I'm wondering if 200 micrograms of synthetic glucocorticoids is enough to compromise a lyme patient?
This is a specific question about triamcinolone, which has systemic activity of 70% through the nasal mucosa. (In constrast, fluticasone propionate only has 2% systemic bioavailability from intranasal application).
And what about topical betamethasone for dermatitis?
Posted by Keebler (Member # 12673) on :
- Unless a life threatening emergency (and under the care of a LLMD with added protections),
avoid steroids, even topicals and nasal sprays. Even in the sinus cavity, steroids can make lyme in your whole body worse.
There are far better ways to treat nasal issues as well as dermatitis. Even in a skin lotion, it can make lyme in your entire body much worse. It has happened to others and there is not point in taking such a risk. These questions are addressed in articles here:
Topic: what do STEROIDS actually do to those with lyme? Risks, long term damage discussed. Links. -
Posted by ohioperson22 (Member # 47837) on :
I read that thread, and two things don't make sense:
1. Ashwagandha LOWERS cortisol. Absolutely terrible for someone with critically-low cortisol.
2. The thread says that low dose CORTEF let the adrenals rest? Actually, usage causes a downregulation of endogenous cortisol production, and can suppress the HPTA, as well as cause adrenal atrophy. How do either of those things "help the adrenals rest."???
I'm also interested in scientific literature that 200 micrograms of a synthetic glucocorticoid interfered with the immune response against bacteria.
Posted by Keebler (Member # 12673) on :
. . . "Steroid Disaster" is a term coined by the pioneer of Lyme Treatment . . .
Corticosteroids are immune suppressants, the last thing a Lyme patient needs is to lower immunity. -
Posted by Keebler (Member # 12673) on :
- To answer questions number
1. Ashwagandha lowers cortisol ONLY when the body needs that action. Search: ADAPTOGEN
Many lyme patients have very high spikes of cortisol at times and this can be damaging. Ashwagandha is an adaptogen. Detail as to what that means and to better understand all of it, see Wilson's book and other links in that set.
2. It's all about the PHYSIOLOGICAL REPLACEMENT DOSE and no more - see Wilson's book & also:
Safe Uses of Cortisol by William Jefferies
You can get Wilson's book - and maybe Jefferies, too - through any US library - the interlibrary loan system or through various web vendors. -
Posted by TF (Member # 14183) on :
You said:
"I'm also interested in scientific literature that 200 micrograms of a synthetic glucocorticoid interfered with the immune response against bacteria."
What is the trade name of this one?
Posted by TF (Member # 14183) on :
Nasacort (Discontinued in U.S.)
Posted by desertwind (Member # 25256) on :
I use it and no problems. My llmd, Dr. H., said not an issue. Now, the 4 months of Dexamethasone I was on....totally different story.
Posted by Lymetoo (Member # 743) on :
Nasacort is discontinued?
Posted by TF (Member # 14183) on :
![[Smile]](smile.gif)
Feel better!!