the MTHFR gene you should not take Methyl..You should take the hydroxycolobin type. Sublinguals work just as well as shots says the latest info. The company who has a good hydroxy is Perque labs:
This is what my LLMD did too. Since she did not test me and have no idea if I have the MTHFR gene, she put me on the Hydroxocolobin instead of Methyl.
Posted by pme (Member # 31621) on :
I have had bad reactions to b12 shots so this is really helping me. Next week I am going to discuss this with my doc to see what other forms are available. It does help some of the neuro issues but it makes me groggy and irritable and psycho (at least in the form that I have received it in to date). So its not worth it to me.
Posted by disturbedme (Member # 12346) on :
"Sublinguals work just as well as shots says the latest info."
Not true for everyone. I have pernicious anemia and took sublingual B12 for years before I knew, and it didn't help with my symptoms of pernicious anemia at all.
I take B12 shots once a week. The methyl B12 is the best kind.
Posted by Lyme Elle (Member # 30884) on :
Maybe I am deluded but I believe that everyone has the MTHFR gene. The problem with coagulation, folic uptake and numerous other issues is a mutation in the MTHFR gene.
I also take deplin. Without it I cannot maintain ferritin stores or healthy iron levels.
Posted by Hambone (Member # 29535) on :
quote:Originally posted by Lyme Elle: I also take deplin. Without it I cannot maintain ferritin stores or healthy iron levels.
How does Deplin help your iron stores?
I am curious because I can't keep my iron levels up no matter how much iron I take.